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Dietary supplement

Phosphatidyl Serine Powder Ingredients & Drug Interactions

by Herbadiet

Phosphatidyl Serine Powder label
See full label image
Powder Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Phosphatidyl Serine Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Phosphatidyl Serine Powder is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Phosphatidyl Serine Powder by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Phosphatidyl Serine Powder by Herbadiet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Phosphatidyl Serine Powder by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: phosphatidylserine, a compound found naturally in cell membranes throughout your body. It's derived from plant sources and supplied here as a powder.

There are no other inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Cognitive health support.
  • We looked for evidence on: Age-related cognitive decline, Cognitive function, Attention deficit-hyperactivity disorder (ADHD), Memory, Mental performance, Brain function.
  • The strongest evidence on file: Phosphatidylserine is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer disease, based on the data we hold. For athletic performance, cognitive function, ADHD, and dementia, the evidence isn't established enough to rate it either way.

If you're considering this supplement for one of those other uses, there's not yet a solid scientific case we can point to.

The evidence, ingredient by ingredient Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylserine is generally well tolerated when taken by mouth, but long-term safety hasn't been fully studied. The most common side effects are flatulence, stomach upset, headache, insomnia, and nausea—and insomnia is more likely at higher doses around 600 mg.

Gastrointestinal upset can show up at 200–300 mg per day. There isn't enough safety data for pregnancy, so it's best to avoid it if you're pregnant.

Safety while breastfeeding is also unknown, so avoidance is recommended during that time too. Talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticholinergic drugs (used for overactive bladder, motion sickness, or other conditions) or cholinergic drugs (used to boost acetylcholine activity), double-check with your doctor or pharmacist before adding this product. Both types have Moderate interactions with phosphatidylserine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Phosphatidyl Serine Powder may help with age-related cognitive decline or Alzheimer disease, but the evidence for other brain or performance uses isn't clear yet. If you take anticholinergic or cholinergic medications, check with your doctor or pharmacist before starting this product.

It's generally well tolerated but can cause stomach upset or sleep issues at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phosphatidyl Serine Powder, straight from the product label.

Brand Herbadiet
Net contents 0 Not Present
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 293511
Product type Fat/fatty Acid
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phosphatidyl Serine Powder by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
100 mg
Maximum serving Sizes:
200 mg
IngredientAmount% DV
Phosphatidylserine, Powder100 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Cognitive health support Functional active ingredient Derived from soya lecithin

Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast

Being a natural produce, there can be minor color variations because of geographical & seasonal variation of the raw material. Herbal extracts can be hygroscopic & may agglomerate at times. This, in no way, affect the efficacy of the product.

Vegan

Ethically sourced Scientifically tested Premium grade ingredients

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary Supplement, take up to 200 mg, or as described by your physician

Precautions

Keep out of reach of children.

Pregnant or lactating women should consult your physician before use.

Storage

Store in a dry, cool & dark.

FDA Disclaimer Statement

Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

FSSAI (Food Safety and Standards Authority of India) Lic. No: 20817018000147

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Phosphatidyl Serine Powder by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Phosphatidyl Serine Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Phosphatidyl Serine Powder by Herbadiet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size100 mg Dosage formPowder Amounts shown are per serving.

Phosphatidylserine, Powder

Interacts with
219 drugs
100 mg per serving Form: Soy Lecithin

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Phosphatidylserine, Powder monograph & interactions
Interaction report

Phosphatidyl Serine Powder by Herbadiet Drug Interactions

Want to check YOUR meds against Phosphatidyl Serine Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Phosphatidylserine, Powder 219

Individual Drug Interactions

The ingredients in Phosphatidyl Serine Powder interact with 219 drugs. Click any drug to see the details.

1 of the 1 ingredient in Phosphatidyl Serine Powder interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Phosphatidyl Serine Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Phosphatidylserine, Powder2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Phosphatidylserine, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Phosphatidyl Serine Powder, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
Street Address
11, Sector - 14
City
Rohtak
State
Haryana
ZipCode
124001
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Phosphatidyl Serine Powder by Herbadiet: Common Questions

Does Phosphatidyl Serine Powder by Herbadiet interact with any medications?
Yes. Based on its ingredients, Phosphatidyl Serine Powder has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Phosphatidyl Serine Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What dose might cause insomnia or stomach problems?
Insomnia is more likely at higher doses around 600 mg. Stomach upset like flatulence or nausea can start at 200–300 mg per day. Start lower if you're new to it and see how you feel.
Can I take this while I'm pregnant or breastfeeding?
There isn't enough safety data during pregnancy, so avoidance is recommended. Safety while breastfeeding is unknown too. Talk with your doctor or pharmacist—they can help you weigh the pros and cons for your situation.
What is phosphatidylserine and what does it do?
Phosphatidylserine is a compound found naturally in cell membranes. It's thought to support brain health by affecting how your cells communicate, particularly by raising levels of acetylcholine, a brain chemical involved in memory and thinking.
Does this actually work for memory or brain function?
It's possibly effective for age-related cognitive decline and Alzheimer disease based on the data we hold. For other uses like ADHD or general cognitive function, the evidence isn't established yet.
What are the most common side effects?
Flatulence, stomach upset, headache, insomnia, and nausea are the most common. They're mild in most studies, but insomnia and stomach symptoms can depend on your dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phosphatidyl Serine Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phosphatidyl Serine Powder label
Go deeper

The Full Monographs Behind Phosphatidyl Serine Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph →
Sources

Sources & How We Checked

Phosphatidyl Serine Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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