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Dietary supplement

Oregano Oil Ingredients & Drug Interactions

by NutriCology

Oregano Oil label
See full label image
Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oregano Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oregano Oil is a dietary supplement by NutriCology with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, digestive health and fiber, heart health support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oregano Oil by NutriCology

Ask about any prescription or over-the-counter medication and we check it for interactions with Oregano Oil by NutriCology — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oregano Oil by NutriCology

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: rice bran oil and oregano oil, both supplied as softgel capsules. Rice bran oil is derived from the outer layer of rice grain and is used as a concentrated supplement form.

Oregano oil is a concentrated extract from the oregano herb. The capsules also contain gelatin, glycerin, and water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Dyslipidemia — rated "Possibly Effective" (Rice Bran) (Natural Medicines).

The evidence supporting oregano oil for conditions like acne, bronchitis, asthma, headache, and upper respiratory tract infections is insufficient — we don't have enough reliable data to rate whether it works for these. Rice bran oil shows possibly effective evidence for dyslipidemia (high cholesterol and triglycerides), though the evidence is preliminary.

For other uses of rice bran oil, the evidence is either insufficient or suggests it may be ineffective.

The evidence, ingredient by ingredient Rice Bran Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rice bran oil is generally well tolerated orally, though concentrated supplements have less safety data than food amounts. When you first increase your intake, you may notice temporary abdominal discomfort, bloating, or irregular bowel habits.

Allergic reactions to rice bran are rare but can happen — watch for itching, hives, swelling, or difficulty breathing. Oregano oil is well tolerated in food amounts, but information on larger supplement doses is limited.

Common side effects include mild gastrointestinal upset. Rare but serious allergic reactions, including anaphylaxis, have been reported.

Oregano oil is possibly unsafe during pregnancy in supplement amounts — food amounts are likely fine — so avoid medicinal doses if you're pregnant. Safety during breastfeeding isn't established, so stick to normal food amounts if you're nursing.

Side effects, ingredient by ingredient Rice Bran Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking if you use blood thinners (anticoagulants) or antiplatelet drugs — oregano oil may increase bleeding risk. Also confirm with your doctor or pharmacist if you take diabetes medications, as oregano may lower blood sugar and raise your hypoglycemia risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners or diabetes medications, check with your doctor or pharmacist before starting this product — the interactions are real and could affect how those drugs work. Even if you don't take those medications, note that oregano oil as a supplement is less studied than its use as food seasoning.

This is worth a quick conversation with your own healthcare provider before you add it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Oil, straight from the product label.

Brand NutriCology
Barcode (UPC) 713947538504
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 193246
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Oil by NutriCology, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
713947538504
IngredientAmount% DV
Rice Bran Oil100 mg--
Oregano Oil200 mg--

Other ingredients: Gelatin, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pure essential oil of oregano derived from Origanum vulare, containing 60% carvacrol.

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 1 or 2 softgels daily with meals, or as directed by a healthcare practitioner.

Storage

Keep in a cool, dry place, tightly capped.

General Statements

Innovative Nutrition

Formulation

Hypoallergenic

FDA Statement of Identity

Dietary Supplement

General

Rev. 005

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oregano Oil by NutriCology label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oregano Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oregano Oil by NutriCology

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Rice Bran Oil

No known
interactions
100 mg per serving

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for...

Rice Bran Oil monograph & interactions

Oregano Oil

Interacts with
208 drugs
200 mg per serving Form: Carvacrol

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Oil by NutriCology Drug Interactions

Want to check YOUR meds against Oregano Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano Oil 208

Individual Drug Interactions

The ingredients in Oregano Oil interact with 208 drugs. Click any drug to see the details.

1 of the 2 ingredients in Oregano Oil interact with drugs. Each result below shows which ingredient is responsible. Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oregano Oil, from the product label.

NutriCology

See all NutriCology products
Name
NutriCology
City
Alameda
State
CA
ZipCode
94502
Phone Number
510.263.2000
Web Address
www.nutricology.com
Pharmacist Counseling Corner

Oregano Oil by NutriCology: Common Questions

Does Oregano Oil by NutriCology interact with any medications?
Yes. Based on its ingredients, Oregano Oil has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Oil contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is oregano oil safe to take while pregnant?
The safety data advises against medicinal or supplement amounts of oregano oil during pregnancy. Food amounts — like oregano seasoning in cooking — are likely fine. Since you're pregnant, talk with your doctor or pharmacist before taking this supplement.
What side effects might I notice?
Most commonly, you may feel mild stomach upset or digestive discomfort, especially when you first start or increase the dose. Temporary bloating and irregular bowel habits can also occur with rice bran. Allergic reactions are rare but can include itching, hives, swelling, or trouble breathing — seek immediate care if these happen.
Does oregano oil actually work for colds or respiratory infections?
The evidence we have isn't strong enough yet to say whether oregano oil helps with colds, bronchitis, asthma, or upper respiratory infections. Right now there's insufficient reliable data to rate it for these uses.
Can I take this if I'm breastfeeding?
Safety data for oregano oil supplements while breastfeeding isn't established. Stick to normal food amounts — like oregano seasoning in recipes — rather than concentrated supplements. Ask your doctor or pharmacist what's right for you.
What's rice bran oil doing in an oregano oil product?
Rice bran oil is the carrier or base oil used to deliver the oregano oil in these softgel capsules. It's the medium that allows the active oregano extract to be packaged and absorbed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Oil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Oil label
Go deeper

The Full Monographs Behind Oregano Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rice Bran

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for helping lower cholesterol, but for most...

Read the full Rice Bran monograph → Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oregano Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rice Bran 7 references
  1. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  2. Fujiwaki T, Furusho K. The effects of rice bran broth bathing in patients with atopic dermatitis. Acta Paediatr Jpn 1992;34:505-10.
  3. Uenotsuchi T, Satoh E, Kiryu H, Yano Y. Pyemotes dermatitis caused by indirect contact with husk rice. Br J Dermatol 2000;143:680-2. DOI
  4. Satoh R, Tsuge I, Tokuda R, Teshima R. Analysis of the distribution of rice allergens in brown rice grains and of the allergenicity of products containing rice bran. Food Chem. 2019;276:761-767. PubMed
  5. Togashi Y, Inomata N, Suzuki A, Hakuta A, Aihara M. Pediatric case with rice bran allergy induced by epicutaneous sensitization in a family rice shop. Allergol Int. 2019;68(1):117-118. PubMed
  6. So WKW, Chan JYW, Law BMH, et al. Effects of a Rice Bran Dietary Intervention on the Composition of the Intestinal Microbiota of Adults with a High Risk of Colorectal Cancer: A Pilot Randomised-Controlled Trial. Nutrients 2021;13(2):526. PubMed
  7. Haneda Y, Kadowaki S, Furui M, Taketani T. A pediatric case of food-dependent exercise-induced anaphylaxis due to rice bran. Asia Pac Allergy 2021;11(1):e4. PubMed

See these in context on the Rice Bran monograph →

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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