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Dietary supplement

Oregano Oil Ingredients & Drug Interactions

by Nutra BioGenesis

Softgel Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Oregano Oil is a dietary supplement by Nutra BioGenesis with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Aerial Oil Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Oregano Oil by Nutra BioGenesis

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: oregano aerial oil extract. It's made from the leaves and stems of the oregano plant and comes concentrated in a softgel capsule.

The softgel also holds gelatin, glycerin, purified water, and extra virgin olive oil as inactive ingredients to keep everything in suspension.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oregano's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Digestive, respiratory and antimicrobial support.
  • We looked for evidence on: Dyspepsia, Upper respiratory tract infection (URTI), Bronchitis, Cough, Intestinal parasite infection, Rhinosinusitis — and 2 related terms.
  • The closest evidence on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Cough, Dyspepsia, Intestinal parasite infection, and more.

The evidence for oregano oil is limited. Our data shows insufficient reliable evidence to rate it for acne, bronchitis, asthma, headache, or upper respiratory tract infection.

That doesn't mean it doesn't work—it means the studies we have aren't robust enough to make a confident claim. If you're thinking about using it for one of these concerns, chat with your pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano is well tolerated in food amounts, but concentrated supplements like this one are much stronger and haven't been studied as thoroughly. The most common side effect is mild stomach upset.

Rarely, some people have had allergic reactions ranging from skin irritation to serious reactions like swelling of the lips and tongue or trouble breathing—especially if you're sensitive to plants in the mint family (Lamiaceae). During pregnancy, avoid medicinal or supplement doses of oregano oil; food amounts are likely fine.

While breastfeeding, we don't have enough safety data on supplements, so stick to food amounts and talk with your doctor or pharmacist if you want to take a supplement.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this product, double-check with your pharmacist if you take blood thinners or antiplatelet drugs (Moderate risk of increased bleeding) or diabetes medications (Moderate risk of low blood sugar). Use the medication search tool on this page to verify your specific prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Oregano oil might be worth trying if you're interested in natural antimicrobial support, but the evidence for specific health claims is thin. If you take blood thinners or diabetes medications, you need to check with your pharmacist first—this product could affect how those drugs work.

Pregnant or breastfeeding? Stick to oregano in your food and skip the supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Oil, straight from the product label.

Brand Nutra BioGenesis
Barcode (UPC) 812806102624
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 323007
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Oil by Nutra BioGenesis, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
812806102624
IngredientAmount% DV
Oregano Aerial Oil Extract57 mg--

Other ingredients: Gelatin, Glycerin, Water, Purified, Extra Virgin Olive Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Non GMO Gluten free

Oregano Oil is designed to help support respiratory health and normal digestive function. Other traditional uses include nutritive support for menstrual comfort, joint health, and urinary tract health.

FDA Statement of Identity

Dietary Supplement

General Statements

Innovative ingredients. Clinical formulations.

Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed healthcare practitioner informed when using this product.

Keep out of reach of children.

Do not use if pregnant or nursing.

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take 1 softgel up to three times daily with meals or as directed by your healthcare practitioner.

Storage

Keep tightly capped and store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Oregano Oil by Nutra BioGenesis label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Oregano Oil by Nutra BioGenesis

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.

Oregano Aerial Oil Extract

Interacts with
208 drugs
57 mg per serving Form: Carvacrol

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano Aerial Oil Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified, Extra Virgin Olive Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Oil by Nutra BioGenesis Drug Interactions

Want to check YOUR meds against Oregano Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Aerial Oil Extract2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Oregano Oil, from the product label.

Nutra BioGenesis

Name
Nutraceutical Corp.
Web Address
www.nutrafamily.com
Pharmacist Counseling Corner

Oregano Oil by Nutra BioGenesis: Common Questions

Does Oregano Oil by Nutra BioGenesis interact with any medications?
Yes. Based on its ingredients, Oregano Oil has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is in this capsule?
One active ingredient: oregano aerial oil extract—the concentrated oil from oregano leaves and stems. The rest is the capsule shell (gelatin and water) and olive oil to keep it dissolved.
Is oregano oil safe if I have a food allergy?
If you're allergic to plants in the mint family—like basil, thyme, or marjoram—oregano oil might trigger a reaction because it's from the same plant family. Even if you've had mild reactions before, a concentrated supplement is stronger than food, so talk to your pharmacist first.
Can I take this while breastfeeding?
The safety data on oregano oil supplements while breastfeeding isn't established. Food amounts of oregano are fine, but we don't have enough information about concentrated supplements. Chat with your doctor or pharmacist about what's right for you.
Does oregano oil actually work for colds or cough?
The evidence we have is insufficient to say for sure. There haven't been enough rigorous studies to confidently claim oregano oil helps with upper respiratory infections, bronchitis, or asthma, so we can't back that claim yet.
What's the most common side effect?
Mild stomach upset when you take it orally. It's usually minor, but if your stomach bothers you easily, start with a lower dose or take it with food.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Oil label
Sources

Sources & How We Checked

Oregano Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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