MycoShield Spray Winter Mist Ingredients & Drug Interactions
What is this page for?
First and foremost: checking MycoShield Spray Winter Mist against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
MycoShield Spray Winter Mist is a dietary supplement by Host Defense Mushrooms with 5 active ingredients. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 501 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mycelium Extract, Fresh, Chaga Mycelium Extract, Fresh, Birch Polypore Mycelium Extract, Fresh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against MycoShield Spray Winter Mist by Host Defense Mushrooms
Ask about any prescription or over-the-counter medication and we check it for interactions with MycoShield Spray Winter Mist by Host Defense Mushrooms — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of MycoShield Spray Winter Mist by Host Defense Mushrooms
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
MycoShield Spray contains five active ingredients: a proprietary extract blend and four fresh mycelium extracts — agarikon, reishi, chaga, and turkey tail mushrooms. The inactive ingredients are water, alcohol, and sweet birch oil.
Does it work?
Couldn't assess
The evidence base for these ingredients is limited. For reishi, the data we hold shows it is possibly ineffective for high cholesterol (hyperlipidemia), and there is insufficient evidence to rate it for altitude sickness, Alzheimer disease, or athletic performance.
Chaga and birch similarly lack reliable evidence for the conditions we have on file — including heart disease, diabetes, COVID-19, joint pain, hair loss, and dandruff. Agarikon and turkey tail have no effectiveness ratings in our data.
How safe is it?
Well-documented data
Reishi and chaga are generally well tolerated when taken by mouth short-term, though long-term safety hasn't been well studied. Reishi's most common side effects include dizziness, dry mouth, itching, nausea, rash, and stomach upset; rare effects are insomnia and headache.
Respiratory allergy to reishi spores can also occur, with sore throat and runny nose reported. Chaga has caused kidney failure and acute kidney injury in cases of excessive use due to high oxalate content.
Birch is generally well tolerated in food-like amounts but can trigger allergic reactions in people sensitive to birch pollen or birch bark. During pregnancy, the safety data for reishi, chaga, and birch all advise against use; the same holds for breastfeeding.
Data on agarikon and turkey tail safety in pregnancy and breastfeeding is not on file.
Meds to double-check
Moderate interaction found
Before taking MycoShield Spray, double-check if you're on any blood thinners or antiplatelet drugs (moderate severity), blood pressure medications, diabetes drugs, or immune-suppressing drugs (all moderate). Also ask about diuretics or water pills (minor severity).
We could not check agarikon or turkey tail for interactions.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This spray combines several mushroom extracts with a modest evidence base and documented interactions with blood thinners, blood pressure drugs, diabetes medications, and immune-suppressing drugs. If you take any of those, talk with your doctor or pharmacist before starting this product.
Even if you don't, check your full medication list with the tool on this page — altogether, these interactions span 501 individual medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about MycoShield Spray Winter Mist, straight from the product label.
| Brand | Host Defense Mushrooms |
|---|---|
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2024 |
| DSLD ID | 312598 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for MycoShield Spray Winter Mist by Host Defense Mushrooms, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 0.42 mL | -- |
| Agarikon Mycelium Extract, Fresh | 0 NP | -- |
| Reishi Mycelium Extract, Fresh | 0 NP | -- |
| Chaga Mycelium Extract, Fresh | 0 NP | -- |
| Birch Polypore Mycelium Extract, Fresh | 0 NP | -- |
| Turkey Tail Mycelium Extract, Fresh | 0 NP | -- |
Other ingredients: Water, Alcohol, sweet Birch Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Apply three pump sprays into mouth, then swallow, twice per day. Shake well before using. Can be taken with food, on an empty stomach, or as recommended by your healthcare professional.
Precautions
Do not inhale while spraying. Avoid contact with eyes.
Caution: If you have a medical condition, are taking medications, or are pregnant or breastfeeding, consult your healthcare professional before using this product.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
USDA Organic
Certified organic Washington State Department of Agriculture Organic Program
Formulation
Non GMO Gluten free
On-The-Go Immune support
Certified Organic by the WSDA
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
MycoShield Spray Winter Mist by Host Defense Mushrooms label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in MycoShield Spray Winter Mist by Host Defense Mushrooms
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.42 mL Dosage formLiquid Servings per container71 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Agarikon Mycelium Extract, Fresh
- › Reishi Mycelium Extract, Fresh
- › Chaga Mycelium Extract, Fresh
- › Birch Polypore Mycelium Extract, Fresh
- › Turkey Tail Mycelium Extract, Fresh
Other (inactive) ingredients: Water, Alcohol, Sweet Birch Oil. These complete the product’s ingredient list but are not active constituents.
MycoShield Spray Winter Mist by Host Defense Mushrooms Drug Interactions
HelloPharmacist Interaction Report
MycoShield Spray Winter Mist by Host Defense Mushrooms contains several mushroom extracts, and through its reishi, chaga, and birch content, this product does interact with medications.
The most serious concern is a moderate-severity interaction between reishi and blood thinners (anticoagulant and antiplatelet drugs): at higher doses, reishi may increase bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Reishi also interacts moderately with blood pressure medications (antihypertensive drugs) — it can lower blood pressure on its own, so combining it with a blood pressure drug might drop your pressure too much. Additionally, both reishi and chaga interact with diabetes medications: theoretically, both could add to the blood-sugar-lowering effect of your drug, raising the risk of low blood sugar (hypoglycemia).
Chaga carries a moderate interaction with immune-suppressing drugs, which it might interfere with, and birch carries a minor interaction with diuretics (water pills).
We could not check agarikon or turkey tail — interaction data isn't available for those ingredients. Run your exact medications through the tool below before starting this spray.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against MycoShield Spray Winter Mist?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in MycoShield Spray Winter Mist interact with 501 drugs. Click any drug to see the details.
3 of the 5 ingredients in MycoShield Spray Winter Mist interact with drugs. Each result below shows which ingredient is responsible. Reishi Mycelium Extract, Fresh Chaga Mycelium Extract, Fresh Birch Polypore Mycelium Extract, Fresh
Aspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Caffeine, Orphenadrine interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Carisoprodol interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Carisoprodol, Codeine Phosphate interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Citric Acid, Sodium Bicarbonate interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Codeine Phosphate interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Codeine Phosphate, Methocarbamol interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Codeine Phosphate, Phenobarbital interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Diphenhydramine, Phenylpropanolamine interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Dipyridamole interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Ethoheptazine, Meprobamate interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Hydrocodone interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Meprobamate interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Methocarbamol interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Omeprazole interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Oxycodone interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aspirin, Pentazocine interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aspirin, Pentazocine interactionAtenololAtenix, Tenormin
How Atenolol interacts with MycoShield Spray Winter Mist — through 1 ingredient. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Atenolol, Chlortalidone interactionBirch Polypore Mycelium Extract, FreshDiuretic Drugs Minor
Interaction Summary
Theoretically, birch might interfere with diuretic therapy.
Read the full Birch Polypore Mycelium Extract, Fresh + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Atenolol, Chlorthalidone interactionBirch Polypore Mycelium Extract, FreshDiuretic Drugs Minor
Interaction Summary
Theoretically, birch might interfere with diuretic therapy.
Read the full Birch Polypore Mycelium Extract, Fresh + Atenolol, Chlorthalidone interactionAtezolizumabTecentriq
How Atezolizumab interacts with MycoShield Spray Winter Mist — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Atezolizumab interactionAzamuneImmunoprin
How Azamune interacts with MycoShield Spray Winter Mist — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with MycoShield Spray Winter Mist — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Azathioprine interactionAzilsartanEdarbi
How Azilsartan interacts with MycoShield Spray Winter Mist — through 1 ingredient. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with MycoShield Spray Winter Mist — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Azilsartan, Chlorthalidone interactionBirch Polypore Mycelium Extract, FreshDiuretic Drugs Minor
Interaction Summary
Theoretically, birch might interfere with diuretic therapy.
Read the full Birch Polypore Mycelium Extract, Fresh + Azilsartan, Chlorthalidone interactionBasiliximabSimulect
How Basiliximab interacts with MycoShield Spray Winter Mist — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Basiliximab interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with MycoShield Spray Winter Mist — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Beclometasone Dipropionate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in MycoShield Spray Winter Mist with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Reishi Mycelium Extract, Fresh
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
Chaga Mycelium Extract, Fresh
Anticoagulant/Antiplatelet Drugs
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.
Antidiabetes Drugs
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.
Immunosuppressants
Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.
Birch Polypore Mycelium Extract, Fresh
Diuretic Drugs
Theoretically, birch might interfere with diuretic therapy.
Brand information
Manufacturer and brand details for MycoShield Spray Winter Mist, from the product label.
Host Defense Mushrooms
See all Host Defense Mushrooms products- Name
- Fungi Perfecti, LLC
- Street Address
- PO Box 7634
- City
- Olympia
- State
- WA
- ZipCode
- 98507
- Phone Number
- 877-504-6926
- Web Address
- Hostdefense.com
MycoShield Spray Winter Mist by Host Defense Mushrooms: Common Questions
Does MycoShield Spray Winter Mist by Host Defense Mushrooms interact with any medications?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind MycoShield Spray Winter Mist’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Reishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph → Herb & supplement monographChaga
Interacts with 327 drugsChaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...
Read the full Chaga monograph → Herb & supplement monographBirch
Interacts with 75 drugsBirch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid human evidence is limited, and birch is...
Read the full Birch monograph →Sources & How We Checked
MycoShield Spray Winter Mist's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
- Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
- Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
- Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
- Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
- Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
- Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
- Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
- Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
- Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
- Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
- Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
- Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
- Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
- Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
- Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.
Chaga 9 references
- Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
- Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
- Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
- Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
- Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
- Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
- Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
- Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
- Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed
Birch 4 references
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
- Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
- Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC