Interactions on record — worth a quick check against your medications. Based on 3 of 8 ingredients. Check your meds →
Dietary supplement

Microbiome Breakthrough Creamy Chocolate Ingredients & Drug Interactions

by BiOptimizers

Microbiome Breakthrough Creamy Chocolate label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Microbiome Breakthrough Creamy Chocolate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Microbiome Breakthrough Creamy Chocolate is a dietary supplement by BiOptimizers with 8 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,083 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Lactobacillus helveticus, Lactobacillus gasseri. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Microbiome Breakthrough Creamy Chocolate by BiOptimizers

Ask about any prescription or over-the-counter medication and we check it for interactions with Microbiome Breakthrough Creamy Chocolate by BiOptimizers — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Microbiome Breakthrough Creamy Chocolate by BiOptimizers

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 4 of its 7 active ingredients.
  • “Lactobacillus Blend” is a proprietary blend — the label gives one combined amount (65 mg) without saying how much of each component you get.

This powder has 6 active ingredients. The main ones are three Lactobacillus strains—helveticus, gasseri, and rhamnosus—which are live beneficial bacteria meant to support gut health.

You also get Bovine Collagen for structural support, IgY Max Hyperimmunized Egg Powder (antibodies from eggs), and Bovine Bone Broth for added nutrition. It's mixed into a creamy chocolate base with inactive ingredients like inulin, stevia, vanilla, and cocoa powder to keep it shelf-stable and palatable.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: improve digestive function and promote GI health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Diarrhea, Dyspepsia, Gastroparesis, Helicobacter pylori, Irritable bowel syndrome (IBS) — and 4 related terms.
  • The closest evidence on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Gasseri is rated "Insufficient Reliable Evidence To Rate" for Diarrhea, Dyspepsia, Helicobacter pylori, Irritable bowel syndrome (IBS), and more.
  • Also on file: Lactobacillus Helveticus is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea.

The evidence for what Lactobacillus helveticus and Lactobacillus gasseri actually do is insufficient right now—we don't have enough reliable data to rate them for hay fever, diarrhea, cognitive function, depression, or other conditions the research has looked at. The same goes for the other probiotic strains and the collagen or egg powder in this blend.

That doesn't mean they don't work; it means the science isn't solid enough yet to make a claim.

The evidence, ingredient by ingredient Black Psyllium Lactobacillus Helveticus Lactobacillus Gasseri

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both L. helveticus and L. gasseri are generally well tolerated in healthy people, but they're live organisms, and there isn't enough safety data on them yet. People who are seriously ill or immunocompromised need to be especially cautious, since in rare cases lactobacilli have been linked to serious infections like bacteremia or sepsis—usually when they spread from their normal location in the body.

We don't have pregnancy or breastfeeding safety data on file for any of these ingredients, so talk with your doctor or pharmacist before using this if you're pregnant or nursing.

Side effects, ingredient by ingredient Black Psyllium Lactobacillus Helveticus Lactobacillus Gasseri

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Black Psyllium, Lactobacillus Gasseri, Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,084 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotic drugs are the main concern (Moderate severity)—separate them from this product by a few hours so the antibiotics don't kill off the live probiotics. We could not check interactions for Lactobacillus rhamnosus, Bovine Collagen, IgY Max Hyperimmunized Egg Powder, or Bovine Bone Broth, so run your full medication list through the tool on this page before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-strain probiotic with collagen and egg antibodies. If you're healthy and not on antibiotics, it's worth a conversation with your pharmacist.

If you take any antibiotics, you'll need to space them out from this powder. If you're immunocompromised or seriously ill, check with your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Microbiome Breakthrough Creamy Chocolate, straight from the product label.

Brand BiOptimizers
Barcode (UPC) 0796029897393
Net contents 5.29 Ounce(s); 150 Gram(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 320979
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Microbiome Breakthrough Creamy Chocolate by BiOptimizers, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
30
UPC/BARCODE
0796029897393
IngredientAmount% DV
Calories17 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Calories from Fat0 Calorie(s)--
Total Fat1 Gram(s)1%
Dietary Fiber1 Gram(s)4%
Protein2 Gram(s)4%
Lactobacillus helveticus0 NP--
Lactobacillus gasseri0 NP--
Lactobacillus rhamnosus0 NP--
Lactobacillus Blend65 mg--
Bovine Collagen500 mg--
IgY Max Hyperimmunized Egg Powder2000 mg--
Bovine Bone Broth500 mg--

Other ingredients: Inulin, Isomaltooligosaccharides, D-Ribose, Stevia Leaf Extract, Vanilla Flavor, Cacao, Cocoa, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Microbiome Breakthrough Creamy Chocolate is a gluten-free and dairy-free blend of collagen, bone broth, IgY Max and gut-friendly bacteria, designed to improve digestive function and promote overall GI health.

Gluten free Dairy free Soy free

Formula

Microbiome Breakthrough Creamy Chocolate is a gluten-free and dairy-free blend of collagen, bone broth, IgY Max and gut-friendly bacteria, designed to improve digestive function and promote overall GI health. IgY Max has been shown in studies to improve gastrointestinal integrity by increasing beneficial flora, reducing inflammation in the gut, and reducing permeability of the gut wall. Furthermore, IgY Max has been shown to work along the entire length of the GI tract.

Prebiotics + probiotics + postbiotics

General Statements

Oh yes, and we've managed to make it taste great too!

Optimized gut health solutions

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Add one level scoop to 8 oz. of water. Take once a day on an empty stomach.

Storage

Store in a cool/dry location.

Precautions

Caution: Keep out of reach of children.

Consult with a healthcare professional if pregnant or breastfeeding.

Consult with a pediatrician before giving to children.

As with any product, discontinue immediately if adverse effects occur. Please consult a healthcare professional before beginning any new supplement, diet, training program, or if you are undergoing treatment of a medical condition.

Allergen information: Contains eggs.

To report a serious adverse event, or obtain product information, contact 1(800) 719-2467 or visit BIOptimizers.com

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

IgY Max is a registered trademark of IgY Nutrition.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Microbiome Breakthrough Creamy Chocolate by BiOptimizers label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Microbiome Breakthrough Creamy Chocolate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Microbiome Breakthrough Creamy Chocolate by BiOptimizers

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

2 Gram(s) per serving

Lactobacillus Blend

65 mg per serving

Bovine Collagen

500 mg per serving

IgY Max Hyperimmunized Egg Powder

2000 mg per serving

Bovine Bone Broth

500 mg per serving

Other (inactive) ingredients: Inulin, Isomaltooligosaccharides, D-Ribose, Stevia Leaf Extract, Vanilla Flavor, Cacao, Cocoa, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Microbiome Breakthrough Creamy Chocolate by BiOptimizers Drug Interactions

Want to check YOUR meds against Microbiome Breakthrough Creamy Chocolate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,083Drugs
205 Moderate 1,878 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Lactobacillus helveticus 182
Lactobacillus gasseri 182

Individual Drug Interactions

The ingredients in Microbiome Breakthrough Creamy Chocolate interact with 2,083 drugs. Click any drug to see the details.

3 of the 8 ingredients in Microbiome Breakthrough Creamy Chocolate interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Lactobacillus helveticus Lactobacillus gasseri

Each ingredient & the kinds of drugs it affects

For each ingredient in Microbiome Breakthrough Creamy Chocolate with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Lactobacillus helveticus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L. helveticus.
Lactobacillus helveticus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. helveticus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus helveticus full monograph & interactions

Lactobacillus gasseri1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus gasseri full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Microbiome Breakthrough Creamy Chocolate, from the product label.

BiOptimizers

See all BiOptimizers products
Name
BiOptimizers USA Inc.
Street Address
5470 Kietzke Lane, Suite 300
City
Reno
State
NV
ZipCode
89511
Web Address
Bioptimizers.com
Pharmacist Counseling Corner

Microbiome Breakthrough Creamy Chocolate by BiOptimizers: Common Questions

Does Microbiome Breakthrough Creamy Chocolate by BiOptimizers interact with any medications?
Yes. Based on its ingredients, Microbiome Breakthrough Creamy Chocolate has a known interaction with 2,083 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Microbiome Breakthrough Creamy Chocolate contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with antibiotics?
Not at the same time. Antibiotics can kill the live bacteria in this product, making it less effective. Space them out—take your antibiotic in the morning and this powder in the evening, for example. Your pharmacist can help you figure out the best timing.
Is this safe if I'm immunocompromised?
We don't have enough safety data to say yes. Since this contains live organisms, check with your doctor before using it if your immune system is weakened or you're seriously ill.
Can I take this while pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data on file for these ingredients. Talk with your doctor or pharmacist for personalized advice before using it.
What are the Lactobacillus strains for?
They're live beneficial bacteria meant to support your gut microbiome. The evidence for what they actually do—like prevent diarrhea or improve mood—isn't solid enough yet to make a reliable claim.
Will this cause side effects?
In healthy people, these probiotics are generally well tolerated. Since they're live organisms, there is a small theoretical concern about infection in some patients, though this is rare. If you feel worse after starting it, stop and call your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Microbiome Breakthrough Creamy Chocolate is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Microbiome Breakthrough Creamy Chocolate label
Go deeper

The Full Monographs Behind Microbiome Breakthrough Creamy Chocolate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Lactobacillus Helveticus

Interacts with 182 drugs

Lactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products. Early research is interesting—especial...

Read the full Lactobacillus Helveticus monograph → Herb & supplement monograph

Lactobacillus Gasseri

Interacts with 182 drugs

Lactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Early research suggests it may help with di...

Read the full Lactobacillus Gasseri monograph →
Sources

Sources & How We Checked

Microbiome Breakthrough Creamy Chocolate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
  9. Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
  10. Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
  11. Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
  12. Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed

See these in context on the Lactobacillus Gasseri monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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