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Dietary supplement

Oil Of Oregano Ingredients & Drug Interactions

by Planetary Herbals

Oil Of Oregano label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oil Of Oregano against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oil Of Oregano is a dietary supplement by Planetary Herbals with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wildcrafted Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oil Of Oregano by Planetary Herbals

Ask about any prescription or over-the-counter medication and we check it for interactions with Oil Of Oregano by Planetary Herbals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oil Of Oregano by Planetary Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “wildcrafted Oregano Oil” is listed as a grouped ingredient — the label gives one combined amount (45 mg) without saying how much of each component you get.

This product contains one active ingredient: carvacrol, the main compound in oregano oil. The capsule also holds lecithin, modified vegetable cellulose (the capsule material itself), and olive oil as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Oregano product and its label doesn't state a use — see Oregano's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence isn't established. For all the conditions listed on this product—acne, bronchitis, asthma, headache, and upper respiratory tract infection—the data we hold shows insufficient reliable evidence to rate how well oregano works.

That doesn't mean it doesn't work; it means we don't have enough solid research to say either way.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano used in normal food amounts is well tolerated. This supplement is a concentrated form, though, and we have limited safety data on it at those higher doses.

The most common side effect is gastrointestinal upset. Rarely, people have reported allergic reactions, including serious ones like anaphylaxis and swelling of the lips and tongue; allergic contact dermatitis is also possible.

If you've had reactions to other herbs in the mint family (like thyme), mention that to your pharmacist. During pregnancy, the safety data advises against medicinal or supplement amounts—food amounts are likely fine.

While breastfeeding, we don't have enough safety data on supplements, so stick to food amounts and talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before you start if you take blood thinners or antiplatelet drugs—oregano may increase bleeding risk (Moderate severity). Also check if you take diabetes medication—oregano might lower your blood sugar too much (Moderate severity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement might help, but we don't have solid evidence yet for the conditions it lists. If you take blood thinners or diabetes medication, check your exact drugs with the tool on this page before starting.

If you're pregnant, breastfeeding, or have a history of allergies to oregano or mint-family herbs, talk with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oil Of Oregano, straight from the product label.

Brand Planetary Herbals
Barcode (UPC) 021078105046
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 80485
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oil Of Oregano by Planetary Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
021078105046
IngredientAmount% DV
Carvacrol30 mg--
wildcrafted Oregano Oil45 mg--

Other ingredients: Lecithin, Modified Vegetable Cellulose, Olive Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Vegetarian capsules

Approved by Michael Tierra, L.Ac, O.M.D

Planetary Herbals Oil Of Oregano is from wildcrafted true oregano (Origanum vulgare), an aromatic herb that is native to the Mediterranean region. Traditionally, oregano was used to support digestive and respiratory health. In vitro research indicates that carvacrol, an active constituent of oil of oregano, may provide support to the immune system.

Formula

Standardized to 70% Carvacrol

Contains soy.

Planetary Herbals Oil of Oregano is one of the most potent on the market and is standardized to 70% carvacrol.

FDA Statement of Identity

Herbal Supplement

Precautions

Contains soy.

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule 1 to 3 times daily.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Planetary Herbals, LLC

General

PF0504 REV E171-A

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oil Of Oregano by Planetary Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oil Of Oregano label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oil Of Oregano by Planetary Herbals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Wildcrafted Oregano Oil

Interacts with
208 drugs
45 mg per serving

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Wildcrafted Oregano Oil monograph & interactions

Other (inactive) ingredients: Lecithin, Modified Vegetable Cellulose, Olive Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oil Of Oregano by Planetary Herbals Drug Interactions

Want to check YOUR meds against Oil Of Oregano?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

wildcrafted Oregano Oil 208

Individual Drug Interactions

The ingredients in Oil Of Oregano interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Oil Of Oregano interact with drugs. Each result below shows which ingredient is responsible. wildcrafted Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Oil Of Oregano with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
wildcrafted Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oil Of Oregano, from the product label.

Planetary Herbals

See all Planetary Herbals products
Name
Planetary Herbals, LLC
Street Address
P.O. Box 1760
City
Soquel
State
CA
ZipCode
95073
Web Address
www.planetaryherbals.com
Pharmacist Counseling Corner

Oil Of Oregano by Planetary Herbals: Common Questions

Does Oil Of Oregano by Planetary Herbals interact with any medications?
Yes. Based on its ingredients, Oil Of Oregano has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oil Of Oregano contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is oregano oil safe to take while I'm pregnant?
The safety data advises against medicinal or supplement amounts during pregnancy. Food amounts (like using oregano to season dinner) are likely fine. Talk with your doctor or pharmacist about what's right for you.
What side effects does oregano oil cause?
Most commonly, gastrointestinal upset. Rarely, allergic reactions can happen—including serious ones like swelling of the lips and tongue or difficulty breathing. If you've reacted to oregano, thyme, or other mint-family herbs before, let your pharmacist know.
Does this product actually work for bronchitis, asthma, or the other conditions listed?
We don't have enough solid research to say. The evidence for all of them—acne, bronchitis, asthma, headache, and upper respiratory infections—is insufficient to rate right now.
Can I take this if I'm breastfeeding?
We don't have enough safety data on oregano oil supplements while breastfeeding. Stick to food amounts and talk with your doctor or pharmacist for personalized advice.
What is carvacrol?
It's the main active compound in oregano oil. That's what this product contains—a concentrated form of that oregano ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oil Of Oregano is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oil Of Oregano label
Go deeper

The Full Monographs Behind Oil Of Oregano’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oil Of Oregano's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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