Interactions on record — worth a quick check against your medications. Based on 2 of 6 ingredients. Check your meds →
Dietary supplement

Performance Probiotic Natural Acai Flavor Ingredients & Drug Interactions

by AIVIA

Performance Probiotic Natural Acai Flavor label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Performance Probiotic Natural Acai Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Performance Probiotic Natural Acai Flavor is a dietary supplement by AIVIA with 6 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,083 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Bacillus subtilis DE-111. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Performance Probiotic Natural Acai Flavor by AIVIA

Ask about any prescription or over-the-counter medication and we check it for interactions with Performance Probiotic Natural Acai Flavor by AIVIA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Performance Probiotic Natural Acai Flavor by AIVIA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 6 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This powder contains 5 active ingredients: Serratiopeptidase, ProHydrolase, a proprietary probiotic blend, Bifidobacterium animalis lactis, Lactobacillus rhamnosus, and Bacillus subtilis DE-111. Bacillus subtilis is a beneficial bacteria strain; the Bifidobacterium and Lactobacillus species are common probiotic organisms meant to support your gut.

Serratiopeptidase is an enzyme, and ProHydrolase is a proprietary enzyme formula. The product also contains several inactive ingredients — fructooligosaccharides, sunflower oil creamer, acai flavoring, inulin, citric acid, silicon dioxide, and stevia — that serve as sweeteners, binders, or texture modifiers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: optimize results and enhance active lifestyle.
  • We looked for evidence on: Athletic performance, Sports performance, Exercise recovery, Endurance.
  • The closest evidence on file: Bacillus Subtilis is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

Bacillus subtilis is possibly effective for antibiotic-associated diarrhea — loose stools that happen after you've taken antibiotics. For everything else the data cover — athletic performance, cirrhosis, general constipation, eczema, and diabetes — the evidence isn't strong enough to establish how well it works.

We hold no effectiveness data for the other active ingredients in this formula.

The evidence, ingredient by ingredient Black Psyllium Bacillus Subtilis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus subtilis is generally well tolerated in healthy adults, though quality and safety vary by product and strain. The safety data isn't complete, so your doctor should weigh in before you start it, especially if you have any health conditions.

A small number of trial participants reported headache; diarrhea has been reported rarely. There are rare cases of Bacillus subtilis infection (bacteremia and meningitis) from frequent consumption of natto — a fermented soybean product containing a related strain — in people who were already immunocompromised due to age, diabetes, kidney failure, or other serious conditions.

Pregnancy and lactation safety data for this ingredient are not on file — talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Black Psyllium Bacillus Subtilis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Black Psyllium, Bacillus Subtilis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,084 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antibiotic medications before starting this product. Taking Bacillus subtilis at the same time as antibiotics may reduce how well the probiotic works — antibiotics can kill the live organisms in the formula.

Space them apart, and ask your pharmacist or doctor for the right timing. We couldn't check four of the active ingredients against drug databases, so running your full medication list through the tool on this page is important.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is built around Bacillus subtilis and other probiotic strains, with the strongest evidence for antibiotic-associated diarrhea. If you take antibiotics, you'll need to space them apart from this powder — check with your doctor or pharmacist on timing.

For other uses, the evidence is limited. Before you start, run your medications through the checker on this page, and talk it over with your doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Performance Probiotic Natural Acai Flavor, straight from the product label.

Brand AIVIA
Net contents 30 Stick Pack(s); 75 Gram(s); 2.65 Ounce(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 313182
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Performance Probiotic Natural Acai Flavor by AIVIA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 Gram(s)
Maximum serving Sizes:
2.5 Gram(s)
Servings per container
30
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates2 Gram(s)1%
Serratiopeptidase0 NP--
Dietary Fiber1 Gram(s)4%
ProHydrolase0 NP--
Proprietary Probiotic Blend0 NP--
Bifidobacterium animalis lactis0 NP--
Lactobacillus rhamnosus0 NP--
Bacillus subtilis DE-1110 NP--
Proprietary Enzyme Blend0 NP--

Other ingredients: Fructooligosaccharides, Sunflower Oil Creamer, natural Acai Flavor, Inulin, Probiotic Blend, Citric Acid, Silicon Dioxide, Steviol Glycosides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Performance probiotic + Core power enzymes

More than just gut health, AIVIA Probiotic was formulated to boost performance. When combined with proper diet and exercise, the blends of clinically-studied probiotics and enzymes strengthen your core from deep within for better exercise performance, recovery, and body composition.

General Statements

30 Stick Packs (2.5g each/0.09 oz.)

The guts to win

Powered by Nature's Sunshine We are committed to you and our planet. Scan to learn more. Please recycle this carton.

FDA Statement of Identity

Dietary Supplement

Formulation

Non GMO

100% Vegetarian

Optimize your results and enhance your active lifestyle with AIVIA Probiotic.

No added sugars

Benefits Supports exercise recovery Helps optimize body composition Supports strength training results Supports normal fat metabolism Supports healthy joints and muscles

Precautions

Contains milk, soy, wheat

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Directions: Pour contents of one packet directly into mouth.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

AIVIA Active nutrition

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Performance Probiotic Natural Acai Flavor by AIVIA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Performance Probiotic Natural Acai Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Performance Probiotic Natural Acai Flavor by AIVIA

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2.5 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Proprietary Probiotic Blend

0 NP per serving

Proprietary Enzyme Blend

0 NP per serving
  • › Serratiopeptidase
  • › ProHydrolase

Other (inactive) ingredients: Fructooligosaccharides, Sunflower Oil Creamer, Natural Acai Flavor, Inulin, Probiotic Blend, Citric Acid, Silicon Dioxide, Steviol Glycosides. These complete the product’s ingredient list but are not active constituents.

Interaction report

Performance Probiotic Natural Acai Flavor by AIVIA Drug Interactions

Want to check YOUR meds against Performance Probiotic Natural Acai Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,083Drugs
205 Moderate 1,878 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Bacillus subtilis DE-111 182

Individual Drug Interactions

The ingredients in Performance Probiotic Natural Acai Flavor interact with 2,083 drugs. Click any drug to see the details.

2 of the 6 ingredients in Performance Probiotic Natural Acai Flavor interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Bacillus subtilis DE-111

Each ingredient & the kinds of drugs it affects

For each ingredient in Performance Probiotic Natural Acai Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Bacillus subtilis DE-1111 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.

Likelihood Probable Evidence D
Bacillus subtilis DE-111 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Performance Probiotic Natural Acai Flavor, from the product label.

AIVIA

See all AIVIA products
Name
Nature's Sunshine Products, Inc.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
(800) 223-8225
Web Address
naturessunshine.com
Pharmacist Counseling Corner

Performance Probiotic Natural Acai Flavor by AIVIA: Common Questions

Does Performance Probiotic Natural Acai Flavor by AIVIA interact with any medications?
Yes. Based on its ingredients, Performance Probiotic Natural Acai Flavor has a known interaction with 2,083 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Performance Probiotic Natural Acai Flavor contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Bacillus subtilis, and what's it supposed to do?
Bacillus subtilis is a beneficial bacteria strain — a probiotic. It's possibly effective for antibiotic-associated diarrhea, the loose stools some people get after taking antibiotics. For other uses like athletic performance or constipation, the evidence isn't strong enough yet.
Can I take this with my antibiotics?
Not at the same time. Antibiotics can kill the live organisms in this probiotic, which would reduce how well it works. You'll need to space them apart — ask your pharmacist or doctor exactly how many hours to leave between doses.
Are there any side effects I should know about?
Bacillus subtilis is generally well tolerated. A small number of trial participants reported headache, and diarrhea has been reported rarely. If you're immunocompromised — due to age, diabetes, kidney disease, or other serious conditions — talk with your doctor before using this, as there are rare cases of infection in that population.
Is this safe during pregnancy or while breastfeeding?
Safety data for Bacillus subtilis during pregnancy and lactation aren't on file. Talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.
What are the inactive ingredients?
The powder contains fructooligosaccharides, sunflower oil creamer, natural acai flavor, inulin, citric acid, silicon dioxide, and stevia. These are fillers, sweeteners, and flavor ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Performance Probiotic Natural Acai Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Performance Probiotic Natural Acai Flavor label
Go deeper

The Full Monographs Behind Performance Probiotic Natural Acai Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Bacillus Subtilis

Interacts with 182 drugs

Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and digestion. Early research is promising for ce...

Read the full Bacillus Subtilis monograph →
Sources

Sources & How We Checked

Performance Probiotic Natural Acai Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Bacillus Subtilis 10 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Lampropoulos PK, Gkentzi D, Tzifas S, Dimitriou G. Neonatal sepsis due to Bacillus subtilis. Cureus 2021;13(9):e17692. PubMed
  3. La Jeon Y, Yang JJ, Kim MJ, et al. Combined Bacillus licheniformis and Bacillus subtilis infection in a patient with oesophageal perforation. J Med Microbiol 2012;61(Pt 12):1766-1769. PubMed
  4. Wallet F, Crunelle V, Roussel-Delvallez M, Fruchart A, Saunier P, Courcol RJ. Bacillus subtilis as a cause of cholangitis in polycystic kidney and liver disease. Am J Gastroenterol 1996;91(7):1477-8.
  5. Velasco E, Martins CA, Tabak D, Bouzas LF. "Bacillus subtilis" infection in a patient submitted to a bone marrow transplantation. Rev Paul Med 1992;110(3):116-7.
  6. Kato A, Yoshifuji A, Komori K, et al. A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma. J Infect Chemother 2022;28(8):1212-1215. PubMed
  7. Freedman KE, Hill JL, Wei Y, et al. Examining the gastrointestinal and immunomodulatory effects of the novel probiotic Bacillus subtilis DE111. Int J Mol Sci 2021;22(5):2453. PubMed
  8. Lefevre M, Racedo SM, Denayrolles M, et al. Safety assessment of Bacillus subtilis CU1 for use as a probiotic in humans. Regul Toxicol Pharmacol 2017;83:54-65. PubMed
  9. Hanifi A, Culpepper T, Mai V, et al. Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults. Benef Microbes 2015;6(1):19-27. PubMed
  10. Tokano M, Tarumoto N, Imai K, et al. A case of bacterial meningitis caused by Bacillus subtilis var. natto. Intern Med. 2022. Epub ahead of print.

See these in context on the Bacillus Subtilis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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