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Dietary supplement

Oreganol Ingredients & Drug Interactions

by Purity Products

Oreganol label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oreganol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oreganol is a dietary supplement by Purity Products with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wild Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oreganol by Purity Products

Ask about any prescription or over-the-counter medication and we check it for interactions with Oreganol by Purity Products — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oreganol by Purity Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (140 mg) without saying how much of each component you get.

Oreganol is a single-ingredient supplement: wild oregano oil delivered in a softgel capsule. The oregano oil is supplied as a proprietary blend, meaning the exact processing and concentration aren't spelled out on the label.

That's important to know, because the strength of oregano oil supplements varies widely — they're much more concentrated than the oregano you'd sprinkle on pizza.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oregano's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune system support.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Bronchitis, Cough, Rhinosinusitis, Intestinal parasite infection, Cold and flu support — and 2 related terms.
  • The closest evidence on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Cough, Intestinal parasite infection, Rhinosinusitis.

The evidence for oregano oil as medicine hasn't been established in our data. The supplement is marketed for acne, bronchitis, asthma, headache, and upper respiratory tract infections, but studies to date are insufficient to rate whether it actually works for any of those uses.

That doesn't mean it doesn't work — it means the reliable research isn't there yet.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano as a food is well tolerated. When you take it as a concentrated supplement, though, the safety picture changes: we have less research and more unknowns.

The most common side effect reported is gastrointestinal upset — nausea, cramping, or digestive discomfort. Topically (applied to skin), oregano oil can cause dermatitis in sensitive people, especially at concentrations above 1%.

Rarely, some people have had allergic reactions, including serious ones like anaphylaxis; one documented case involved a man who developed swelling, breathing difficulty, and low blood pressure after eating oregano-seasoned food. If you have a known allergy to oregano or other plants in the mint family (like thyme), this product isn't for you.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Oreganol, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin) — oregano oil may increase bleeding risk. Also flag it if you're on diabetes medications, since it might lower blood sugar further.

These are the drug types where we've documented Moderate-severity interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Oreganol is a straightforward oregano oil supplement, but it's not a casual add-on if you take blood thinners, antiplatelet drugs, or diabetes medications — those need a conversation with your doctor or pharmacist first. It's also one to skip or discuss if you're pregnant or breastfeeding.

If you don't fall into those categories and want to try it, know that the evidence it works for its marketed uses isn't established yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oreganol, straight from the product label.

Brand Purity Products
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243966
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oreganol by Purity Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
IngredientAmount% DV
Proprietary Blend140 mg--
wild Oregano Oil0 NP--

Other ingredients: Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

North American Herb & spice

Immune system support P73

Capsules made form 100% beef gelatin (BSE-free) non-GMO

General Statements

Power of nature

Formula

Oil of wild oregano

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oreganol by Purity Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oreganol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oreganol by Purity Products

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Proprietary Blend

140 mg per serving Form: extra virgin Olive Oil

Other (inactive) ingredients: Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oreganol by Purity Products Drug Interactions

Want to check YOUR meds against Oreganol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

wild Oregano Oil 208

Individual Drug Interactions

The ingredients in Oreganol interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Oreganol interact with drugs. Each result below shows which ingredient is responsible. wild Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Oreganol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wild Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
wild Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oreganol, from the product label.

Purity Products

See all Purity Products products
Name
Purity Products
Pharmacist Counseling Corner

Oreganol by Purity Products: Common Questions

Does Oreganol by Purity Products interact with any medications?
Yes. Based on its ingredients, Oreganol has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oreganol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does oregano oil actually work for colds or respiratory infections?
The evidence isn't established in our data. Oregano oil is marketed for bronchitis, asthma, and upper respiratory infections, but reliable studies showing it actually works for these aren't on file. That doesn't mean it can't help — just that we don't have the research to say either way yet.
Will oregano oil upset my stomach?
Gastrointestinal upset is the most commonly reported side effect when people take oregano oil as a supplement. It's generally well tolerated, but some folks experience nausea or digestive discomfort — especially at higher doses or on an empty stomach.
Is oregano oil the same thing as oregano seasoning?
No — they're very different. Food-grade oregano seasoning is mild and safe in normal amounts. This supplement is a concentrated oil that's much stronger and less studied at high doses. That's why it carries more cautions.
Can I take this if I'm allergic to the mint family?
No. Oregano belongs to the mint family (Lamiaceae), and people with allergies to thyme or other mint-family plants have had serious allergic reactions to oregano. If that's you, skip this product.
What happens if I take oregano oil with my blood thinner?
Lab research suggests oregano oil may affect how blood clots, potentially increasing bleeding risk when combined with drugs like warfarin or aspirin. This is a Moderate-severity concern, so don't combine them without your doctor's okay.
Can oregano oil make my blood sugar drop too low?
Yes, theoretically. Animal and lab studies suggest oregano extracts might lower blood glucose, so if you're already on a diabetes medication, adding this supplement could push your blood sugar too low. Check with your doctor or pharmacist before taking it together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oreganol label
Go deeper

The Full Monographs Behind Oreganol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oreganol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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