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Dietary supplement

Oregano Spirits Whole Leaf Extract & Essential Oil Ingredients & Drug Interactions

by Herb Pharm

Oregano Spirits Whole Leaf Extract & Essential Oil label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oregano Spirits Whole Leaf Extract & Essential Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oregano Spirits Whole Leaf Extract & Essential Oil is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Spirits(TM). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product is a single-ingredient extract: oregano, delivered as a liquid spirits formulation that combines whole leaf extract with essential oil. It's suspended in certified organic grain alcohol and distilled water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Oregano product and its label doesn't state a use — see Oregano's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for oregano as a medicine isn't established in the data we hold. It's been studied for acne, bronchitis, asthma, headache, and upper respiratory tract infections, but reliable evidence to rate it as effective for any of these is currently insufficient.

It's used as a culinary herb, but that's different from its use as a supplement for treating illness.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When oregano is eaten in normal food amounts, it's well tolerated — mostly just occasional stomach upset. The safety data here advises against taking supplement amounts during pregnancy, though food-level oregano is likely fine.

For breastfeeding, there isn't enough data to know whether supplement amounts are safe, so talk with your doctor or pharmacist about it. A small number of people are allergic to oregano and related plants in the mint family; in rare cases, this can cause serious allergic reactions including anaphylaxis.

Topically, oregano oil at concentrations above 1% can irritate mucous membranes and skin in sensitive individuals.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this oregano extract, check it with your doctor or pharmacist if you take blood thinners or diabetes medications. Both are Moderate-severity concerns.

Altogether, these interactions span 208 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is best for people who've used oregano in cooking and want to try a concentrated supplement — but only after checking it against their current medications, especially blood thinners and diabetes drugs. If you take any prescription medicine, run it through our tool first, and talk it over with your doctor or pharmacist before you start.

Skip it during pregnancy unless you're using normal food amounts.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Spirits Whole Leaf Extract & Essential Oil, straight from the product label.

Brand Herb Pharm
Net contents 8 fl. Oz.
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 24236
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
IngredientAmount% DV
Oregano Spirits(TM)0 NP--

Other ingredients: Certified organic grain alcohol, distilled Water, Oregano Essential Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Oregano Spirits(TM) is a blend of the plant extract and the essential oil of Origanum vulgare plants.

The extract is made from Certified Organically Grown plants and the essential oil is distilled from plants that are Custom Wildcrafted(TM) in their natural wild habitat in the mountains of Turkey.

General Statements

To assure optimal potency, flavor and aroma, the cultivated and wildcrafted Oregano plants are hand-harvested as they are flowering and are then carefully shade-dried. The essential oil is steam-distilled (solvents are never used). Our Oregano is never fumigated or irradiated.

LIQUID HERBAL EXTRACT

401425-1W36

FDA Statement of Identity

HERBAL DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

SUGGESTED USE Shake Well Before Using Two to four times per day take 20 to 30 drops in 4 ounces of water.

Shake Well Before Dispensing From This Bottle

Precautions

Do not take drops undiluted.

Consult expert medical advice before taking during pregnancy.

Keep Out of the Reach of Children

General

006

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oregano Spirits Whole Leaf Extract & Essential Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Oregano Spirits(TM)

Interacts with
208 drugs
0 NP per serving

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano Spirits(TM) monograph & interactions

Other (inactive) ingredients: Certified organic grain alcohol, Distilled Water, Oregano Essential Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm Drug Interactions

Want to check YOUR meds against Oregano Spirits Whole Leaf Extract & Essential Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano Spirits(TM) 208

Individual Drug Interactions

The ingredients in Oregano Spirits Whole Leaf Extract & Essential Oil interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Oregano Spirits Whole Leaf Extract & Essential Oil interact with drugs. Each result below shows which ingredient is responsible. Oregano Spirits(TM)

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Spirits Whole Leaf Extract & Essential Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Spirits(TM)2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano Spirits(TM) full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oregano Spirits Whole Leaf Extract & Essential Oil, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm: Common Questions

Does Oregano Spirits Whole Leaf Extract & Essential Oil by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Oregano Spirits Whole Leaf Extract & Essential Oil has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Spirits Whole Leaf Extract & Essential Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is oregano safe during pregnancy?
The safety data advises against medicinal or supplement amounts during pregnancy. Normal food amounts are likely fine. Because this is a concentrated extract, talk with your doctor or pharmacist about whether it's right for you.
Can I take this if I'm breastfeeding?
There isn't enough data to know whether this supplement is safe while breastfeeding. Stick to normal food amounts, and ask your doctor or pharmacist whether a concentrated oregano supplement is okay for you.
Does oregano actually work for colds or bronchitis?
The evidence isn't established in our data. Oregano is studied for upper respiratory infections and bronchitis, but we don't have reliable evidence yet that it's effective for those uses.
What side effects might I see?
When used in food amounts, oregano is well tolerated, though some people get stomach upset. The safety of larger supplement amounts is less clear. Rarely, people allergic to oregano or related plants can have serious allergic reactions. If you apply oregano oil to skin or mucous membranes, it may cause irritation or dermatitis in sensitive people.
What's actually in this liquid?
It's oregano extract and oregano essential oil suspended in certified organic grain alcohol and distilled water. Grain alcohol is the carrier — it helps preserve the extract and keeps the essential oil in solution.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Spirits Whole Leaf Extract & Essential Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Spirits Whole Leaf Extract & Essential Oil label
Go deeper

The Full Monographs Behind Oregano Spirits Whole Leaf Extract & Essential Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oregano Spirits Whole Leaf Extract & Essential Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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