No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

PEA Luteolin Select Ingredients & Drug Interactions

by Moss Nutrition

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

PEA Luteolin Select is a dietary supplement by Moss Nutrition with 2 active ingredients. Its ingredients are commonly taken for chronic pain, nerve (neuropathic) pain, inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of PEA Luteolin Select by Moss Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

PEA Luteolin Select contains 2 active ingredients. Levagen+ is palmitoylethanolamide (often called PEA), a natural compound your body makes that may help ease joint pain and support nerve function.

Luteolin is a plant compound, though we don't have detailed ingredient information on file for it. The capsule also contains a few inactive ingredients — hypromellose (a capsule material), stearate, and silicon dioxide — that help hold everything together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Endocannabinoid receptor support.
  • We looked for evidence on: Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Complex regional pain syndrome, Fibromyalgia, Migraine headache, Multiple sclerosis (MS), Neuropathic pain — and 4 related terms.
  • The strongest evidence on file: Palmitoylethanolamide (pea) is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Palmitoylethanolamide (pea) is rated "Insufficient Reliable Evidence To Rate" for Migraine headache, Fibromyalgia, Multiple sclerosis (MS), Neuropathic pain, and more.

Palmitoylethanolamide shows possibly effective evidence for osteoarthritis, meaning some studies support its use for joint pain. For migraine headache, carpal tunnel syndrome, autism spectrum disorder, and cannabis use disorder, the evidence isn't strong enough to say whether it works — that's insufficient reliable evidence.

For spinal cord injury, the available evidence suggests it's possibly ineffective. We don't have effectiveness data on file for luteolin.

The evidence, ingredient by ingredient Palmitoylethanolamide (pea)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Palmitoylethanolamide is generally well tolerated in studies, though long-term safety data are limited. The most common side effect when taken by mouth is nausea, reported rarely and as mild and temporary.

A small number of people applying PEA lotion to skin experienced mild stinging, scaling, or redness, but these didn't happen more often than with the lotion base alone. There isn't enough safety information to recommend this product during pregnancy or while breastfeeding — talk with your doctor or pharmacist about whether it's right for you in those situations.

Side effects, ingredient by ingredient Palmitoylethanolamide (pea)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for palmitoylethanolamide. However, we couldn't check luteolin.

Run your medications through the checker on this page before you start, and mention luteolin to your pharmacist if it flags anything.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're dealing with osteoarthritis, palmitoylethanolamide may be worth a try based on the evidence we have. If you're pregnant, breastfeeding, or taking any medications, check with your pharmacist first — especially since we couldn't verify luteolin's safety profile.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PEA Luteolin Select, straight from the product label.

Brand Moss Nutrition
Barcode (UPC) M173
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334946
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PEA Luteolin Select by Moss Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
M173
IngredientAmount% DV
Luteolin50 mg--
Levagen+300 mg--

Other ingredients: Hypromellose, Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 1 capsule two times per day or as directed by your healthcare professional.

Precautions

Warning: If you are taking medication, have a medical condition or an upcoming medical procedure, or are pregnant or nursing consult a physician before using.

If adverse reactions occur, discontinue use & consult your healthcare practitioner.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Moss Nutrition Professional Supplements Est. 1991

Levagen + is a registered trademark of Gencor.

Formula

Levagen+

Formulation

Endocannabinoid receptor support

Does not contain gluten.

FDA Statement of Identity

Dietary Supplement

Storage

Store sealed in a cool, dry place.

See for yourself

PEA Luteolin Select by Moss Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PEA Luteolin Select by Moss Nutrition

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Luteolin

50 mg per serving

Levagen+

No known
interactions
300 mg per serving Form: Palmitoylethanolamide

Palmitoylethanolamide (PEA) is a fat-like molecule made naturally in the body and studied mainly for pain and inflammation. Some research suggests it...

Levagen+ monograph & interactions

Other (inactive) ingredients: Hypromellose, Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

PEA Luteolin Select by Moss Nutrition Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in PEA Luteolin Select. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for PEA Luteolin Select, from the product label.

Moss Nutrition

See all Moss Nutrition products
Name
Moss Nutrition Products
Street Address
380 Russell Street
City
Hadley
State
MA
ZipCode
01035
Phone Number
800-851-5444
Web Address
www.mossnutrition.com
Pharmacist Counseling Corner

PEA Luteolin Select by Moss Nutrition: Common Questions

Does PEA Luteolin Select by Moss Nutrition interact with any medications?
We do not currently list a known interaction for the mapped ingredients in PEA Luteolin Select. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
PEA Luteolin Select contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Levagen+?
Levagen+ is palmitoylethanolamide (PEA), a compound your body naturally produces. It's been studied mainly for joint pain in osteoarthritis, where some evidence supports its use.
Will this help my migraines?
The evidence for palmitoylethanolamide in migraine isn't solid enough yet to say whether it works. If you're interested, talk with your doctor about whether to try it alongside your current plan.
Can I take this while I'm pregnant?
There isn't enough safety data to know, so the safety information advises against it during pregnancy. Talk with your doctor or pharmacist about your specific situation.
What's the most common side effect?
Nausea is reported rarely and is mild and temporary when it occurs. Overall, palmitoylethanolamide is well tolerated in studies.
Why can't you check luteolin for drug interactions?
We don't hold interaction data for luteolin in our database. That's why it's important to run your medications through the checker on this page and mention luteolin to your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PEA Luteolin Select is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PEA Luteolin Select label
Sources

Sources & How We Checked

PEA Luteolin Select's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Palmitoylethanolamide (pea) 4 references
  1. Indraccolo U, Barbieri F. Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. Eur J Obstet Gynecol Reprod Biol. 2010 May;150(1):76-9. PubMed
  2. Murina F, Graziottin A, Felice R, Radici G, Tognocchi C. Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation. J Low Genit Tract Dis. 2013 Apr;17(2):111-6.
  3. Papetti L, Sforza G, Tullo G, et al. Tolerability of palmitoylethanolamide in a pediatric population suffering from migraine: A pilot study. Pain Res Manag 2020;2020:3938640. PubMed
  4. Visse K, Blome C, Phan NQ, Augustin M, Ständer S. Efficacy of body lotion containing N-palmitoylethanolamine in subjects with chronic pruritus due to dry skin: A dermatocosmetic study. Acta Derm Venereol. 2017;97(5):639-641. PubMed

See these in context on the Palmitoylethanolamide (pea) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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