Interactions on record — worth a quick check against your medications. Based on 2 of 6 ingredients. Check your meds →
Dietary supplement

ABC Natural Mixed Berry Ingredients & Drug Interactions

by Core Nutritionals

ABC Natural Mixed Berry label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ABC Natural Mixed Berry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ABC Natural Mixed Berry is a dietary supplement by Core Nutritionals with 6 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against ABC Natural Mixed Berry by Core Nutritionals

Ask about any prescription or over-the-counter medication and we check it for interactions with ABC Natural Mixed Berry by Core Nutritionals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of ABC Natural Mixed Berry by Core Nutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “Branched-Chain Amino Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This powder contains 6 active ingredients. L-glutamine, L-leucine, L-isoleucine, and L-valine are amino acids—the building blocks your body uses to make and repair muscle and tissue.

Beta-alanine and citrulline malate are also amino acid compounds that support athletic and physical performance. The product also includes inactive ingredients like malic acid, natural flavor, citric acid, stevia, and silicon dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support endurance, recovery, and lean muscle building.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle breakdown, Exercise-induced muscle damage, Physical performance, Postoperative recovery, Sarcopenia — and 3 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.

The evidence for what this product actually does is mixed and depends on which ingredient you're asking about. L-glutamine shows solid evidence for sickle cell disease and some promise for helping the body recover after surgery or illness and for HIV-related muscle wasting.

Beta-alanine is possibly effective for athletic and physical performance but lacks reliable evidence for brain function, COPD, or menopausal symptoms. The effectiveness data we hold doesn't cover the other amino acids in the blend.

The evidence, ingredient by ingredient Glutamine Beta-alanine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated, though it can cause belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and gastrointestinal pain—especially at higher doses. A couple of cases of dizziness and rare reports of mood changes (mania) in people with bipolar disorder have been reported.

If you have kidney or liver disease, use it only under medical supervision. Beta-alanine commonly causes harmless skin tingling and flushing, usually starting on your scalp within 20 minutes and lasting about an hour; this is dose-dependent and mild at lower doses.

We don't hold long-term safety data for either ingredient at high doses. L-glutamine is rated likely safe in pregnancy, but beta-alanine lacks enough safety information—talk to your doctor or pharmacist if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Glutamine Beta-alanine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your anticonvulsant (seizure) medications before taking this product—L-glutamine may theoretically interfere with how they work, though this hasn't been confirmed in humans. If you take any other prescription drugs, use the medication checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is an amino acid blend aimed at athletic performance and muscle support. If you take anticonvulsant (seizure) medications, check with your pharmacist first.

People with kidney or liver disease should get medical clearance. Expect possible tingling and digestive side effects, especially at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ABC Natural Mixed Berry, straight from the product label.

Brand Core Nutritionals
Barcode (UPC) 672975315658
Net contents 2 Pound(s); 8 Ounce(s); 1.14 Kilogram(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 297831
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ABC Natural Mixed Berry by Core Nutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
22.8 Gram(s)
Maximum serving Sizes:
22.8 Gram(s)
Servings per container
50
UPC/BARCODE
672975315658
IngredientAmount% DV
L-Glutamine2.5 Gram(s)--
L-Leucine5 Gram(s)--
L-Isoleucine2.5 Gram(s)--
L-Valine2.5 Gram(s)--
Beta-Alanine2.5 Gram(s)--
Citrulline Malate2.5 Gram(s)--
Branched-Chain Amino Acids0 NP--

Other ingredients: Malic Acid, Natural flavor, Citric Acid, Stevia, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Making a great BCAA product may be complicated, and other companies may get it wrong, but Core Nutritionals makes a superior BCAA product elementary. Tested amino ratios. Proven formulas.

No unnecessary fillers.

Natural Endurance Recover Rebuild Refresh When combined with regular weight/resistance training and a healthy, balanced diet.

Manufactured in a U.S. cGMP Facility.

Formula

A: Aminos in the only clinically-verified and tested BCAA (branched chain amino acid) ratio of 2:1:1 to support endurance, recovery, and the building of lean muscle. B: Beta-Alanine has been shown to increase muscle strength and performance, increase endurance, and decrease muscular fatigue. C: Citrulline malate, at a clinical serving size, that may help to increase NO (nitric oxide) synthesis and ATP production.

Advanced BCAA supplement Mixed Berry naturally flavored

Precautions

Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov. Warning: This product is only intended for use in healthy adults 18 years of age or older.

Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.

Immediately discontinue use and consult your health care professional if you experience adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.

Warning: This product is only intended for use in healthy adults 18 years of age or older. Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Directions: Mix 2 scoops in 16-32 ounces of water and shake well. Adjust water level according to taste. Consume immediately before and during training. Additional servings can be taken throughout the day to maximize effectiveness.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

MADE IN USA

Brand IP Statement(s)

Core Nutritionals Crush It!

Storage

Protect from heat, light and moisture. Store at 10-25 degrees Celsius (50-77 degrees Fahrenheit).

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ABC Natural Mixed Berry by Core Nutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ABC Natural Mixed Berry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ABC Natural Mixed Berry by Core Nutritionals

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size22.8 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
2.5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Beta-Alanine

No known
interactions
2.5 Gram(s) per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta-Alanine monograph & interactions

Citrulline Malate

2.5 Gram(s) per serving

Branched-Chain Amino Acids

0 NP per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

Other (inactive) ingredients: Malic Acid, Natural flavor, Citric Acid, Stevia, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

ABC Natural Mixed Berry by Core Nutritionals Drug Interactions

Want to check YOUR meds against ABC Natural Mixed Berry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in ABC Natural Mixed Berry interact with 50 drugs. Click any drug to see the details.

1 of the 6 ingredients in ABC Natural Mixed Berry interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in ABC Natural Mixed Berry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ABC Natural Mixed Berry, from the product label.

Core Nutritionals

See all Core Nutritionals products
Name
Core Nutritionals, LLC
City
Statesville
State
NC
ZipCode
28625
Phone Number
(888) 978-2332
Web Address
corenutritionals.com
Pharmacist Counseling Corner

ABC Natural Mixed Berry by Core Nutritionals: Common Questions

Does ABC Natural Mixed Berry by Core Nutritionals interact with any medications?
Yes. Based on its ingredients, ABC Natural Mixed Berry has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ABC Natural Mixed Berry contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this while pregnant or breastfeeding?
L-glutamine is rated likely safe in pregnancy. Beta-alanine doesn't have enough safety information, so it's best to avoid it while pregnant or breastfeeding. Talk to your doctor or pharmacist for personalized advice on the other ingredients—we don't hold specific safety data for them in pregnancy and lactation.
What's the tingling I might feel?
That's the beta-alanine. It causes a harmless pins-and-needles sensation (paresthesia) and flushing that usually starts on your scalp within 20 minutes and lasts about an hour. It's dose-dependent—lower doses cause less tingling, and at very low doses it only happened in a quarter of people tested.
What's L-glutamine actually for?
L-glutamine is an amino acid your body uses for muscle and tissue repair. It's got solid evidence for sickle cell disease and shows promise for recovery after surgery, injury, or critical illness, and for muscle loss related to HIV. It's generally well tolerated but can cause digestive upset like bloating, constipation, nausea, and diarrhea.
Does this really improve athletic performance?
Beta-alanine, one of the active ingredients here, is possibly effective for athletic and physical performance. But we don't have good evidence that the other amino acids in this blend do, and the product hasn't been tested as a whole.
Can I take this if I have kidney or liver problems?
Not without talking to your doctor first. L-glutamine should only be used under medical supervision if you have kidney or liver disease, because how your body handles it changes when those organs aren't working normally.
What side effects might I get?
L-glutamine can cause belching, bloating, constipation, diarrhea, nausea, vomiting, gastrointestinal pain, headache, and musculoskeletal pain, especially at higher doses. Beta-alanine causes skin tingling and flushing. These are generally mild, and the tingling goes away once the dose clears your system.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ABC Natural Mixed Berry is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ABC Natural Mixed Berry label
Go deeper

The Full Monographs Behind ABC Natural Mixed Berry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph →
Sources

Sources & How We Checked

ABC Natural Mixed Berry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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