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Dietary supplement

Organic Holy Basil Ingredients & Drug Interactions

by Five Flavors Herbs

Organic Holy Basil label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Holy Basil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Holy Basil is a dietary supplement by Five Flavors Herbs with 1 active ingredient. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Holy Basil Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Holy Basil by Five Flavors Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Holy Basil by Five Flavors Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Holy Basil by Five Flavors Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid contains one active ingredient: holy basil aerial parts extract. Holy basil is an herb traditionally used to support stress and overall wellness.

The product also contains cane alcohol and purified water as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Holy Basil's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Adaptogenic mood support.
  • We looked for evidence on: Stress, Generalized anxiety disorder (GAD), Insomnia, Anxiety, Mental wellbeing.
  • The closest evidence on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD) (Natural Medicines).
  • Also on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Stress.

The evidence for holy basil isn't established yet in the data we hold. Our sources rate it as having insufficient reliable evidence for generalized anxiety disorder, asthma, headache, respiratory tract infections, dental plaque, and diabetes — meaning the studies done so far are too small or limited to be confident about whether it works for these uses.

The evidence, ingredient by ingredient Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holy basil extract is generally well tolerated short-term in adults, though long-term safety data are sparse. The most common side effects from oral use are loose stools and nausea — a small number of trial participants reported these.

Topical use (like mouthwash) can cause a bitter taste. Because of animal data raising concerns, the safety data advises against use during pregnancy and while breastfeeding — talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check whether you take blood thinners or antiplatelet drugs (Moderate severity), diabetes medications (Moderate), or pentobarbital or other sedatives (Moderate). These are the main drug types holy basil may affect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Holy basil may be worth considering if you're looking for a traditional herbal support and you don't take blood thinners, diabetes medications, or sedatives. If you're on any of those, or any other prescription medication, check it against this product first.

Pregnant or breastfeeding? Skip it — the data aren't there yet to say it's safe.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Holy Basil, straight from the product label.

Brand Five Flavors Herbs
Barcode (UPC) 635983568805
Net contents 2 Fluid Ounce(s); 59 mL
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 320700
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Holy Basil by Five Flavors Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Milliliter(s)
Maximum serving Sizes:
1 Milliliter(s)
Servings per container
59
UPC/BARCODE
635983568805
IngredientAmount% DV
Holy Basil Aerial Parts Extract1 mL--

Other ingredients: Cane Alcohol, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use 1 ml, 2 -3 times daily in water, or as directed. Shake well before using.

Precautions

Caution Consult your physician or qualified herbalist before using if pregnant or nursing.

Keep out of reach of children.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Integrating Traditions for Wellness Five Flavors Herbs creates and delivers effective, sustainable herbal remedies by integrating East Asian medicine principles with Western herbs and modern research. Adaptogenic mood support

USDA Organic Certified Organic by CCOF

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Holy Basil by Five Flavors Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Holy Basil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Holy Basil by Five Flavors Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Milliliter(s) Dosage formLiquid Servings per container59 Amounts shown are per serving.

Holy Basil Aerial Parts Extract

Interacts with
212 drugs
1 mL per serving

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Holy Basil Aerial Parts Extract monograph & interactions

Other (inactive) ingredients: Cane Alcohol, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Holy Basil by Five Flavors Herbs Drug Interactions

Want to check YOUR meds against Organic Holy Basil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Holy Basil Aerial Parts Extract 212

Individual Drug Interactions

The ingredients in Organic Holy Basil interact with 212 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Holy Basil interact with drugs. Each result below shows which ingredient is responsible. Holy Basil Aerial Parts Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Holy Basil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Holy Basil Aerial Parts Extract3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Holy Basil Aerial Parts Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Holy Basil, from the product label.

Five Flavors Herbs

See all Five Flavors Herbs products
Name
Five Flavors Herbs, Inc.
Street Address
344 40th St.
City
Oakland
State
CA
ZipCode
94609
Web Address
www,fiveflavorsherbs.com
Pharmacist Counseling Corner

Organic Holy Basil by Five Flavors Herbs: Common Questions

Does Organic Holy Basil by Five Flavors Herbs interact with any medications?
Yes. Based on its ingredients, Organic Holy Basil has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Holy Basil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's in this liquid?
It's holy basil aerial parts extract — the leaves, stems, and flowers of the plant — mixed with cane alcohol and purified water. That's it; one active ingredient.
Does holy basil work for anxiety or stress?
The evidence isn't strong enough yet to say for sure. Our data rate it as insufficient evidence for generalized anxiety disorder and several other conditions. Smaller or older studies have suggested it might help, but we need bigger, better trials.
What side effects should I watch for?
Loose stools and nausea are the most common ones people report when taking it by mouth. They were mild and infrequent in the trials we have. If you use it as a mouthwash, it may taste bitter.
Is it safe to take while I'm pregnant or breastfeeding?
No — the safety data advise against it in both pregnancy and breastfeeding. Talk with your doctor or pharmacist about your options if you're in either situation.
Can I take this with my blood pressure or blood sugar medication?
Check with your pharmacist first. Holy basil may lower blood sugar and could affect how blood clots form, so you need to verify it's safe with your specific drugs before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Holy Basil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Holy Basil label
Go deeper

The Full Monographs Behind Organic Holy Basil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Organic Holy Basil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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