Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Oregano Oil & Olive Leaf Ingredients & Drug Interactions

by LifeTIME

Oregano Oil & Olive Leaf label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oregano Oil & Olive Leaf against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oregano Oil & Olive Leaf is a dietary supplement by LifeTIME with 3 active ingredients. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Oil Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Oregano Oil & Olive Leaf by LifeTIME

Ask about any prescription or over-the-counter medication and we check it for interactions with Oregano Oil & Olive Leaf by LifeTIME — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Oregano Oil & Olive Leaf by LifeTIME

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (600 mg) without saying how much of each component you get.

This liquid contains three active ingredients: a proprietary blend (whose components are broken out separately), olive leaf extract, and olive. Olive has been used traditionally for various conditions, though the evidence for most uses isn't well established in the data we hold.

Oregano oil extract is the ingredient driving potential drug interactions here. The product also contains grain alcohol and deionized water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we have for what this product actually does is limited. Both olive leaf extract and olive are listed for conditions like osteoporosis, heartburn (dyspepsia), shingles, flu, and arthritis—but for all of these, the reliable evidence is insufficient to rate them.

Oregano oil extract is similarly listed for acne, bronchitis, asthma, headache, and upper respiratory infection, but again, the evidence isn't established in the data we hold. If you're considering this for a specific health concern, your doctor or pharmacist can help you weigh what's known.

The evidence, ingredient by ingredient Olive Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive leaf extract and olive are generally well tolerated when used in typical amounts—headache and stomach discomfort are the most common side effects reported. A small number of people have reported skin or acne issues.

Oregano oil is well tolerated in food amounts, but concentrated supplements are less studied. The most common side effect is gastrointestinal upset.

Topically, oregano oil can cause skin irritation or dermatitis in sensitive people. Rarely, oregano has triggered systemic allergic reactions, including anaphylaxis—if you notice any signs of allergy (difficulty breathing, swelling of lips or tongue, sudden drop in blood pressure), stop immediately and seek help.

The safety data advises against oregano oil in medicinal amounts during pregnancy; food amounts are likely fine. While breastfeeding, stick to normal food amounts—safety of supplements isn't established.

Side effects, ingredient by ingredient Olive Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, clear it with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin)—oregano oil may raise your bleeding risk. Also double-check if you take diabetes medications, since oregano may lower blood sugar and could push levels too low.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is best suited for someone looking for a traditional herbal blend who doesn't take blood thinners, antiplatelet drugs, or diabetes medications. If you take any prescription drugs—especially those for blood clotting or blood sugar—talk with your doctor or pharmacist before starting.

Concentrated oregano oil is less studied than the food form, so it's worth a quick check-in about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Oil & Olive Leaf, straight from the product label.

Brand LifeTIME
Barcode (UPC) 053232788543
Net contents 2 Fluid Ounce(s); 59 Milliliter(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 268458
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Oil & Olive Leaf by LifeTIME, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
59
UPC/BARCODE
053232788543
IngredientAmount% DV
Proprietary Blend600 mg--
Olive Leaf Extract0 NP--
Olive0 NP--
Oregano Oil Extract0 NP--

Other ingredients: Grain Alcohol, deionized Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Premium Quality

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.

Keep out of reach of children.

Do not use if you are pregnant or nursing.

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take 30 drops directly, or mix in a small amount of water or juice, up to 3 times daily.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oregano Oil & Olive Leaf by LifeTIME label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oregano Oil & Olive Leaf label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oregano Oil & Olive Leaf by LifeTIME

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container59 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

600 mg per serving

Other (inactive) ingredients: Grain Alcohol, Deionized Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Oil & Olive Leaf by LifeTIME Drug Interactions

Want to check YOUR meds against Oregano Oil & Olive Leaf?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano Oil Extract 208

Individual Drug Interactions

The ingredients in Oregano Oil & Olive Leaf interact with 208 drugs. Click any drug to see the details.

1 of the 3 ingredients in Oregano Oil & Olive Leaf interact with drugs. Each result below shows which ingredient is responsible. Oregano Oil Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Oil & Olive Leaf with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Oil Extract2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano Oil Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oregano Oil & Olive Leaf, from the product label.

LifeTIME

Name
LifeTime Vitamins
City
San Clemente
State
CA
ZipCode
92672
Phone Number
(800) 333-6168
Web Address
www.lifetimevitamins.com
Pharmacist Counseling Corner

Oregano Oil & Olive Leaf by LifeTIME: Common Questions

Does Oregano Oil & Olive Leaf by LifeTIME interact with any medications?
Yes. Based on its ingredients, Oregano Oil & Olive Leaf has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Oil & Olive Leaf contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant or breastfeeding?
The oregano oil in this product is rated possibly unsafe in medicinal amounts during pregnancy—food amounts of oregano are likely fine, but the concentrated supplement form is a different story. While breastfeeding, safety of the supplement isn't established, so stick to normal food amounts. Talk with your doctor about whether this product is right for you right now.
What's the most common side effect I might notice?
Stomach upset is the most common side effect reported with oregano oil. Olive extract may cause headache or stomach discomfort. A small number of people have also reported skin issues or acne with olive products.
Can I have an allergic reaction to oregano oil?
Yes, though it's rare. Most people do well, but oregano has triggered systemic allergic reactions in sensitive individuals, including anaphylaxis in one documented case. If you notice difficulty breathing, swelling of the lips or tongue, or a sudden drop in blood pressure, stop and get help immediately.
Does this actually work for colds or other infections?
Both oregano and olive are listed for conditions like upper respiratory infections and flu, but the reliable evidence to support those uses isn't established in the data we hold. Your doctor can discuss whether this product makes sense for what you're dealing with.
Why does the label say to avoid this during pregnancy if oregano is just a food seasoning?
Oregano as a food seasoning in normal amounts is fine, but this product is a concentrated supplement—it's a much stronger dose. The safety data on concentrated oregano oil in pregnancy is limited, so the caution applies to the supplement form, not to oregano in your cooking.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Oil & Olive Leaf is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Oil & Olive Leaf label
Go deeper

The Full Monographs Behind Oregano Oil & Olive Leaf’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Olive

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...

Read the full Olive monograph → Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oregano Oil & Olive Leaf's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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