Perilla Oil 1000 mg Ingredients & Drug Interactions
by Source Naturals
What is this page for?
First and foremost: checking Perilla Oil 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Perilla Oil 1000 mg is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for seasonal and food allergies, asthma and airway inflammation, atopic dermatitis (eczema).Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Perilla Oil 1000 mg by Source Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with Perilla Oil 1000 mg by Source Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Perilla Oil 1000 mg by Source Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Perilla Oil 1000 mg supplies three omega fatty acids: omega-3 (as DHA, docosahexaenoic acid), omega-6, and omega-9. These are delivered in a softgel capsule with gelatin, glycerin, and purified water as inactive ingredients.
Does it work?
Not established
The omega-3 component (DHA) in this product is rated possibly effective for preterm labor and hyperlipidemia (high cholesterol and triglycerides). However, it's rated possibly ineffective for cognitive function and ADHD.
Evidence for the other omega fatty acids in this product isn't established in our data.
How safe is it?
Well-documented data
DHA is generally well tolerated at typical supplement doses for most adults. The most common side effects from oral DHA are belching, fishy aftertaste, loose stools, and nausea.
Rare serious concerns include increased bleeding risk at very high doses. DHA is rated likely safe in pregnancy and lactation, though the safety data advises using it only under your doctor's guidance and choosing a purified, low-mercury source.
If you're breastfeeding, DHA does pass into breast milk and is generally considered acceptable, but check with your doctor on the dose and source.
Meds to double-check
Moderate interaction found
Before starting this product, double-check it with your pharmacist if you take blood pressure medications (antihypertensives) — the DHA may add to their effect and lower your blood pressure more. Blood thinners or antiplatelet drugs and diabetes medications also need review, as DHA may increase bleeding risk theoretically and may raise blood sugar in type 2 diabetes.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This omega-3 supplement may help with cholesterol and triglyceride levels or preterm labor prevention — talk to your doctor about whether it's right for you. If you take blood pressure medications, blood thinners, or diabetes drugs, check with your pharmacist first: the DHA in this product interacts with all three.
Otherwise, expect occasional fishy aftertaste or loose stools.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Perilla Oil 1000 mg, straight from the product label.
| Brand | Source Naturals |
|---|---|
| Barcode (UPC) | 021078018643 |
| Net contents | 90 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 275436 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Perilla Oil 1000 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 30 Calorie(s) | -- |
| Total Fat | 3 Gram(s) | 4% |
| Omega-9 | 312 mg | -- |
| Omega-6 | 360 mg | -- |
| Omega-3 | 1.32 Gram(s) | -- |
| Perilla Seed Oil | 3 Gram(s) | -- |
Other ingredients: Gelatin, Glycerin, Water, Purified
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Formula
Source of plant based omega-3 fatty acids Perilla Oil 1,000 mg
Perilla oil, extracted from the plant Perilla frutescens, is a source of alpha-linolenic acid (ALA). ALA is a precursor to the omega-3 fatty acids EPA and DHA. ALA is similar to fish oil in its benefits, but without any unpleasant aftertaste. ALA may support the health of many organs and body systems, including the cardiovascular system, immune system, skin, brain, and joints. Population and animal studies suggest an association between high dietary intake of ALA and breast and colon health.
Suggested/Recommended/Usage/Directions
Suggested Use: 3 softgels twice daily with food.
Precautions
Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product. People taking anticoagulant or antiplatelet-aggregating prescription medications should consult a health care practitioner prior to taking this product.
Not for topical use.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
Formulation
Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, preservatives, or artificial color, flavor or fragrance.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Copyright SOURCE NATURALS, INC.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Perilla Oil 1000 mg by Source Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Perilla Oil 1000 mg by Source Naturals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Perilla Seed Oil
No knowninteractions
Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human ev...
Perilla Seed Oil monograph & interactions- › Omega-9
- › Omega-6
- › Omega-3
Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.
Perilla Oil 1000 mg by Source Naturals Drug Interactions
HelloPharmacist Interaction Report
Perilla Oil 1000 mg from Source Naturals contains omega-3 (specifically DHA), omega-6, and omega-9 fatty acids.
The omega-3 component carries documented interactions with three major drug categories. DHA may increase the risk of low blood pressure (hypotension) when combined with blood pressure medications (antihypertensives), so if you're on those, your doctor or pharmacist should weigh the benefit against that risk.
Read the full breakdown — every affected drug type, severity by severity
DHA also has moderate interactions with blood thinners and antiplatelet drugs — theoretically it may increase bleeding risk, though most evidence suggests DHA alone doesn't significantly affect clotting. The third concern is with diabetes medications: DHA appears to raise fasting blood sugar in people with type 2 diabetes, which could reduce how well those drugs work.
We couldn't check omega-6 and omega-9 for interactions — we hold no data for those ingredients. Altogether, these interactions span 372 individual medications.
Please run your exact medications through the interaction checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Perilla Oil 1000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Perilla Oil 1000 mg interact with 375 drugs. Click any drug to see the details.
0 of the 1 ingredient in Perilla Oil 1000 mg interact with drugs. Each result below shows which ingredient is responsible.
AbciximabReoPro
How Abciximab interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Perilla Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Omega-3Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 + Anacaulase-bcdb interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Perilla Oil 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Brand information
Manufacturer and brand details for Perilla Oil 1000 mg, from the product label.
Source Naturals
- Name
- Source Naturals, Inc.
- Street Address
- P. O. Box 2118
- City
- Santa Cruz
- State
- CA
- ZipCode
- 95062
- Web Address
- www.sourcenaturals.com
Perilla Oil 1000 mg by Source Naturals: Common Questions
Does Perilla Oil 1000 mg by Source Naturals interact with any medications?
How can one product interact with so many drugs?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Perilla Oil 1000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Perilla Oil 1000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Perilla
Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human evidence is limited or preliminary, so it...
Read the full Perilla monograph → Herb & supplement monographDocosahexaenoic Acid (dha)
Interacts with 375 drugsDHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...
Read the full Docosahexaenoic Acid (dha) monograph →Sources & How We Checked
Perilla Oil 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 53 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Docosahexaenoic Acid (dha) 49 references
- Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
- Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
- Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
- Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
- Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
- Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
- FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
- Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
- Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
- Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
- Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
- Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
- Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
- Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
- Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
- Malcolm CA, McCulloch DL, Montgomery C, et al. Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: a double blind, prospective, randomised trial. Arch Dis Child Fetal Neonatal Ed 2003;88: DOI
- Sanjurjo P, Ruiz-Sanz JI, Jimeno P, et al. Supplementation with docosahexaenoic acid in the last trimester of pregnancy: maternal-fetal biochemical findings. J Perinat Med 2004;32:132-6.
- Montgomery C, Speake BK, Cameron A, et al. Maternal docosahexaenoic acid supplementation and fetal accretion. Br J Nutr 2003;90:135-45. DOI
- Lauritzen L, Hoppe C, Straarup EM, Michaelsen KF. Maternal fish oil supplementation in lactation and growth during the first 2.5 years of life. Pediatr Res 2005;58:235-42. PubMed
- Hawkes JS, Bryan DL, Makrides M, et al. A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha. Am J Clin Nutr 2002;75:75
- Uauy R, Hoffman DR, Mena P, et al. Term infant studies of DHA and ARA supplementation on neurodevelopment: Results of randomized controlled trials. J Pediatr 2003;143:S17-25. PubMed
- Decsi, T., Campoy, C., and Koletzko, B. Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial. Adv.Exp Med Biol 2005;569:109-113. PubMed
- Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B., and Beilin, L. J. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension 1999;34(2):253-260. PubMed
- Otto, S. J., van Houwelingen, A. C., and Hornstra, G. The effect of supplementation with docosahexaenoic and arachidonic acid derived from single cell oils on plasma and erythrocyte fatty acids of pregnant women in the second trimester. Prostaglandins Le PubMed
- Helland, I. B., Saugstad, O. D., Smith, L., Saarem, K., Solvoll, K., Ganes, T., and Drevon, C. A. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. Pediatrics 2001;108(5):E82. PubMed
- Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., and Raederstorff, D. The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am.J.Clin.Nutr. 2002;76(2):326-330. PubMed
- Woodman, R. J., Mori, T. A., Burke, V., Puddey, I. B., Barden, A., Watts, G. F., and Beilin, L. J. Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients PubMed
- Jensen, C. L., Voigt, R. G., Prager, T. C., Zou, Y. L., Fraley, J. K., Rozelle, J. C., Turcich, M. R., Llorente, A. M., Anderson, R. E., and Heird, W. C. Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment in breastfed
- Theobald, H. E., Goodall, A. H., Sattar, N., Talbot, D. C., Chowienczyk, P. J., and Sanders, T. A. Low-dose docosahexaenoic acid lowers diastolic blood pressure in middle-aged men and women. J Nutr 2007;137(4):973-978.
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See these in context on the Docosahexaenoic Acid (dha) monograph →
Perilla 4 references
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