Interactions on record — worth a quick check against your medications. Based on 5 of 7 ingredients. Check your meds →
Dietary supplement

Night-Time Weight Loss Formula Ingredients & Drug Interactions

by Elevate Recovery Supplements

Night-Time Weight Loss Formula label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Night-Time Weight Loss Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Night-Time Weight Loss Formula is a dietary supplement by Elevate Recovery Supplements with 7 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 454 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Arginine, L-Glutamine, L-Lysine Hydrochloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Night-Time Weight Loss Formula by Elevate Recovery Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Night-Time Weight Loss Formula by Elevate Recovery Supplements — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Night-Time Weight Loss Formula by Elevate Recovery Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 7 of its 7 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This formula contains 7 ingredients, including five amino acids: L-glutamine, L-lysine hydrochloride, L-glycine, L-ornithine hydrochloride, and L-arginine. It also includes ornithine alpha-ketoglutarate (another form of ornithine) and colostrum powder.

The amino acids are the active components — they're building blocks your body uses for muscle, immune function, and tissue repair. The formula rounds out with inactive ingredients: gelatin, rice flour, vegetable magnesium stearate, and silicon dioxide, which help form and stabilize the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: supports weight loss while you sleep.
  • We looked for evidence on: Obesity, Metabolic syndrome, Diabetes, Prediabetes, Weight management, Metabolic health — and 1 related terms.
  • The closest evidence on file: Lysine is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Obesity, Prediabetes.
  • Also on file: Glycine is rated "Insufficient Reliable Evidence To Rate" for Obesity, Metabolic syndrome.

The evidence for each ingredient in this formula is mixed and limited. L-glutamine is effective for sickle cell disease but only possibly effective for HIV/AIDS-related wasting and recovery after surgery or critical illness.

L-lysine is possibly effective for cold sores (herpes labialis) but we don't have enough evidence to rate it for growth support, pressure ulcers, or diabetic foot ulcers. L-glycine is possibly effective for schizophrenia but lacks reliable evidence for other listed uses like ADHD or benign prostatic hyperplasia.

Both ornithine forms are possibly effective for athletic performance but insufficient evidence exists for dry skin, insomnia, or periodontitis. L-arginine has no established effectiveness ratings in our data.

Overall, the formula's usefulness for weight loss specifically is not established in the data we hold.

The evidence, ingredient by ingredient Glutamine Lysine Glycine Ornithine L-arginine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these amino acids are generally well tolerated at typical doses. L-glutamine commonly causes belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and gastrointestinal pain; rare cases of dizziness and headache have occurred.

L-lysine can cause abdominal pain, diarrhea, and indigestion; one case of kidney damage has been reported with long-term use. L-glycine rarely causes mild sedation, irritability, insomnia, fatigue, headache, soft stools, nausea, vomiting, or dry mouth.

L-arginine commonly causes abdominal pain, bloating, nausea, diarrhea, headache, insomnia, and flushing; when inhaled it can inflame airways. For pregnancy, L-glutamine is likely safe and L-arginine is possibly safe, but L-lysine, L-glycine, L-ornithine hydrochloride, and ornithine alpha-ketoglutarate lack enough safety data — pregnancy use of these should be discussed with your doctor.

For breastfeeding, safety data are insufficient for all ingredients; talk to your pharmacist or doctor before using this while nursing.

Side effects, ingredient by ingredient Glutamine Lysine Glycine Ornithine L-arginine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Lysine, L-arginine, Glutamine, Glycine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications.
  • For scale: 454 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this if you take blood pressure medications (ACE inhibitors, ARBs, or other antihypertensives), potassium-sparing diuretics, blood thinners or antiplatelet drugs, diabetes medications, antiseizure drugs, or clozapine (Clozaril). L-arginine interactions with blood pressure and potassium levels are the most serious.

No interactions are documented for colostrum powder in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood pressure medication, potassium-sparing diuretics, blood thinners, diabetes drugs, or antiseizure medication, talk to your pharmacist before starting this formula — several ingredients interact with these drug classes. People with kidney or liver disease should use it only under medical supervision.

This product may help with specific conditions like cold sores or athletic performance, but evidence for weight loss isn't established here. Your pharmacist can help you check whether it's safe alongside your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Night-Time Weight Loss Formula, straight from the product label.

Brand Elevate Recovery Supplements
Barcode (UPC) 653552985747
Net contents 60 Capsule(s)
Market status Off market
Date entered into DSLD Jan 22, 2022
DSLD ID 257903
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Night-Time Weight Loss Formula by Elevate Recovery Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
653552985747
IngredientAmount% DV
L-Glutamine150 mg--
L-Lysine Hydrochloride50 mg--
L-Glycine50 mg--
L-Ornithine Hydrochloride150 mg--
L-Arginine200 mg--
Colostrum Powder100 mg--
Ornithine Alpha- Ketoglutarate50 mg--

Other ingredients: Gelatin, Rice Flour, Vegetable Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 1 capsules with 8 ounces of water on an empty stomach at bedtime or as directed by a healthcare professional. For best results, avoid eating 2 hours before and after use.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Allergen warning: contains milk (colostrum)

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Weight loss formula Supports weight loss while you sleep

General Statements

2 month supply

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Night-Time Weight Loss Formula by Elevate Recovery Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Night-Time Weight Loss Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Night-Time Weight Loss Formula by Elevate Recovery Supplements

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
150 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

L-Lysine Hydrochloride

Interacts with
1 drug
50 mg per serving

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine Hydrochloride monograph & interactions

L-Glycine

Interacts with
1 drug
50 mg per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

L-Glycine monograph & interactions

L-Ornithine Hydrochloride

No known
interactions
150 mg per serving

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement fo...

L-Ornithine Hydrochloride monograph & interactions

L-Arginine

Interacts with
403 drugs
200 mg per serving Form: L-Arginine

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for bl...

L-Arginine monograph & interactions

Colostrum Powder

100 mg per serving Form: Bovine

Ornithine Alpha- Ketoglutarate

No known
interactions
50 mg per serving

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement fo...

Ornithine Alpha- Ketoglutarate monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Night-Time Weight Loss Formula by Elevate Recovery Supplements Drug Interactions

Want to check YOUR meds against Night-Time Weight Loss Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
454Drugs
445 Moderate 9 Minor

Ingredients driving the most interactions

L-Arginine 403
L-Glutamine 50
L-Lysine Hydrochloride 1
L-Glycine 1

Individual Drug Interactions

The ingredients in Night-Time Weight Loss Formula interact with 454 drugs. Click any drug to see the details.

4 of the 7 ingredients in Night-Time Weight Loss Formula interact with drugs. Each result below shows which ingredient is responsible. L-Arginine L-Glutamine L-Lysine Hydrochloride L-Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in Night-Time Weight Loss Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Arginine9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions

L-Lysine Hydrochloride1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
L-Lysine Hydrochloride full monograph & interactions

L-Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
L-Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Night-Time Weight Loss Formula, from the product label.

Elevate Recovery Supplements

See all Elevate Recovery Supplements products
Name
Elevate Recovery Supplements, LLC
Street Address
8700 Stonebrook Parkway #2112
City
Frisco
State
TX
ZipCode
75034
Web Address
www.ElevateRecovery.com
Pharmacist Counseling Corner

Night-Time Weight Loss Formula by Elevate Recovery Supplements: Common Questions

Does Night-Time Weight Loss Formula by Elevate Recovery Supplements interact with any medications?
Yes. Based on its ingredients, Night-Time Weight Loss Formula has a known interaction with 454 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Night-Time Weight Loss Formula contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while pregnant?
L-glutamine is likely safe in pregnancy, and L-arginine is possibly safe, but L-lysine, L-glycine, and the ornithine forms don't have enough safety data to know either way. Talk with your doctor or pharmacist before starting this formula while pregnant — they can give you personalized advice based on your health.
Can I take this while breastfeeding?
There isn't enough reliable information for any of the active ingredients in this formula while breastfeeding. It's best to talk with your doctor or pharmacist first to decide whether it's right for you.
Will this help me lose weight?
We don't have effectiveness data showing this formula works for weight loss. The individual amino acids are possibly effective for other purposes — like L-lysine for cold sores or L-ornithine for athletic performance — but weight loss isn't established in the data we hold.
What's the most common side effect?
L-glutamine and L-arginine both commonly cause stomach upset — bloating, nausea, diarrhea, abdominal pain, and constipation. L-lysine can cause similar digestive issues. These are usually mild at typical doses.
Does this formula have any fillers?
Yes, it contains four inactive ingredients: gelatin, rice flour, vegetable magnesium stearate, and silicon dioxide. These help form and stabilize the capsule.
What is L-arginine and what does it do?
L-arginine is an amino acid your body uses for many functions, including blood vessel health and immune support. It increases nitric oxide, which relaxes blood vessels — that's why it can lower blood pressure and is a major source of interactions in this formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Night-Time Weight Loss Formula label
Go deeper

The Full Monographs Behind Night-Time Weight Loss Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Lysine

Interacts with 1 drug

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...

Read the full Lysine monograph → Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph → Herb & supplement monograph

Ornithine

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement for fatigue, exercise recovery, and sleep,...

Read the full Ornithine monograph → Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph →
Sources

Sources & How We Checked

Night-Time Weight Loss Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 90 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Lysine 7 references
  1. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
  2. McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
  3. DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
  4. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  5. Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
  6. Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
  7. Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.

See these in context on the Lysine monograph →

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Ornithine 1 reference
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the Ornithine monograph →

L-arginine 66 references
  1. Sapienza MA, Kharitonov SA, Horvath I, et al. Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Thorax 1998;53:172-5.
  2. Clarkson P, Adams MR, Powe AJ, et al. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults. J Clin Invest 1996;97:1989-94. PubMed
  3. Tenenbaum A, Fisman EZ, Motro M. L-arginine: Rediscovery in progress. Cardiology 1998;90:153-9.
  4. Brittenden J, Park KGM, Heys SD, et al. L-Arginine stimulates host defenses in patients with breast cancer. Surgery 1994;115:205-12.
  5. Korting GE, Smith SD, Wheeler MA, et al. A randomized double-blind trial of oral L-arginine for treatment of interstitial cystitis. J Urol 1999;161:558-65. DOI
  6. Rector TS, Bank AJ, Mullen KA, et al. Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure. Circulation 1996;93:2135-41.
  7. Siani A, Pagano E, Iacone R, et al. Blood pressure and metabolic changes during dietary L-arginine supplementation in humans. Am J Hypertens 2000;13:547-51. PubMed
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