Organic Peppermint Tea Bags Ingredients & Drug Interactions
by FGO
What is this page for?
First and foremost: checking Organic Peppermint Tea Bags against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Peppermint Tea Bags is a dietary supplement by FGO with 2 active ingredients. Its ingredients are commonly taken for mental alertness and reducing fatigue, improving athletic performance, headache and migraine relief.Based on those ingredients, 1,167 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Peppermint, Caffeine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Peppermint Tea Bags by FGO
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Peppermint Tea Bags by FGO — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Peppermint Tea Bags by FGO
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This tea contains 2 active ingredients: caffeine and peppermint. Caffeine is the stimulant compound found naturally in tea leaves; peppermint (the herb) provides the flavor and aroma.
There are no inactive filler ingredients listed for this product.
Does it work?
Strong evidence
Caffeine is effective for neonatal apnea (a breathing problem in newborns) and postoperative headache (headache after surgery). It's likely effective for boosting mental alertness and athletic performance.
There's possibly effective evidence for bronchopulmonary dysplasia (a chronic lung condition in premature infants). Peppermint tea is likely effective for irritable bowel syndrome (IBS).
It's possibly effective for dyspepsia (indigestion), chemotherapy-induced nausea and vomiting, barium enema-related colonic spasm, and endoscopy-related side effects. The evidence we hold doesn't establish use beyond these areas.
How safe is it?
Well-documented data
Caffeine in moderate amounts is generally well tolerated in healthy adults, but high doses can cause serious side effects. The most common side effects are anxiety, dependence with long-term use, diarrhea, increased urination, stomach irritation, headache, insomnia, tremors, nausea, and restlessness.
Rarely, stroke has been reported. Caffeine can also cause anaphylaxis (a severe allergic reaction) in sensitive people, though true caffeine allergy is uncommon.
High caffeine intake during pregnancy is linked to risks; ask your doctor about safe limits. Small amounts pass into breast milk, and moderate intake is usually considered acceptable, but caffeine can affect the baby.
Peppermint tea and culinary amounts are generally safe. The most common side effects from peppermint are abdominal pain, anal burning, belching, diarrhea, dry mouth, heartburn, nausea, and vomiting.
A rare case of severe allergic reaction (anaphylaxis) has been reported with peppermint candy. Peppermint is likely safe in pregnancy and lactation.
Concentrated peppermint oil should be used only with your doctor's approval, as it can cause chemical burns when used improperly.
Meds to double-check
Major interaction found
Before you take this tea, check whether you're on ephedrine or related stimulants (Major interaction with caffeine). Then verify any sedatives or seizure medications like pentobarbital, phenobarbital, or carbamazepine; blood vessel relaxers like dipyridamole; antipsychotics like clozapine; acid reflux drugs like cimetidine; quinolone antibiotics; blood pressure or cholesterol drugs; or cyclosporine (an immune-suppressing medication).
Use the search tool to look up your exact medications.
The bottom line
Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Peppermint tea with caffeine works well for IBS and can boost mental alertness and athletic performance. If you take any prescription medication—especially stimulants, sedatives, seizure drugs, blood pressure or cholesterol drugs, or immunosuppressants—check your exact medications with our tool before you start.
Talk to your pharmacist or doctor if you're pregnant, breastfeeding, or have a caffeine sensitivity.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Peppermint Tea Bags, straight from the product label.
| Brand | FGO |
|---|---|
| Barcode (UPC) | X0027BQGNV |
| Net contents | 20 Herbal Tea Bag(s); 35 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 321165 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Peppermint Tea Bags by FGO, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Caffeine | 0 mg | -- |
| Peppermint | 1750 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
USDA Organic Non GMO Project Verified nongmoproject.org
CCOF Certified Organic Organic is non-GMO & more
Formulation
USDA Organic
Non GMO Project Verified nongmoproject.org
Eco-Conscious From USA
FGO products are sourced from nutrient dense origins around the world. We are committed to delivering the highest quality, certified organic products at a fair price, to help you live healthy and feel good. Raw from the United States.
Premium Tea Bag: Abacá Hemp Fiber Paper Eco-Conscious: No unnecessary waste from wrapping, strings or staples. Just organic tea in premium bags.
Free of dyes, adhesive, glue and chlorine bleach. Non-GMO. Naturally Caffeine Free: This herbal tea is caffeine free.
CCOF Certified Organic Organic is non-GMO & more Certified Organic By: CCOF
CCOF Certified Organic Organic is non-GMO & more
General Statements
Healthy feels good
For recipes, giveaways and more visit us at www.FGOrganics.com
Try our black or green teas if you're looking for a boost!
Suggested/Recommended/Usage/Directions
Drop a bag into your favorite cup Add 8oz Fresh Boiling Water Steep tea for 5-7 minutes Smile, sip and feel good
Formula
Remain calm, cool and collected with a refreshing sip of our organic Peppermint Tea. Praised for its pleasant, minty flavor, peppermint tea is the perfect addition to a cozy afternoon on a sun-dappled couch. One whiff of this aromatic tea is enough to help relax the mind and enliven the senses. This bag contains 20 tea bags filled with certified organic, 100% raw peppermint tea from the USA.
Fine Organic Tea: Certified Organic Peppermint from USA (Mentha piperita).
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Consult with a healthcare provider prior to use if you are currently pregnant, nursing, taking medication, or if you have a medical condition.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Peppermint Tea Bags by FGO label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Peppermint Tea Bags by FGO
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Cup Brewed Tea(s) Dosage formOther (e.g. Tea Bag) Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Caffeine
Interacts with655 drugs
Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredn...
Caffeine monograph & interactionsPeppermint
Interacts with796 drugs
Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated f...
Peppermint monograph & interactionsOrganic Peppermint Tea Bags by FGO Drug Interactions
HelloPharmacist Interaction Report
FGO Organic Peppermint Tea Bags contains two active ingredients — caffeine and peppermint — that together interact with a large number of medications.
The most serious concern is caffeine's interaction with ephedrine (a stimulant), which carries Major severity and can increase the risk of serious, life-threatening effects like high blood pressure and heart attack.
Read the full breakdown — every affected drug type, severity by severity
Caffeine also has Moderate interactions with several drug types: pentobarbital and phenobarbital (sedatives and seizure medications, which caffeine may weaken), dipyridamole (a blood vessel relaxer used before stress tests, which caffeine can interfere with), clozapine (an antipsychotic, which caffeine can make build up to toxic levels), cimetidine (an acid reflux medication that can raise caffeine levels in your body), quinolone antibiotics (which can raise caffeine levels), and carbamazepine (a seizure medication that caffeine may reduce).
Peppermint carries Moderate interactions with several enzyme substrates — CYP2C19 substrates, CYP2C9 substrates, and CYP3A4 substrates (a broad group that includes many blood pressure, cholesterol, and immunosuppressant drugs) — because it can slow how your body clears them. Peppermint also has a Moderate interaction with cyclosporine (an immune-suppressing drug used after transplants).
It has a Minor interaction with CYP1A2 substrates, though clinical evidence suggests peppermint tea may not significantly affect these in practice.
Altogether, these interactions span 1,156 individual medications. Use the medication checker on this page to look up your exact prescriptions before you start this tea.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Organic Peppermint Tea Bags?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Peppermint Tea Bags interact with 1,167 drugs. Click any drug to see the details.
2 of the 2 ingredients in Organic Peppermint Tea Bags interact with drugs. Each result below shows which ingredient is responsible. Peppermint Caffeine
Aminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
CaffeineStimulant Drugs, Ephedrine Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Aminophylline, Amobarbital, Ephedrine interactionCarbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine TannateQuadratuss, Ry Tuss, Rynatuss, Tri Tannate Plus
How Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineEphedrine, Stimulant Drugs Major
Interaction Summary
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Read the full Caffeine + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionPeppermintCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionDyphylline, Ephedrine, Guaifenesin, PhenobarbitalLufyllin-EPG
How Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
CaffeineStimulant Drugs, Phenobarbital (luminal) +1 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interactionEphedrine, Guaifenesin (otc Drug)Ephedrine Formula 400, Ephedrine Plus Tabs
How Ephedrine, Guaifenesin (otc Drug) interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
CaffeineStimulant Drugs, Ephedrine Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Ephedrine, Guaifenesin (otc Drug) interactionEphedrine, Guaifenesin, Phenobarbital, TheophyllineMudrane GG
How Ephedrine, Guaifenesin, Phenobarbital, Theophylline interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineTheophylline, Phenobarbital (luminal) +2 Major
Interaction Summary
Theoretically, caffeine might increase the levels and adverse effects of theophylline.
Read the full Caffeine + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionEphedrine, Hydroxyzine, TheophyllineAmi Rax, Marax
How Ephedrine, Hydroxyzine, Theophylline interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineStimulant Drugs, Theophylline +1 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Ephedrine, Hydroxyzine, Theophylline interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Ephedrine, Hydroxyzine, Theophylline interactionEphedrine, Phenobarbital, Potassium Iodide, TheophyllineMudrane, Quadrinal
How Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
CaffeineStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interactionEphedrine, Phenobarbital, TheophyllineTedral
How Ephedrine, Phenobarbital, Theophylline interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
CaffeineStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Ephedrine, Phenobarbital, Theophylline interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
CaffeineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Caffeine + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Abiraterone interactionCaffeineCytochrome P450 1a2 (cyp1a2) Inhibitors Minor
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Read the full Caffeine + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Caffeine + Abrocitinib interactionPeppermintCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP2C19 substrates.
Read the full Peppermint + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
CaffeineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Caffeine + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Caffeine + Acetaminophen, Aspirin interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineAnticoagulant/antiplatelet Drugs, Stimulant Drugs Moderate
Interaction Summary
Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Caffeine + Acetaminophen, Aspirin, Caffeine interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineStimulant Drugs, Phenylpropanolamine Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
PeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Butalbital, Caffeine interactionCaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
PeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Butalbital, Caffeine, Codeine interactionCaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
PeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Caffeine, Codeine interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Acetaminophen, Caffeine, Dihydrocodeine interactionCaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
CaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Caffeine, Isometheptene interactionPeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Acetaminophen, Caffeine, Pyrilamine interactionCaffeineDiuretic Drugs, Stimulant Drugs Moderate
Interaction Summary
Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.
Read the full Caffeine + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
PeppermintCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Organic Peppermint Tea Bags — through 2 ingredients. Tap an ingredient for the detail:
PeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCaffeineStimulant Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Organic Peppermint Tea Bags — through 1 ingredient. Tap an ingredient for the detail:
PeppermintCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Peppermint Tea Bags with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Peppermint
Cyclosporine (Neoral, Sandimmune)
Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.
Caffeine
Ephedrine
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Use of ephedrine with caffeine can increase the risk of stimulatory adverse effects. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.
Adenosine (Adenocard)
Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Some evidence shows that caffeine is a competitive inhibitor of adenosine and can reduce the vasodilatory effects of adenosine in humans. However, other research shows that caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Anticoagulant/Antiplatelet Drugs
Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Caffeine is reported to have antiplatelet activity. Theoretically, it might increase the risk of bleeding when used concomitantly with these agents; however, this interaction has not been reported in humans.
Beta-Adrenergic Agonists
Theoretically, large amounts of caffeine might increase the cardiac inotropic effects of beta-agonists.
Carbamazepine (Tegretol)
Theoretically, caffeine might reduce the effects of carbamazepine and increase the risk for convulsions.
Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.
Cimetidine (Tagamet)
Theoretically, cimetidine might increase the levels and adverse effects of caffeine.
Cimetidine decreases the rate of caffeine clearance by 31% to 42%.
Clozapine (Clozaril)
Caffeine might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Caffeine might increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg per day inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Although researchers speculate that caffeine might inhibit CYP1A2, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients more sensitive to an interaction between clozapine and caffeine. In one case report, severe, life-threatening clozapine toxicity and multiorgan system failure occurred in a patient with schizophrenia stabilized on clozapine who consumed caffeine 600 mg daily.
Dipyridamole (Persantine)
Theoretically, caffeine might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Caffeine inhibits dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Disulfiram (Antabuse)
Theoretically, disulfiram use might increase the levels and adverse effects of caffeine.
Disulfiram decreases the rate of caffeine clearance.
Diuretic Drugs
Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.
Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.
Estrogens
Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Estrogen inhibits caffeine metabolism.
Ethosuximide (Zarontin)
Theoretically, caffeine might reduce the effects of ethosuximide and increase the risk for convulsions.
Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.
Felbamate (Felbatol)
Theoretically, caffeine might reduce the effects of felbamate and increase the risk for convulsions.
Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.
Flutamide (Eulexin)
Theoretically, caffeine might increase the levels and adverse effects of flutamide.
In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. However, this effect has not been reported in humans.
Fluvoxamine (Luvox)
Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Fluvoxamine reduces caffeine metabolism.
Lithium
Abrupt caffeine withdrawal might increase the levels and adverse effects of lithium.
Caffeine has diuretic activity. When abruptly discontinued, caffeine may alter the clearance of lithium. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal and 6 case reports of elevated serum lithium levels after reducing or eliminating caffeine intake. In one case, a male with schizoaffective disorder stabilized on lithium had an elevated lithium level after reducing his caffeine intake by 87%. At a later date, he increased his caffeine intake by 6-fold, resulting in a subtherapeutic lithium level and a recurrence of psychiatric symptoms.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Caffeine has been shown to inhibit monoamine oxidase (MAO) A and B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.
Nicotine
Theoretically, concomitant use might increase the risk of hypertension.
Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.
Pentobarbital (Nembutal)
Theoretically, caffeine might decrease the effects of pentobarbital.
Caffeine might negate the hypnotic effects of pentobarbital.
Phenobarbital (Luminal)
Theoretically, caffeine might reduce the effects of phenobarbital and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenobarbital. However, the exact mechanism of this interaction is unclear.
Phenylpropanolamine
Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.
Phenytoin (Dilantin)
Theoretically, caffeine might reduce the effects of phenytoin and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.
Pioglitazone (Actos)
Theoretically, caffeine might increase the levels and clinical effects of pioglitazone.
Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.
Quinolone Antibiotics
Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Quinolones (also called fluoroquinolones) can decrease caffeine clearance by inhibiting cytochrome P450 1A2 (CYP1A2) enzyme.
Riluzole (Rilutek)
Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce the metabolism of one or both agents.
Brand information
Manufacturer and brand details for Organic Peppermint Tea Bags, from the product label.
FGO
See all FGO products- Name
- FGO
- City
- Seattle
- State
- WA
- ZipCode
- 98117
- Web Address
- www.FGOrganics.com
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The Full Monographs Behind Organic Peppermint Tea Bags’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Caffeine
Interacts with 655 drugsCaffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredness for most healthy adults, but too muc...
Read the full Caffeine monograph → Herb & supplement monographPeppermint
Interacts with 796 drugsPeppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...
Read the full Peppermint monograph →Sources & How We Checked
Organic Peppermint Tea Bags's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 277 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Caffeine 236 references
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