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Dietary supplement

Organic Skullcap Ingredients & Drug Interactions

by Ra Herbals

Organic Skullcap label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Skullcap against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Skullcap is a dietary supplement by Ra Herbals with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, trouble sleeping, nervous tension.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Skullcap. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Skullcap by Ra Herbals

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Skullcap by Ra Herbals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Skullcap by Ra Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

Ra Herbals Organic Skullcap is a liquid extract containing one active ingredient: skullcap, a botanical traditionally used for various conditions. The product also contains cane alcohol and distilled water as inactive ingredients that make up the liquid base.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Skullcap product and its label doesn't state a use — see Skullcap's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold on skullcap's effectiveness is limited. It's been studied for epilepsy, stress, stroke, spasticity, contact dermatitis, and premenstrual dysphoric disorder (PMDD), but in each case there isn't enough reliable evidence to rate how well it works.

If you're considering this product for a specific health reason, talking it over with your doctor or pharmacist can help you weigh what the research does and doesn't show.

The evidence, ingredient by ingredient Skullcap

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Skullcap is generally well tolerated, though the safety data is sparse. The most common side effects reported when taken by mouth are cognitive impairment, digestive disturbances, and sedation — though these occurred at higher doses (350 mg three times daily) in clinical study.

A single 100 mg dose didn't show adverse brain effects in testing, but 200 mg doses might cause sedation and thinking problems. Around 9% of people in one trial on the higher dose had mild digestive issues.

The safety data advises against using this product during pregnancy or while breastfeeding — there isn't enough information to know it's safe in these situations. If you're pregnant, planning to become pregnant, or nursing, check with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Skullcap

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Skullcap.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Ra Herbals Organic Skullcap, check with your doctor or pharmacist if you take any CNS depressants — drugs that slow brain activity, such as sedatives, sleep aids (including over-the-counter ones), anxiety medications, or certain pain relievers. Skullcap may add to their effects, raising your risk of sedation or cognitive impairment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Skullcap is often used short-term, but the evidence for what it actually does is limited, and product quality can vary — use it with care. The main thing to watch for is combining it with sedatives, sleep aids, anxiety medications, or other CNS depressants, which could increase drowsiness or affect your thinking.

Talk with your doctor or pharmacist about whether this product makes sense for you and whether it's safe alongside anything else you're taking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Skullcap, straight from the product label.

Brand Ra Herbals
Barcode (UPC) 767787973438
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 305508
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Skullcap by Ra Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
767787973438
IngredientAmount% DV
Skullcap0 NP--

Other ingredients: Cane Alcohol, Water, Distilled

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bioregional Herbal Company

Instagram Facebook Twitter @sungodmeds

Seals/Symbols

OTCO (Oregon Tilth Certified Organic)

USDA Organic

Formulation

Certified Organic by: Oregon Tilth

Oregon Made

Non-GMO Gluten Free

S (Sleep Aid) M (Mental Ease) P (Pain Relief)

Precautions

Do not exceed. Caution: Do not use if safety seal is missing or broken.

If pregnant, nursing, or on medication, consult with your health care practitioner before use.

Keep out of reach of children.

Brand IP Statement(s)

Ra Herbals Herbs enlightened

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Shake Well Before Use

See website for recommended dosage.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Skullcap by Ra Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Skullcap label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Skullcap by Ra Herbals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Skullcap

Interacts with
248 drugs
0 NP per serving Form: Scutellaria lateriflora

American skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally cons...

Skullcap monograph & interactions

Other (inactive) ingredients: Cane Alcohol, Water, Distilled. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Skullcap by Ra Herbals Drug Interactions

Want to check YOUR meds against Organic Skullcap?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

Skullcap 248

Individual Drug Interactions

The ingredients in Organic Skullcap interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Skullcap interact with drugs. Each result below shows which ingredient is responsible. Skullcap

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Skullcap with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Skullcap1 drug type · 248 drugs

Cns Depressants

Theoretically, skullcap can have additive effects when used with other CNS depressants.
Animal and clinical research suggests that skullcap can cause sedation and cognitive impairment.

Likelihood Possible Evidence D
Skullcap full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Skullcap, from the product label.

Ra Herbals

See all Ra Herbals products
Name
Sun God Medicinals
Street Address
540 E Vilas Rd Ste C
City
Central Point
State
OR
ZipCode
97502
Phone Number
888-470-7394
Web Address
www.sungodmedicinals.com
Pharmacist Counseling Corner

Organic Skullcap by Ra Herbals: Common Questions

Does Organic Skullcap by Ra Herbals interact with any medications?
Yes. Based on its ingredients, Organic Skullcap has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Skullcap contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take skullcap if I'm pregnant or breastfeeding?
The safety data advises against it during pregnancy, and skullcap should be avoided while breastfeeding because there isn't enough information to know it's safe. Talk with your doctor or pharmacist about your specific situation before taking it.
What are the most common side effects?
The most common side effects reported with skullcap are sedation, cognitive impairment (trouble thinking clearly), and digestive disturbances. A small number of people at higher doses experienced vivid dreams. Mild digestive issues were reported in around 9% of people in one trial.
Is it safe to take skullcap long-term?
Skullcap is often used short-term, but the evidence on long-term safety is limited and product quality can vary. The facts advise using it with care and suggest that not enough safety data exists for extended use. Talk with your doctor or pharmacist about your timeline and needs.
Does skullcap actually work for stress or other conditions?
The evidence we have isn't strong enough to rate how well skullcap works for stress, epilepsy, stroke, spasticity, contact dermatitis, or premenstrual dysphoric disorder. There isn't enough reliable research to say whether it's effective for any of these.
What's in this product besides skullcap?
This liquid extract contains cane alcohol and distilled water as inactive ingredients. There are no other active ingredients — skullcap is the only active one.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Skullcap is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Skullcap label
Go deeper

The Full Monographs Behind Organic Skullcap’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Skullcap

Interacts with 248 drugs

American skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally considered relatively safe for short-term us...

Read the full Skullcap monograph →
Sources

Sources & How We Checked

Organic Skullcap's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Skullcap 3 references
  1. Wolfson P, Hoffmann DL. An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers. Altern Ther Health Med 2003;9:74-8.
  2. Awad, R., Arnason, J. T., Trudeau, V., Bergeron, C., Budzinski, J. W., Foster, B. C., and Merali, Z. Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Phytomedicine. 2003;10(8):6 PubMed
  3. Brock C, Whitehouse J, Tewfik I, Towell T. American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers. Phytother Res 2014;28(5):692-8.

See these in context on the Skullcap monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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