Noni Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Noni against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Noni is a dietary supplement by Dynamic Health with 2 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 542 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Certified organic Noni (Morinda citrifolia) juice, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Noni by Dynamic Health
Ask about any prescription or over-the-counter medication and we check it for interactions with Noni by Dynamic Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Noni by Dynamic Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid contains two active ingredients: potassium and certified organic noni juice (Morinda citrifolia). Noni juice is included for its traditional use, though the evidence supporting its effectiveness for most health claims is not yet established in the data we hold.
The product also contains certified organic noni as an inactive ingredient.
Does it work?
Couldn't assess
The evidence we hold does not establish noni's effectiveness for the conditions listed—asthma, atherosclerosis, athletic performance, burns, cancer, and cardiovascular disease all show insufficient reliable evidence to rate. If you're considering this product for a particular health goal, talk with your doctor or pharmacist about whether the evidence supports it and whether it's right for you.
How safe is it?
Well-documented data
Potassium from food is fine, but supplements carry risks—especially for people with kidney disease, who can develop dangerously high blood levels. Use potassium supplements only under medical guidance.
The adverse_effects note that potassium taken by mouth is generally well tolerated, though common side effects include stomach pain, belching, diarrhea, gas, nausea, and vomiting; serious but rare effects include irregular heartbeat, heart block, low blood pressure, and confusion. Noni juice is generally tolerated in moderate amounts, but rare liver injury is a documented concern—several cases of liver failure have been reported, though it's unclear whether noni itself or contaminants were responsible.
The safety data advises against noni during pregnancy, as it has been traditionally used to cause abortion. For breastfeeding, there isn't enough safety information, so check with your doctor or pharmacist before using it.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you're on potassium-sparing water pills (Moderate risk of dangerously high potassium), ACE inhibitors or ARBs for blood pressure (Moderate risk of high potassium), blood thinners like warfarin (Moderate risk of reduced effectiveness), seizure medications like phenytoin (Moderate risk of lower levels and breakthrough seizures), other blood pressure medications (Moderate risk of blood pressure dropping too far), or any drug that stresses your liver (Moderate theoretical risk). Ranitidine users should also check, as noni may raise its levels (Minor concern).
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is potassium-rich and poses real risks if you take water pills, ACE inhibitors, ARBs, blood thinners, or seizure medications—or if you have kidney disease. Even if none of those apply, noni carries a small but serious risk of liver damage.
Talk with your doctor or pharmacist before starting it, especially if you take any medications or have kidney or liver concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Noni, straight from the product label.
| Brand | Dynamic Health |
|---|---|
| Barcode (UPC) | 790223100495 |
| Net contents | 32 Fluid Ounce(s); 946 mL |
| Market status | On market |
| Date entered into DSLD | Sep 24, 2021 |
| DSLD ID | 255321 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Noni by Dynamic Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | -- |
| Potassium | 105 mg | 3% |
| Certified organic Noni (Morinda citrifolia) juice | 100000 mg | -- |
| Calories | 0 Calorie(s) | -- |
Other ingredients: certified organic Noni
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
The fruit of the Noni (Morinda citrifolia) plant has been treasured for hundreds of years by the inhabitants of the exotic islands of Tahiti, the South Pacific and other tropical regions. The warm climate and nutrient rich soil create ideal conditions for these plants to blossom. It has been traditionally used to help promote healthy living.
Noni contains trace amounts of naturally occurring minerals, enzymes, antioxidant vitamins, phytonutrients and bioflavonoids. It is a natural source of proxeronine and scopoletin.
OU (Kosher)
Formulation
Contains no added sugar, artificial color or preservatives.
Certified Organic by Organic Certifiers, Inc.
Gluten free
Vegetarian
Crescent M Halal
Due to the pure, natural ingredients in this product, taste, color and consistency may vary.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Where health & flavor meet!
Recycle
Seals/Symbols
USDA Organic
OU (Kosher)
Crescent M Halal
FDA Statement of Identity
Dietary Supplement
Precautions
Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.
Keep out of reach of children.
Pregnant or breast-feeding women should consult a health care practitioner before using any product.
Suggested/Recommended/Usage/Directions
Directions: Use only as directed. Take 2 TBSP (30 mL) daily or as directed by your health care practitioner. Shake well before using.
Uniquely formulated. Enjoy sipping it pure, adding it to water or your favorite beverage.
Storage
Store in a cool, dry, dark place. Stated levels valid only while product is unopened and properly stored. Refrigerate after opening.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Noni by Dynamic Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Noni by Dynamic Health
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size30 mL Dosage formLiquid Servings per container32 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Potassium
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium monograph & interactionsCertified organic Noni (Morinda citrifolia) juice
Interacts with542 drugs
Noni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claimed benefits...
Certified organic Noni (Morinda citrifolia) juice monograph & interactionsOther (inactive) ingredients: Certified organic Noni. These complete the product’s ingredient list but are not active constituents.
Noni by Dynamic Health Drug Interactions
HelloPharmacist Interaction Report
Noni by Dynamic Health contains potassium and noni juice—both of which interact with medications.
The most serious concern is with potassium-sparing water pills (potassium-sparing diuretics): both ingredients can raise your blood potassium to dangerous levels (hyperkalemia) when combined with these drugs, a Moderate-severity risk.
Read the full breakdown — every affected drug type, severity by severity
Beyond water pills, potassium in this product also poses a Moderate risk with blood pressure medications called ACE inhibitors and ARBs—both work partly by reducing how much potassium your body clears, so adding potassium on top can push levels too high. Noni juice adds its own Moderate interactions with those same blood pressure drugs and water pills, since noni itself is potassium-rich (about 6 mEq per 100 mL).
Additionally, noni juice interacts with several other medication types: it may lower blood pressure further if you're already on antihypertensive drugs, it could interfere with warfarin (a blood thinner) by reducing its effectiveness, it may lower phenytoin (a seizure medication) levels and raise seizure risk, and it might boost ranitidine (an acid reflux drug) to higher-than-intended levels—the last a Minor concern. Noni also theoretically increases risk when combined with medications that stress your liver.
Altogether, these interactions span 543 individual medications.
Check your exact medications with the search tool on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Noni?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Noni interact with 542 drugs. Click any drug to see the details.
2 of the 2 ingredients in Noni interact with drugs. Each result below shows which ingredient is responsible. Certified organic Noni (Morinda citrifolia) juice Potassium
Ammonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Ammonium Chloride interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Amphotericin, Tetracycline interactionAnidulafunginEraxis
How Anidulafungin interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Anidulafungin interactionAprocitentanTryvio
How Aprocitentan interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Aprocitentan interactionAsparaginase Erwinia Chrysanthemi (recombinant)-rywnRylaze
How Asparaginase Erwinia Chrysanthemi (recombinant)-rywn interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Asparaginase Erwinia Chrysanthemi (recombinant)-rywn interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAtenololAtenix, Tenormin
How Atenolol interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Atenolol, Chlorthalidone interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Atorvastatin Calcium interactionAvacopanTavneos
How Avacopan interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Avacopan interactionAzamuneImmunoprin
How Azamune interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Azathioprine interactionAzilsartanEdarbi
How Azilsartan interacts with Noni — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs, Angiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Azilsartan interactionPotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Noni — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAngiotensin Receptor Blockers (arbs), Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining noni and ARBs might increase the risk of hyperkalemia.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Azilsartan, Chlorthalidone interactionPotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Azilsartan, Chlorthalidone interactionBaricitinibOlumiant
How Baricitinib interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Baricitinib interactionBelinostatBeleodaq
How Belinostat interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Belinostat interactionBenazeprilLotensin
How Benazepril interacts with Noni — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAce Inhibitors (aceis), Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining noni and ACE inhibitors might increase the risk of hyperkalemia.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Benazepril interactionPotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Noni — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs, Ace Inhibitors (aceis) Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Benazepril, Hydrochlorothiazide interactionPotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Noni — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuicePotassium-sparing Diuretics Moderate
Interaction Summary
Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Bendroflumethiazide, Potassium interactionPotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Benzhydrocodone, Acetaminophen interactionBenzthiazideExna
How Benzthiazide interacts with Noni — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Noni (morinda Citrifolia) JuiceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Certified Organic Noni (morinda Citrifolia) Juice + Benzthiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Noni with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Certified organic Noni (Morinda citrifolia) juice
Ace Inhibitors (Aceis)
Theoretically, combining noni and ACE inhibitors might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ACE inhibitors, which can also increase potassium levels.
Angiotensin Receptor Blockers (Arbs)
Theoretically, combining noni and ARBs might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ARBs, which can also increase potassium levels.
Antihypertensive Drugs
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Preliminary clinical research suggests that drinking noni juice can reduce blood pressure in individuals with hypertension.
Hepatotoxic Drugs
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
There is concern that noni might cause hepatotoxicity in some patients. Advise patients against combining noni with potentially hepatotoxic drugs.
Phenytoin (Dilantin)
Theoretically, taking noni fruit juice concomitantly with phenytoin may lower phenytoin levels and increase the risk of seizures.
In one case report, an adult taking phenytoin for partial seizures experienced low serum phenytoin levels while taking noni juice 90-200 mL daily. Serum phenytoin levels increased after decreasing noni juice consumption; similarly, serum phenytoin levels decreased after increasing noni juice consumption. Some researchers believe noni juice may induce cytochrome P450 2C9 enzymes, which would decrease phenytoin levels, but this has not been well studied. Patients may need additional monitoring when starting or stopping noni juice supplementation.
Potassium-Sparing Diuretics
Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with potassium-sparing diuretics, which can also increase potassium levels.
Warfarin (Coumadin)
Theoretically, taking noni juice concomitantly with warfarin might decrease the effectiveness of warfarin.
In one case, a 41-year-old patient stabilized on warfarin had a decreased international normalized ratio (INR) following consumption of a specific commercial noni juice product (Noni juice 4 Everything). While the patient was still taking noni juice, an increase in warfarin dose did not produce an increase in INR. However, it should be noted that this particular product contained extracts and derivatives from more than 115 components, many of which contained vitamin K. Furthermore, vitamin K was listed as a separate ingredient of the product, suggesting that the product was possibly fortified with vitamin K. It has not been verified that noni fruit alone contains a significant amount of vitamin K or interacts with warfarin.
Ranitidine (Zantac)
Taking noni fruit with ranitidine might increase the levels and clinical effects of ranitidine.
Clinical evidence shows that taking an aqueous extract of noni fruit 30 minutes prior to taking a single oral dose of ranitidine can increase the rate of absorption and plasma concentration of ranitidine.
Potassium
Ace Inhibitors (Aceis)
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Angiotensin Receptor Blockers (Arbs)
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Potassium-Sparing Diuretics
Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.
Brand information
Manufacturer and brand details for Noni, from the product label.
Dynamic Health
See all Dynamic Health products- Name
- Dynamic Health
- City
- Tulsa
- State
- Oklahoma
- ZipCode
- 74128
- Phone Number
- 800-538-5888
- Web Address
- www.dynamichealth.com
Noni by Dynamic Health: Common Questions
Does Noni by Dynamic Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take noni during pregnancy?
What are the most common side effects?
Is potassium from food okay, or just supplements?
Why does this product have so many drug interactions?
Can noni cause liver problems?
Is there good evidence that noni works for what it's used for?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Noni is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Noni’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Potassium
Interacts with 62 drugsPotassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...
Read the full Potassium monograph → Herb & supplement monographNoni
Interacts with 542 drugsNoni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claimed benefits is limited. While moderate juice intake...
Read the full Noni monograph →Sources & How We Checked
Noni's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Potassium 12 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
- Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
- Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
- Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
- Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
- Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
- Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
- Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
- Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
Noni 16 references
- Mueller BA, Scott MK, Sowinski KM, Prag KA. Noni juice (Morinda citrifolia): hidden potential for hyperkalemia? Am J Kidney Dis 2000;35:310-2. PubMed
- Millonig G, Stadlmann S, Vogel W. Herbal hepatotoxicity: acute hepatitis caused by a Noni preparation (Morinda citrifolia). Eur J Gastroenterol Hepatol 2005;17:445-7. PubMed
- Stadlbauer V, Fickert P, Lackner C, et al. Hepatotoxicity of NONI juice: report of two cases. World J Gastroenterol 2005;11:4758-60. PubMed
- Carr ME, Klotz J, Bergeron M. Coumadin resistance and the vitamin supplement "Noni". Am J Hematol 2004;77:103. PubMed
- Jensen CJ, Westendorf J, Wang MY, Wadsworth DP. Noni juice protects the liver. Eur J Gastroenterol Hepatol 2006;18:575-7. PubMed
- Yuce B, Gulberg V, Diebold J, Gerbes AL. Hepatitis induced by noni juice from morinda citrifolia: a rare cause of hepatotoxicity or the tip of the iceberg? Digestion 2006;73:167-70.
- Koch E, Biber A. Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine 2007;14 Suppl 6:40-5. PubMed
- Yu EL, Sivagnanam M, Ellis L, Huang JS. Acute hepatotoxicity after ingestion of Morinda citrifolia (noni berry) juice in a 14-year-old boy. J Pediatr Gastroenterol Nutr 2011;52:222-4.
- Stadlbauer V, Weiss S, Payer F, Stauber RE. Herbal does not at all mean innocuous: the sixth case of hepatotoxicity associated with morinda citrifolia (noni). Am J Gastroenterol 2008;103:2406-7. PubMed
- López-Cepero Andrada JM, Lerma Castilla S, Fernández Olvera MD, Amaya Vidal A. [Hepatotoxicity caused by a noni (Morinda citrifolia) preparation]. [Article in Spanish] Rev Esp Enferm Dig 2007;99:179-81.
- Nima S, Kasiwong S, Ridtitid W, et al. Gastrokinetic activity of Morinda citrifolia aqueous fruit extract and its possible mechanism of action in human and rat models. J Ethnopharmacol. 2012;142(2):354-61. PubMed
- Issell, B. F., Gotay, C. C., Pagano, I., and Franke, A. A. Using quality of life measures in a Phase I clinical trial of noni in patients with advanced cancer to select a Phase II dose. J.Diet.Suppl 2009;6(4):347-359. PubMed
- Palu AK, Santiago RA West B Kaluhiokalani N Jensen J. The Effects of Morillda citrifolia L. Noni on High Blood Pressure: A Mechanistic Investigation and Case Study. ACS SYMPOSIUM SERIES 993 2008;
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Bussmann RW, Hennig L, Giannis A, Ortwein J, Kutchan TM, Feng X. Anthraquinone Content in Noni (Morinda citrifolia L.). Evid Based Complement Alternat Med. 2013;2013:208378.
- Yu-Chan Kang, Ming-Hong Chen, Shung-Lon Lai. Potentially Unsafe Herb-drug Interactions Between a Commercial Product of Noni Juice and Phenytoin- A Case Report. Acta Neurol Taiwan. 2015 Jun;24(2):43-6.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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