Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Oregano Oil Ingredients & Drug Interactions

by Vitality Works

Oregano Oil label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oregano Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oregano Oil is a dietary supplement by Vitality Works with 2 active ingredients. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oregano Oil by Vitality Works

Ask about any prescription or over-the-counter medication and we check it for interactions with Oregano Oil by Vitality Works — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oregano Oil by Vitality Works

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.
  • “Oregano Oil” is listed as a grouped ingredient — the label gives one combined amount (43 mg) without saying how much of each component you get.

This liquid supplement contains 2 active ingredients: carvacrol and wild Mediterranean oregano oil, both concentrated forms of oregano extract. It's suspended in extra virgin olive oil as an inactive carrier.

Concentrated oregano oil is much stronger than the dried herb you'd use in cooking. That's why the safety profile shifts when you move from food amounts to supplement doses—there's simply less research on how the concentrated form behaves in your body.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Oregano product and its label doesn't state a use — see Oregano's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for oregano oil isn't established yet in the data we hold. The supplement has been studied for acne, bronchitis, asthma, headache, and upper respiratory tract infections, but each of those carries a rating of insufficient reliable evidence to say whether it works.

That doesn't mean it doesn't work—it means we don't have solid clinical proof one way or the other.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano is well tolerated in normal food amounts. As a concentrated supplement, though, there's limited safety information available.

The most common side effect is gastrointestinal upset. Topically, it can cause dermatitis (skin irritation) in sensitive people, especially at concentrations above 1%.

Rarely, people have had systemic allergic reactions, including anaphylaxis—one documented case involved a man who developed swelling, breathing trouble, and low blood pressure after eating oregano-seasoned food. During pregnancy, avoid medicinal or supplement doses; food amounts are likely fine.

While breastfeeding, stick to normal food amounts—safety of supplements isn't established. If you have allergies to plants in the mint family (Lamiaceae), mention that to your doctor or pharmacist before trying this.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Vitality Works Oregano Oil, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel)—oregano may increase bleeding risk. Also flag any diabetes medications you take, since oregano might lower blood sugar further.

Use the medication checker on this page to run through your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Oregano oil supplement might appeal to you if you're interested in herbal antimicrobial support, but the evidence for specific uses isn't solid yet. If you take blood thinners, diabetes medications, or have a history of allergies to oregano or related herbs, talk with your doctor or pharmacist before starting.

Pregnant or breastfeeding? Check with your healthcare provider first, since concentrated oregano oil hasn't been well studied in those settings.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Oil, straight from the product label.

Brand Vitality Works
Barcode (UPC) 788332036811
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246488
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Oil by Vitality Works, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
4 Drop(s)
Servings per container
270
UPC/BARCODE
788332036811
IngredientAmount% DV
Carvacrol30 mg--
Oregano Oil43 mg--
Wild Mediterranean Oregano Oil0 NP--

Other ingredients: extra virgin Olive Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Internally, 1-4 drops, 2-3 times daily. May be diluted in water. Externally, apply liberally as needed.

Shake well before using.

Precautions

Warning: Please keep out of the reach of children.

A normal warming sensation may be noticed when applied externally. Avoid contact with genitals.

FDA Statement of Identity

Herbal supplement

Seals/Symbols

KOF-K Parve (Kosher) K-1604

Formula

KOF-K Parve (Kosher) K-1604

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oregano Oil by Vitality Works label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oregano Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oregano Oil by Vitality Works

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container270 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Oregano Oil

Interacts with
208 drugs
43 mg per serving

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano Oil monograph & interactions

Wild Mediterranean Oregano Oil

Interacts with
208 drugs
0 NP per serving Form: Carvacrol

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Wild Mediterranean Oregano Oil monograph & interactions

Other (inactive) ingredients: Extra virgin Olive Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Oil by Vitality Works Drug Interactions

Want to check YOUR meds against Oregano Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano Oil 208

Individual Drug Interactions

The ingredients in Oregano Oil interact with 208 drugs. Click any drug to see the details.

1 of the 2 ingredients in Oregano Oil interact with drugs. Each result below shows which ingredient is responsible. Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oregano Oil, from the product label.

Vitality Works

See all Vitality Works products
Name
Vitality Works, Inc.
Street Address
8500 Bluewater Rd. NW
City
Albuquerque
State
NM
ZipCode
87121
Pharmacist Counseling Corner

Oregano Oil by Vitality Works: Common Questions

Does Oregano Oil by Vitality Works interact with any medications?
Yes. Based on its ingredients, Oregano Oil has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Oil contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
The safety data advises against medicinal or supplement amounts of oregano during pregnancy. Food amounts are likely fine, but talk with your doctor or pharmacist about whether this supplement is right for you.
What's the difference between this supplement and oregano I cook with?
This is a concentrated liquid extract—much stronger than dried herb. Oregano in food is generally well tolerated, but we know less about how concentrated supplements behave in your body at higher doses.
What are the side effects?
The most common is stomach upset. Topically, it can irritate skin in sensitive people. Serious allergic reactions are rare but have been reported, especially in people allergic to the mint family of plants.
Does oregano oil actually work for colds or respiratory infections?
It's been studied for upper respiratory infections, asthma, and bronchitis, but we don't have enough reliable evidence to say whether it works for any of those. The evidence rating is insufficient right now.
Is it safe to use while breastfeeding?
There isn't enough data to know either way. Stick to normal food amounts if you're breastfeeding, and talk with your doctor or pharmacist about whether the supplement is safe for you.
What if I'm allergic to oregano or related herbs?
Oregano is in the mint family, and allergic reactions have been reported. If you've had reactions to oregano, thyme, or other herbs in that family, mention it to your doctor or pharmacist before taking this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Oil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Oil label
Go deeper

The Full Monographs Behind Oregano Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oregano Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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