Interactions on record — worth a quick check against your medications. Based on 8 of 12 ingredients. Check your meds →
Dietary supplement

kApex Ingredients & Drug Interactions

by BiOptimizers

kApex label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking kApex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

kApex is a dietary supplement by BiOptimizers with 12 active ingredients. Its ingredients are commonly taken for low stomach acid (hypochlorhydria), bloating and gas, indigestion.Based on those ingredients, 793 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dandelion, Powder, Astragalus Extract, Notoginseng extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against kApex by BiOptimizers

Ask about any prescription or over-the-counter medication and we check it for interactions with kApex by BiOptimizers — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of kApex by BiOptimizers

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 5 of its 14 active ingredients.
  • “AstraZyme” is listed as a grouped ingredient — the label gives one combined amount (50 mg) without saying how much of each component you get.
  • “Tri-Phase” is listed as a grouped ingredient — the label gives one combined amount (477 mg) without saying how much of each component you get.
  • “Lipa4 Lipase” is listed as a grouped ingredient — the label gives one combined amount (70 mg) without saying how much of each component you get.

kApex contains 14 ingredients total, of which 8 are active: betaine HCl (to support stomach acid), dandelion powder (a plant extract), ubiquinol (the active form of CoQ10, a cellular energy compound), astragalus extract (an herbal immune support), three proteases (protein-digesting enzymes), fungal lipase (a fat-digesting enzyme), and L-carnitine (an amino acid that plays a role in cellular energy). The product also contains inactive ingredients—rice extract, cellulose, and water—which serve as fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: break down fat and protein, aid digestion.
  • We looked for evidence on: Dyspepsia, Diarrhea, Constipation, Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness — and 4 related terms.
  • The closest evidence on file: Coenzyme Q10 is rated "Possibly Ineffective" for Chemotherapy-related fatigue (Natural Medicines).
  • Also on file: Coenzyme Q10 is rated "Likely Ineffective" for Athletic performance.
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence picture is mixed. Ubiquinol (CoQ10) is rated Effective for CoQ10 deficiency and Possibly Effective for fibromyalgia, migraines, heart failure, and diabetic nerve pain.

L-carnitine is Effective for L-carnitine deficiency and Possibly Effective for high cholesterol, heart failure, and angina. For the other active ingredients—betaine HCl, dandelion, astragalus, the proteases, and lipase—the evidence we hold shows Insufficient Reliable Evidence to rate their effectiveness for the conditions they're marketed for.

That doesn't mean they don't work; it means the research isn't established in our data.

The evidence, ingredient by ingredient Betaine Hydrochloride Dandelion Coenzyme Q10 Astragalus Panax Notoginseng Proteolytic Enzymes (proteases) Lipase L-carnitine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 8 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated at typical doses. Betaine HCl is not safe for people with ulcers, gastritis, or true acid reflux—it can irritate your stomach and cause heartburn.

Dandelion is usually gentle when eaten as food but can cause diarrhea, heartburn, or stomach upset at supplement doses; rare cases of allergic reactions including anaphylaxis have been reported, especially in people sensitive to ragweed and related plants. Astragalus is well tolerated short-term in healthy adults but has limited quality safety data.

The proteases may occasionally cause digestive upset or allergic reactions. CoQ10 and lipase are generally well tolerated; GI side effects are uncommon.

L-carnitine at high doses can cause stomach upset and a fishy body odor. For pregnancy: betaine HCl, dandelion, astragalus, and the proteases should be avoided—there isn't enough safety data.

CoQ10 and lipase have insufficient pregnancy data, so talk to your doctor. For breastfeeding: safety data is limited for all ingredients; check with your healthcare provider first.

Side effects, ingredient by ingredient Betaine Hydrochloride Dandelion Coenzyme Q10 Astragalus Panax Notoginseng Proteolytic Enzymes (proteases) Lipase L-carnitine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 8 matched ingredients can interact with medications — Betaine Hydrochloride, Dandelion, Panax Notoginseng, Coenzyme Q10, Astragalus, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 793 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking kApex, check your exact medications if you take: blood thinners like warfarin or acenocoumarol (Moderate), blood sugar medications (Moderate), lithium (Moderate), acid-reducing drugs like omeprazole or famotidine (Minor), or thyroid hormone replacement (Moderate). Dandelion may also reduce quinolone antibiotic levels and could interact with CYP1A2 substrates and immune suppressants.

If any of these apply, verify with your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

kApex is an enzyme and herb blend designed to support digestion. If you take blood thinners, lithium, diabetes medications, acid-reducing drugs, thyroid hormone, or certain cancer therapies, you'll want to check your specific medications with the tool below before starting.

Anyone with ulcers, gastritis, or true reflux should skip the betaine HCl. Talk to your pharmacist before adding this to your routine, especially if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 12 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about kApex, straight from the product label.

Brand BiOptimizers
Barcode (UPC) 0689176916140
Net contents 120 Veggie Cap(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334467
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for kApex by BiOptimizers, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
60
UPC/BARCODE
0689176916140
IngredientAmount% DV
Betaine HCl41.2 mg--
Dandelion, Powder1.4 mg--
Ubiquinol34 mg--
Astragalus Extract0 NP--
Protease 3.00 NP--
Protease 4.50 NP--
Protease 6.00 NP--
InnoSlim90 mg--
Lipase, Fungal0 NP--
Trace Minerals0 NP--
AstraZyme50 mg--
Notoginseng extract0 NP--
Tri-Phase477 mg--
Lipa4 Lipase70 mg--
Lipase, Fungal0 NP--
Lipase, Fungal0 NP--
L-Carnitine, Powder236 mg--

Other ingredients: Rice extract, Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

kApex is an advanced enzyme formulation designed to help break down fat and protein, aid digestion and promote ketogenesis. May support those on a high fat, ketogenic, paleo or low carb diet. May help boost energy and help maintain a healthy weight.

Optimized digestive solutions Supports keto digestion

Vegan

Gluten-free Soy-free

Formula

May support those on a high fat, ketogenic, paleo or low carb diet.

Suggested/Recommended/Usage/Directions

Directions: Take 2 capsules with each meal. (May take 2-4 capsules with each meal and 4-6 capsules upon wakening on an empty stomach.)

Storage

Store in a cool/dry location.

Precautions

Caution: Keep out of reach of children.

Do not use if ulcer or gastritis are present. As with any product, discontinue immediately if adverse effects occur. Please consult a physician before beginning any new supplement, diet, training program, or if you are undergoing treatment of a medical condition.

General Statements

To reorder or contact us, please visit: BiOptimizers.com.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

kApex by BiOptimizers label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

kApex label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in kApex by BiOptimizers

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Betaine HCl

Interacts with
36 drugs
41.2 mg per serving

Betaine hydrochloride is a supplement used to temporarily increase stomach acid in people who may have low acid levels. Evidence for its benefits is l...

Betaine HCl monograph & interactions

Dandelion, Powder

Interacts with
457 drugs
1.4 mg per serving

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for thes...

Dandelion, Powder monograph & interactions

Ubiquinol

Interacts with
198 drugs
34 mg per serving Form: Coenzyme Q-10

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Ubiquinol monograph & interactions

InnoSlim

90 mg per serving

AstraZyme

50 mg per serving

Tri-Phase

477 mg per serving Form: Endopeptidase, Exopeptidase

Lipa4 Lipase

No known
interactions
70 mg per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipa4 Lipase monograph & interactions

L-Carnitine, Powder

Interacts with
19 drugs
236 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine, Powder monograph & interactions

Other (inactive) ingredients: Rice extract, Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

kApex by BiOptimizers Drug Interactions

Want to check YOUR meds against kApex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
793Drugs
610 Moderate 183 Minor

Ingredients driving the most interactions

Dandelion, Powder 457
Astragalus Extract 208
Notoginseng extract 207
Ubiquinol 198
Betaine HCl 36

Individual Drug Interactions

The ingredients in kApex interact with 793 drugs. Click any drug to see the details.

6 of the 12 ingredients in kApex interact with drugs. Each result below shows which ingredient is responsible. Dandelion, Powder Astragalus Extract Notoginseng extract Ubiquinol Betaine HCl L-Carnitine, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in kApex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dandelion, Powder7 drug types · 457 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking dandelion root along with anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro research suggests that dandelion root inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, dandelion might increase the risk for hypoglycemia when used with antidiabetes drugs.
Laboratory research suggests that dandelion extract may have moderate alpha-glucosidase inhibitor activity and might also increase insulin secretion. Also, in a case report, a 58-year-old woman with type 2 diabetes who was being treated with insulin developed hypoglycemia 2 weeks after beginning to eat salads containing dandelion.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, dandelion might increase levels of drugs metabolized by CYP1A2.
Laboratory research suggests that dandelion might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, until more is known, watch for an increase in the levels of drugs metabolized by CYP1A2 in patients taking dandelion.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, dandelion might increase the clearance of drugs that are UDP-glucuronosyltransferase substrates.
There is some preliminary evidence that dandelion might induce UDP-glucuronosyltransferase, a phase II enzyme.

Likelihood Possible Evidence D
Lithium

Theoretically, through diuretic effects, dandelion might reduce excretion and increase levels of lithium.
Animal research suggests that dandelion has diuretic properties. As diuretics can increase serum lithium levels, the dose of lithium might need to be decreased when taken with dandelion.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically, dandelion might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Dandelion contains significant amounts of potassium.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, dandelion might lower fluoroquinolone levels.
Animal research shows that dandelion reduces absorption of ciprofloxacin and can lower levels by 73%. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Dandelion, Powder full monograph & interactions

Astragalus Extract4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus Extract full monograph & interactions

Notoginseng extract4 drug types · 207 drugs

Aspirin

Theoretically, taking Panax notoginseng concomitantly with aspirin may increase the risk of adverse effects from both products.
Animal research shows that taking Panax notoginseng extract with aspirin increases blood levels of salicylic acid by approximately 50% and blood levels of Panax notoginseng by 75% to 196%. This effect may be due to increased absorption of both products.

Likelihood Possible Evidence D
Caffeine

Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction is attributed to the ability of Panax notoginseng to increase the activity of cytochrome P450 1A2 (CYP1A2) enzymes.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction was attributed to the ability of Panax notoginseng to increase the activity of CYP1A2.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking Panax notoginseng concomitantly with warfarin may increase the risk of bleeding.
Animal research shows that taking Panax notoginseng concomitantly with warfarin increases plasma warfarin levels, prothrombin time, and international normalized ratio when compared with control. In vitro research also suggests that Panax notoginseng may downregulate expression of cytochrome P450 3A4 enzymes, which may affect warfarin metabolism.

Likelihood Possible Evidence D
Notoginseng extract full monograph & interactions

Ubiquinol3 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Ubiquinol full monograph & interactions

Betaine HCl3 drug types · 36 drugs

Antacids

Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
In human research, betaine hydrochloride increases stomach acidity. Antacids are taken to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with antacids might decrease the effects of the antacids.

Likelihood Possible Evidence D
H2-Blockers

Betaine hydrochloride increases stomach acidity and could decrease the effects of H2-blockers.
In human research, betaine hydrochloride increases stomach acidity. H2-blockers are used to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with H2-blockers might decrease the effects of H2-blockers.

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Betaine hydrochloride increases stomach acidity and could decrease the effects of PPIs.
In human research, betaine hydrochloride increases stomach acidity. PPIs are used to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with PPIs might decrease the effects of PPIs

Likelihood Possible Evidence D
Betaine HCl full monograph & interactions

L-Carnitine, Powder3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for kApex, from the product label.

BiOptimizers

See all BiOptimizers products
Name
BiOptimizers USA Inc.
Street Address
5470 Kietzke Lane, Suite 300
City
Reno
State
NV
ZipCode
89511
Web Address
Bioptimizers.com
Pharmacist Counseling Corner

kApex by BiOptimizers: Common Questions

Does kApex by BiOptimizers interact with any medications?
Yes. Based on its ingredients, kApex has a known interaction with 793 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
kApex contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my digestion?
The product contains digestive enzymes and betaine HCl meant to support stomach acid and break down food. However, we don't have strong evidence in our data that these ingredients work for digestive complaints. A pharmacist can help you figure out if this matches your specific situation.
Can I take this if I have acid reflux?
No. Betaine HCl increases stomach acidity and isn't safe for people with true acid reflux—it can make heartburn worse and may irritate your stomach.
Is this safe during pregnancy?
There isn't enough safety data for most of these ingredients in pregnancy, and several should be avoided. Talk to your doctor before taking it.
What's in the 'blend' ingredients like AstraZyme and Tri-Phase?
Those are containers that hold other active ingredients already listed separately on the label—astragalus and enzymes. The product facts don't break down their exact doses, so we can't tell you more detail.
Does this have fillers?
Yes. The inactive ingredients are rice extract, cellulose, and water—these are binders and capsule materials.
What does CoQ10 (ubiquinol) do?
CoQ10 is a compound your cells use for energy. It's rated Effective for CoQ10 deficiency and Possibly Effective for migraines, heart failure, fibromyalgia, and nerve pain in diabetes. It may also slightly lower blood pressure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

kApex label
Go deeper

The Full Monographs Behind kApex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Betaine Hydrochloride

Interacts with 36 drugs

Betaine hydrochloride is a supplement used to temporarily increase stomach acid in people who may have low acid levels. Evidence for its benefits is limited and mostly based on tradition rat...

Read the full Betaine Hydrochloride monograph → Herb & supplement monograph

Dandelion

Interacts with 457 drugs

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for these uses is very limited, so its benefits...

Read the full Dandelion monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph → Herb & supplement monograph

Panax Notoginseng

Interacts with 207 drugs

Panax notoginseng (sanqi or tienchi ginseng) is a traditional Chinese herb most often used to help with bleeding, bruising, and circulation. Human evidence for these uses is limited and most...

Read the full Panax Notoginseng monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph →
Sources

Sources & How We Checked

kApex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 142 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Betaine Hydrochloride 2 references
  1. Yago MR, Frymoyer A, Benet LZ, Smelick GS, Frassetto LA, Ding X, Dean B, Salphati L, Budha N, Jin JY, Dresser MJ, Ware JA. The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria. AAPS J. 2014 PubMed
  2. Yago MR, Frymoyer AR, Smelick GS, Frassetto LA, Budha NR, Dresser MJ, Ware JA, Benet LZ. Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria. Mol Pharm. 2013 Nov 4;10(11):4032-7. PubMed

See these in context on the Betaine Hydrochloride monograph →

Dandelion 27 references
  1. Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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