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Dietary supplement

Organic Nettle Leaf Ingredients & Drug Interactions

by Traditional Medicinals

Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Organic Nettle Leaf is a dietary supplement by Traditional Medicinals with 1 active ingredient. Its ingredients are commonly taken for enlarged prostate (bph) symptoms, seasonal allergies, joint pain and arthritis.Based on those ingredients, 164 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stinging nettle. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Organic Nettle Leaf by Traditional Medicinals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “All Herbal Ingredients” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Organic Nettle Leaf is a single-ingredient herbal tea made from stinging nettle — the whole plant (above-ground parts and roots). There are no inactive fillers or added ingredients listed for this product.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Stinging Nettle's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports joint health and overall wellness.
  • We looked for evidence on: Osteoarthritis, joint inflammation, arthralgia.
  • The closest evidence on file: Stinging Nettle is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis (Natural Medicines).

The evidence we hold shows stinging nettle is possibly effective for diabetes; research suggests it may help lower blood glucose levels in people with that condition. For allergic rhinitis (hay fever), anemia, asthma, benign prostatic hyperplasia (enlarged prostate), and gingivitis, the evidence isn't robust enough to rate — we simply don't have reliable data yet on whether nettle helps with those.

The evidence, ingredient by ingredient Stinging Nettle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Stinging nettle is generally well tolerated by most adults when used as directed, though constipation or diarrhea can happen. A rare case of liver injury has been reported after prolonged use in a supplement blend, though that product contained other ingredients too.

If you touch raw stinging nettle leaves, you may get itching, rash, and stinging — even sucking on a fresh leaf caused severe tongue swelling in one report. The safety data advises against use during pregnancy, and there isn't enough information about safety while breastfeeding, so talk with your doctor or pharmacist before taking it if you're pregnant or nursing.

Side effects, ingredient by ingredient Stinging Nettle

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stinging Nettle.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 164 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood thinners like warfarin, antidiabetes drugs, diuretic medications (water pills), or lithium. All of these have moderate interactions with stinging nettle that could alter how well your medications work or how much they stay in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Stinging nettle tea may be worth considering if you have diabetes and want to explore herbal support alongside your regular care — but it's not a replacement. If you take blood thinners, diabetes medications, water pills, or lithium, check with your doctor or pharmacist before starting, because nettle can affect how these drugs work.

Talk it over with your own healthcare provider to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Nettle Leaf, straight from the product label.

Brand Traditional Medicinals
Net contents 16 Wrapped Tea Bag(s); 1.13 Ounce(s); 32 Gram(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 306989
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Nettle Leaf by Traditional Medicinals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tea Bag(s)
Maximum serving Sizes:
1 Tea Bag(s)
Servings per container
16
IngredientAmount% DV
Calories0 Calorie(s)--
All Herbal Ingredients0 NP--
Stinging nettle2000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Use this number on all correspondence related to this product JUL2025B0012875 Herbs that work From field to cup, we make sure our teas deliver the benefits of these amazing plants. To deliver consistent high quality teas, we source organically farmed or organically wild-collected herbs from ethical trading partnerships, seeking out medicinal-grade plants. Only a small fraction of the world's herb supply meets our high quality standards. Learn more about our farming communities and our work to create positive social impact at traditionalmedicinals.com

Formulation

Daily herbal Supports joint health & overall wellness

Caffeine free

USDA Organic Certified organic by CCOF. All ingredients certified organic.

Non GMO Project Verified nongmoproject.org

Herbal power Supports joint health and overall wellness. Taste Earthy, fresh and grassy.

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic

Non GMO Project Verified nongmoproject.org OK (Kosher) Certified B Corporations

Formula

OK (Kosher)

Plant story In herbalism, nettle is the mother of all spring tonics. Known for its ability to support the whole body as well as joint health, this tea can help kick-start your body when you're feeling stagnant. Some of our favorite nettle hails from the wild meadows of Eastern Europe, where collectors harvest it by hand.

Precautions

Consult your healthcare practitioner prior to use if you are diabetic or if you are pregnant or breastfeeding.

In sensitive individuals, nettle leaf preparations may occasionally cause mild gastrointestinal upset.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

To enjoy Pour 8 oz. freshly boiled water over 1 tea bag. Cover & steep for 10-15 min. Squeeze & remove tea bag to ensure maximum goodness. Enjoy 3-4 cups per day.

See for yourself

Organic Nettle Leaf by Traditional Medicinals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Organic Nettle Leaf by Traditional Medicinals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tea Bag(s) Dosage formOther (e.g. Tea Bag) Servings per container16 Amounts shown are per serving.

All Herbal Ingredients

0 NP per serving
Interaction report

Organic Nettle Leaf by Traditional Medicinals Drug Interactions

Want to check YOUR meds against Organic Nettle Leaf?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
164Drugs
164 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Nettle Leaf with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stinging nettle4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Organic Nettle Leaf, from the product label.

Traditional Medicinals

See all Traditional Medicinals products
Name
Traditional Medicinals
Street Address
4515 Ross Road
City
Sebastopol
State
CA
ZipCode
95472
Web Address
traditionalmedicinals.com
Pharmacist Counseling Corner

Organic Nettle Leaf by Traditional Medicinals: Common Questions

Does Organic Nettle Leaf by Traditional Medicinals interact with any medications?
Yes. Based on its ingredients, Organic Nettle Leaf has a known interaction with 164 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Nettle Leaf contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does stinging nettle actually help with diabetes?
Research suggests it's possibly effective — clinical studies show stinging nettle might lower blood glucose levels in people with diabetes. That said, it's not proven as a standalone treatment, and you'd still need your regular diabetes medications.
Can I drink this if I'm pregnant or breastfeeding?
No — the safety data advises against it during pregnancy due to traditional concerns about effects on the uterus. If you're breastfeeding, there isn't enough safety information, so talk with your doctor or pharmacist before using it.
What are the most common side effects?
Taken by mouth, stinging nettle is generally well tolerated, but some people experience constipation or diarrhea. If you handle raw nettle leaves, you may get itching, rash, and stinging skin — that's just from touching the plant itself.
Is this product just nettle, or are there fillers?
It's just stinging nettle in tea-bag form — no inactive ingredients or fillers are listed.
I'm on a water pill for blood pressure. Can I use this?
Stinging nettle has its own diuretic effect, so combining it with a water pill could intensify that. Check with your doctor or pharmacist first — they may need to adjust your dose or monitor you more closely.
I take warfarin for my heart. Is this safe?
Stinging nettle is high in vitamin K, which can reduce how well warfarin works when you take large amounts of nettle. Talk with your doctor before starting — they may want to check your blood-clotting levels more often.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Nettle Leaf is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Nettle Leaf label
Sources

Sources & How We Checked

Organic Nettle Leaf's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
  10. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
  11. Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
  12. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
  13. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
  14. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
  15. Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
  16. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
  17. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
  18. Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
  19. Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
  20. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
  21. Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
  22. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
  23. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed

See these in context on the Stinging Nettle monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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