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Dietary supplement

Oil of Oregano Ingredients & Drug Interactions

by BulkSupplements.com

Oil of Oregano label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oil of Oregano against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oil of Oregano is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oil of Oregano. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oil of Oregano by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Oil of Oregano by BulkSupplements.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Oil of Oregano by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: oil of oregano. It's a concentrated extract from the oregano plant, much stronger than the dried herb you'd sprinkle on food.

The softgel also holds soybean oil, gelatin, glycerin, and purified water as inactive ingredients to deliver the oil.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Oregano product and its label doesn't state a use — see Oregano's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have reliable evidence to rate oregano oil for acne, bronchitis, asthma, headache, or upper respiratory tract infections—the conditions often marketed for it. That doesn't mean it doesn't work; it means the clinical data in our files isn't strong enough yet to say one way or the other.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano is well tolerated in food amounts. Concentrated supplements like this one are stronger and haven't been as thoroughly studied, so we're more cautious.

The most common side effect is stomach upset. Rarely, people have had allergic reactions, including severe ones like anaphylaxis, especially if you're sensitive to plants in the mint family (like thyme).

Topical application can irritate skin or mucous membranes in sensitive individuals. During pregnancy, the safety data advises against medicinal or supplement doses; normal food amounts are likely fine.

For breastfeeding, we don't have enough safety information—talk it over with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you're on blood thinners (like warfarin, dabigatran, or aspirin) or diabetes medications (like metformin, insulin, or sulfonylureas). Oregano oil could increase bleeding risk or lower your blood sugar unexpectedly.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Oil of oregano is a single-ingredient supplement generally well tolerated at food doses but less studied at medicinal concentrations. If you take blood thinners or diabetes medication, you'll want to check your exact drugs with your doctor or pharmacist before starting this.

It's not proven to work for common conditions like colds or asthma, so weigh that against the interaction risk in your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oil of Oregano, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X0033QJ3GL
Net contents 300 Softgel(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 294398
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oil of Oregano by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
300
UPC/BARCODE
X0033QJ3GL
IngredientAmount% DV
Oil of Oregano150 mg--

Other ingredients: Soybean Oil, Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Bulk Supplements.com Clean & pure bulk supplements

Formulation

Free of: Added sugar, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 softgel once or twice daily, or as directed by a physician.

Storage

Store in a cool, dry place.

Precautions

Allergen warning: Contains soy

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

New - BulkSupplements.com Oil of Oregano Softgels - Oregano Oil Supplement - Oregano Essential Oil - Oregano Oil 150 mg - Oil of Oregano Capsules - Oregano Oil Essential Oil (300 Count - 300 Servings)

Formula

New - BulkSupplements.com Oil of Oregano Softgels - Oregano Oil Supplement - Oregano Essential Oil - Oregano Oil 150 mg - Oil of Oregano Capsules - Oregano Oil Essential Oil (300 Count - 300 Servings)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oil of Oregano by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oil of Oregano label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oil of Oregano by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container300 Amounts shown are per serving.

Oil of Oregano

Interacts with
208 drugs
150 mg per serving

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oil of Oregano monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oil of Oregano by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Oil of Oregano?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oil of Oregano 208

Individual Drug Interactions

The ingredients in Oil of Oregano interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Oil of Oregano interact with drugs. Each result below shows which ingredient is responsible. Oil of Oregano

Each ingredient & the kinds of drugs it affects

For each ingredient in Oil of Oregano with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oil of Oregano2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oil of Oregano full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oil of Oregano, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Oil of Oregano by BulkSupplements.com: Common Questions

Does Oil of Oregano by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Oil of Oregano has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oil of Oregano contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
The safety data advises against medicinal or supplement amounts during pregnancy. Food amounts of oregano are likely fine, but concentrated supplements are a different story. Talk with your doctor or pharmacist about what's right for you.
What's the most common side effect?
Stomach upset is the most common effect when oregano oil is taken by mouth. Most people tolerate it well, but if your stomach is sensitive, you might notice nausea or discomfort.
Could I have an allergic reaction to oregano?
Yes, though it's rare. Serious allergic reactions, including anaphylaxis, have been reported, especially in people sensitive to plants in the mint family. If you've reacted to thyme or other mint-family herbs, be cautious.
Is this proven to work for colds or respiratory infections?
No—we don't have reliable evidence that oregano oil helps with colds, bronchitis, asthma, or upper respiratory infections. It's often marketed for these uses, but the clinical data isn't there yet to back it up.
How much stronger is this supplement compared to oregano seasoning?
This is a concentrated extract, so it's considerably more potent than the dried herb you'd use in cooking. That's why we're more cautious about its safety and why it interacts with medications in ways food amounts typically wouldn't.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oil of Oregano is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oil of Oregano label
Go deeper

The Full Monographs Behind Oil of Oregano’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oil of Oregano's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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