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Dietary supplement

Oreganol P73 Ingredients & Drug Interactions

by North American Herb & Spice

Oreganol P73 label
See full label image
Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oreganol P73 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oreganol P73 is a dietary supplement by North American Herb & Spice with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wild Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oreganol P73 by North American Herb & Spice

Ask about any prescription or over-the-counter medication and we check it for interactions with Oreganol P73 by North American Herb & Spice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oreganol P73 by North American Herb & Spice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (140 mg) without saying how much of each component you get.

Oreganol P73 is a one-ingredient product: wild oregano oil in a softgel capsule. Oregano oil is the concentrated extract of the oregano plant and is much stronger than the oregano you'd sprinkle on pizza.

The capsule itself is made from BSE-free beef gelatin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Oregano product and its label doesn't state a use — see Oregano's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for oregano oil isn't yet established for any of the uses listed in the data—acne, bronchitis, asthma, headache, and upper respiratory tract infection all have insufficient reliable evidence to rate. That doesn't mean it doesn't work; it means larger, well-designed studies haven't been done yet to prove or disprove benefit.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano in food amounts is generally well tolerated. When used as a concentrated supplement, the safety picture is less clear because it's much stronger and less studied than food amounts.

Gastrointestinal upset is the most common side effect when taken by mouth. Rare but serious allergic reactions, including anaphylaxis, have been reported in sensitive individuals.

For pregnancy, the safety data advises against medicinal or supplement doses, though food amounts are likely fine. For breastfeeding, there isn't enough data to know whether supplement amounts are safe—talk with your doctor or pharmacist for personalized advice.

If you have a known allergy to oregano or other plants in the mint family (Lamiaceae), you should avoid this product.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take blood thinners (anticoagulants) like warfarin or apixaban, or diabetes medications like metformin or insulin. Oregano oil may increase bleeding risk and lower blood sugar, changing how these drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Oreganol P73 is one to check before you start if you take blood thinners or diabetes medications. Evidence for its effectiveness isn't yet established in reliable studies.

If you're pregnant or breastfeeding, or if you have a history of allergic reactions to oregano or mint-family plants, talk with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oreganol P73, straight from the product label.

Brand North American Herb & Spice
Barcode (UPC) 635824006916
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Oct 25, 2018
DSLD ID 182085
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oreganol P73 by North American Herb & Spice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
120
UPC/BARCODE
635824006916
IngredientAmount% DV
wild Oregano Oil0 NP--
Proprietary Blend140 mg--

Other ingredients: BSE-free Beef Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one capsule daily with meals or juice or on an empty stomach.

Only this premium product can be taken every day.

Formula

Known for hundreds of uses, Oreganol P73 is the original, edible, guaranteed wild oregano oil blend. Each P73 gelcap contains six drops of the finest high-mountain oregano oil blend. Mediterranean wild Oreganol P73 is made with the highest quality materials and cGMP standards.

Oil of Wild Oregano

Mediterranean source P73

General Statements

Every handpicked harvest is tested for purity and authenticity.

Healthy immune support

4 month’s supply Box-free, save a tree

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Guaranteed wild non-GMO

Non-GMO, soy-free

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oreganol P73 by North American Herb & Spice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oreganol P73 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oreganol P73 by North American Herb & Spice

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.

Proprietary Blend

140 mg per serving Form: certified organic e.v. Olive Oil

Other (inactive) ingredients: BSE-free Beef Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oreganol P73 by North American Herb & Spice Drug Interactions

Want to check YOUR meds against Oreganol P73?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

wild Oregano Oil 208

Individual Drug Interactions

The ingredients in Oreganol P73 interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Oreganol P73 interact with drugs. Each result below shows which ingredient is responsible. wild Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Oreganol P73 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wild Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
wild Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oreganol P73, from the product label.

North American Herb & Spice

See all North American Herb & Spice products
Name
North American Herb & Spice
Street Address
13900 W. Polo Trail Drive
City
Lake Forest
State
IL
ZipCode
60045
Phone Number
1-800-243-5242
Web Address
www.oreganol.com
Pharmacist Counseling Corner

Oreganol P73 by North American Herb & Spice: Common Questions

Does Oreganol P73 by North American Herb & Spice interact with any medications?
Yes. Based on its ingredients, Oreganol P73 has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oreganol P73 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is oregano oil the same as oregano seasoning?
No. Oregano oil is a concentrated extract that's much stronger than the dried herb you'd use in cooking. Because it's so concentrated, its effects and safety profile aren't as well understood as food amounts.
Can I take this if I'm pregnant?
Medicinal or supplement doses of oregano oil are not advised during pregnancy, though the oregano you eat as food is considered fine. If you're thinking about taking this supplement while pregnant, talk with your doctor or pharmacist for personalized guidance.
What's the most common side effect?
Gastrointestinal upset—stomach discomfort or digestive issues—is the most common side effect reported when oregano is taken by mouth in supplement form.
Are there any serious risks?
Serious allergic reactions, including anaphylaxis, have been rarely reported in sensitive individuals. If you've had allergies to oregano, thyme, or other mint-family plants, you should avoid this product.
Does oregano oil actually work for colds or bronchitis?
There isn't enough reliable evidence yet to say whether it works for upper respiratory infections, bronchitis, or asthma. Larger studies would be needed to know for sure.
What's in the capsule besides the oregano oil?
The capsule itself is made from BSE-free beef gelatin, which is an inactive ingredient that holds the oil.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oreganol P73 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oreganol P73 label
Go deeper

The Full Monographs Behind Oreganol P73’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oreganol P73's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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