Neurolink Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Neurolink against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Neurolink is a dietary supplement by Designs for Health with 7 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 674 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GABA, 5-HTP, Vitamin B-6. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Neurolink by Designs for Health
Ask about any prescription or over-the-counter medication and we check it for interactions with Neurolink by Designs for Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Neurolink by Designs for Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Neurolink contains 7 active ingredients: L-Glutamine, Taurine, L-Tyrosine, Inositol, 5-HTP, Vitamin B-6, and GABA. These amino acids and neurotransmitter precursors are intended to support brain function and nervous system health.
The capsules also contain microcrystalline cellulose, vegetable stearate, and rice flour as inactive ingredients.
Does it work?
Strong evidence
The evidence for these ingredients is mixed. L-Glutamine is effective for sickle cell disease and possibly effective for recovery after surgery and certain wasting conditions.
L-Tyrosine is effective for a rare amino acid disorder (phenylketonuria) and possibly effective for memory and focus. Inositol is possibly effective for polycystic ovary syndrome and metabolic syndrome.
Vitamin B-6 is effective for certain types of anemia and vitamin B-6 deficiency itself. 5-HTP is possibly effective for depression.
Taurine and GABA lack sufficient evidence in our data to rate their effectiveness for general brain health or the purposes this product implies.
How safe is it?
Well-documented data
Most of these ingredients are generally well tolerated at standard doses, though they come with caveats. L-Glutamine, Taurine, L-Tyrosine, and Inositol are mostly mild and digestive—think bloating, nausea, or diarrhea.
5-HTP carries more caution: it's avoided in pregnancy and breastfeeding due to insufficient safety data, and it affects serotonin levels, so it requires careful use and professional guidance. Vitamin B-6 is safe at normal supplement doses, but long-term high doses can damage nerves (sensory neuropathy).
GABA's long-term safety isn't well studied, and it's best avoided in pregnancy and while breastfeeding. People with kidney or liver disease should use L-Glutamine only under medical supervision.
Meds to double-check
Moderate interaction found
Before taking Neurolink, double-check these medication types with your doctor or pharmacist: anticonvulsant (seizure) drugs, because L-Glutamine may reduce their effect; blood pressure medications, since Taurine, Vitamin B-6, and GABA may lower pressure further; lithium, because Taurine may raise its levels; Parkinson's medications (levodopa), because L-Tyrosine and Vitamin B-6 may interfere; thyroid hormone, because L-Tyrosine may add to its effects; diabetes medications, because Inositol may increase the blood-sugar-lowering effect; and antidepressants or other serotonin-boosting drugs, because 5-HTP may cause serotonin-related side effects. Also mention amiodarone and older seizure drugs (phenobarbital, phenytoin) if you take them.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Neurolink is a multi-ingredient formula aimed at brain support, but it contains several ingredients that interact with common medications—especially blood pressure drugs, seizure medications, antidepressants, and diabetes drugs. If you take any prescription or over-the-counter medication regularly, check your exact medications with the tool on this page, or talk with your doctor or pharmacist before you start.
The evidence that these ingredients work together for general brain health is thin; most ratings are for specific conditions (anemia, PCOS, surgery recovery), not everyday cognitive support.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 7 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Neurolink, straight from the product label.
| Brand | Designs for Health |
|---|---|
| Barcode (UPC) | 879452000476 |
| Net contents | 180 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2013 |
| DSLD ID | 22478 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Neurolink by Designs for Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Glutamine | 600 mg | -- |
| Taurine | 600 mg | -- |
| L-Tyrosine | 1200 mg | -- |
| Inositol | 600 mg | -- |
| 5-HTP | 150 mg | -- |
| Vitamin B-6 | 30 mg | 1500% |
| GABA | 750 mg | -- |
Other ingredients: Microcrystalline Cellulose, Vegetable Stearate, Rice Flour
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Notice: Color, size or shape may appear different between lots.
For Professional Use Only
Manufactured in an NSF GMP Registered Facility
Formulation
Does not contain gluten.
General
NEU180-1
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Guaranteed GMP CERTIFIED Products
Suggested/Recommended/Usage/Directions
Recommended Use: As a dietary supplement, take a total of six capsules per day, in divided doses on an empty stomach, or as directed by your health care practitioner.
Storage
STORE IN A COOL, DRY PLACE.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Neurolink by Designs for Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Neurolink by Designs for Health
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Glutamine
Interacts with50 drugs
Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...
L-Glutamine monograph & interactionsTaurine
Interacts with173 drugs
Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...
Taurine monograph & interactionsL-Tyrosine
Interacts with21 drugs
L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performan...
L-Tyrosine monograph & interactionsInositol
Interacts with86 drugs
Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...
Inositol monograph & interactions5-HTP
Interacts with398 drugs
5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches. Some early rese...
5-HTP monograph & interactionsVitamin B-6
Interacts with210 drugs
Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...
Vitamin B-6 monograph & interactionsGABA
Interacts with419 drugs
GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...
GABA monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Vegetable Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.
Neurolink by Designs for Health Drug Interactions
HelloPharmacist Interaction Report
Neurolink by Designs for Health contains seven active ingredients, and several of them interact with medications.
The most serious interaction we've documented is between L-Glutamine and anticonvulsant drugs (Moderate severity)—glutamine is converted to an excitatory neurotransmitter that may work against seizure medications, though this hasn't been reported in humans yet.
Read the full breakdown — every affected drug type, severity by severity
Taurine may reduce blood pressure further if you're already taking blood pressure medications, and it might also increase lithium levels if you're on that. L-Tyrosine can compete with levodopa (used for Parkinson's disease) for absorption, and it may add to the effects of thyroid hormone medications.
Inositol may increase the blood-sugar-lowering effect of diabetes medications, raising the risk of low blood sugar. Vitamin B-6 at high doses may decrease the effectiveness of older seizure drugs (phenobarbital and phenytoin), increase sun sensitivity if you're on amiodarone, and add to blood pressure reduction with antihypertensive drugs.
5-HTP interacts with a broad range of medications: it can add to the sedating effects of CNS depressants, combine dangerously with serotonin-boosting drugs (like antidepressants) to raise the risk of serotonin syndrome, and it may cause unwanted effects when used with carbidopa. GABA may lower blood pressure further with antihypertensive drugs and could add drowsiness to sedating medications, though the real-world relevance of that second concern is unclear.
Altogether, these interactions span 674 individual medications. Use the interaction checker below with your exact prescriptions before starting this product, and talk with your doctor or pharmacist about whether it's right for you.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Neurolink?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Neurolink interact with 674 drugs. Click any drug to see the details.
7 of the 7 ingredients in Neurolink interact with drugs. Each result below shows which ingredient is responsible. GABA 5-HTP Vitamin B-6 Taurine Inositol L-Glutamine L-Tyrosine
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Neurolink — through 3 ingredients. Tap an ingredient for the detail:
Vitamin B-6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B-6 + Acebutolol interactionGabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Acebutolol interactionTaurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Taurine + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acepromazine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acepromazine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Butalbital, Caffeine, Codeine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Butalbital, Codeine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Butalbital, Codeine Phosphate interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Codeine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Codeine, Salicylamide interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Dihydrocodeine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpSerotonergic Drugs, Cns Depressants Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpSerotonergic Drugs, Cns Depressants Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Chlorzoxazone, Codeine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Codeine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Codeine, Doxylamine interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Neurolink — through 2 ingredients. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Codeine, Methocarbamol interactionGabaCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Neurolink — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Neurolink with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
GABA
Antihypertensive Drugs
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.
Cns Depressants
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.
5-HTP
Carbidopa (Lodosyn)
Combining 5-HTP and carbidopa can increase the risk of serotonergic side effects.
Carbidopa is sometimes used with 5-HTP to minimize peripheral 5-HTP metabolism and boost the amount that reaches the brain. However, this combination might also increase the risk of some side effects including hypomania, restlessness, rapid speech, anxiety, insomnia, and aggressiveness. Combining carbidopa and 5-HTP might also increase the risk of scleroderma-like skin changes due to elevated serotonin levels.
Cns Depressants
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
In clinical trials, 5-HTP has been associated with drowsiness and somnolence.
Serotonergic Drugs
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
5-HTP can increase serotonin levels and cause serotonergic effects. Theoretically, combining serotonergic drugs with 5-HTP might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders. However, serotonin syndrome with 5-HTP has not yet been reported in humans. Monitor patients for signs of serotonin syndrome and other serotonergic side effects if using 5-HTP with serotonergic drugs.
Vitamin B-6
Amiodarone (Cordarone)
Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.
Antihypertensive Drugs
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.
Phenobarbital (Luminal)
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.
Phenytoin (Dilantin)
High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.
Levodopa
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.
Taurine
Antihypertensive Drugs
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.
Lithium
Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.
Inositol
Antidiabetes Drugs
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.
L-Glutamine
Anticonvulsants
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.
L-Tyrosine
Levodopa
Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.
Thyroid Hormone
Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.
Brand information
Manufacturer and brand details for Neurolink, from the product label.
Designs for Health
See all Designs for Health products- Name
- Designs for Health, Inc.
- Street Address
- 980 South Street
- City
- Suffield
- State
- CT
- ZipCode
- 06078
- Web Address
- www.designsforhealth.com
Neurolink by Designs for Health: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Neurolink’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Glutamine
Interacts with 50 drugsGlutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...
Read the full Glutamine monograph → Herb & supplement monographTaurine
Interacts with 173 drugsTaurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...
Read the full Taurine monograph → Herb & supplement monographTyrosine
Interacts with 21 drugsL-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss,...
Read the full Tyrosine monograph → Herb & supplement monographInositol
Interacts with 86 drugsInositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...
Read the full Inositol monograph → Herb & supplement monograph5-htp
Interacts with 398 drugs5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches. Some early research is promising, but the overall evide...
Read the full 5-htp monograph → Herb & supplement monographVitamin B6
Interacts with 210 drugsVitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...
Read the full Vitamin B6 monograph → Herb & supplement monographGamma-aminobutyric Acid (gaba)
Interacts with 419 drugsGABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...
Read the full Gamma-aminobutyric Acid (gaba) monograph →Sources & How We Checked
Neurolink's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 126 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glutamine 11 references
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Taurine 21 references
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- Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
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- Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
- Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
- Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
- Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
- Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
- Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
- Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
- Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
- Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
- Higgins JP, Liras GN, Liras IN, et al. Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults. Cardiology. 2021;146(2):258-262. PubMed
- Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed
Tyrosine 4 references
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- DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
- Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
- van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed
Inositol 14 references
- Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
- Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
- Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
- Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
- Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
- Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
- Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
- Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
- Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
- Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
- Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
- Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
- Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
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5-htp 32 references
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Gamma-aminobutyric Acid (gaba) 12 references
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See these in context on the Gamma-aminobutyric Acid (gaba) monograph →
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