Phosphatidylserine Complex Ingredients & Drug Interactions
by Country Life
What is this page for?
First and foremost: checking Phosphatidylserine Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phosphatidylserine Complex is a dietary supplement by Country Life with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sharp-PS Green. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Phosphatidylserine Complex by Country Life
Ask about any prescription or over-the-counter medication and we check it for interactions with Phosphatidylserine Complex by Country Life — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Phosphatidylserine Complex by Country Life
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This product contains two active ingredients: sunflower lecithin and phosphatidylserine (delivered as Sharp-PS Green). Both are phospholipids — naturally occurring compounds that support cell membrane structure and function.
The softgel capsule also contains several inactive ingredients including gelatin, glycerin, purified water, silica, mixed tocopherols, and ascorbyl palmitate to hold everything together and preserve the formula.
Does it work?
Moderate evidence
Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer disease, though the evidence is still building. Sunflower lecithin, by contrast, shows likely ineffective evidence for Alzheimer disease and insufficient evidence for age-related cognitive decline, anxiety, bipolar disorder, and other conditions.
Neither ingredient has solid evidence for athletic performance, ADHD, or general cognitive function, so the data we hold doesn't establish those claims.
How safe is it?
Well-documented data
Both ingredients are generally well tolerated. The most common side effects are gastrointestinal — nausea, flatulence, diarrhea, abdominal pain, and a feeling of fullness.
Phosphatidylserine can also cause headache and insomnia, especially at higher doses (600 mg or above). Sunflower lecithin may trigger allergic skin reactions in people with egg or soy allergies.
For pregnancy and breastfeeding: Sunflower lecithin is likely safe during both. Phosphatidylserine has insufficient safety data — the facts advise avoiding it during pregnancy and breastfeeding.
Talk with your doctor or pharmacist before using this product if you're pregnant, nursing, or planning to be.
Meds to double-check
Moderate interaction found
Check with your pharmacist before taking this product if you use anticholinergic drugs (for overactive bladder, muscle spasms, or other conditions) or cholinergic drugs (for myasthenia gravis or Alzheimer disease) — both are Moderate-severity interactions. The phosphatidylserine in this formula may theoretically interfere with how these medications work.
The bottom line
Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help if you're concerned about age-related cognitive changes or early Alzheimer disease, since phosphatidylserine shows some promise there. If you take anticholinergic or cholinergic medications, check with us or your pharmacist first — the interaction could affect how well your drugs work.
Not recommended during pregnancy or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phosphatidylserine Complex, straight from the product label.
| Brand | Country Life |
|---|---|
| Barcode (UPC) | 015794017172 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 326832 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phosphatidylserine Complex by Country Life, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sunflower Lecithin | 0 NP | -- |
| Phosphatidylserine | 100 mg | -- |
| Sharp-PS Green | 556 mg | -- |
Other ingredients: Bovine Gelatin, Glycerin, Water, Purified, Silica, Mixed Tocopherols, Ascorbyl Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Phosphatidylserine is one of the major lipids found in the brain and plays an important role in the function of brain and nerve cell membranes. Sharp PS Green phosphatidylserine supports healthy brain function and brain health.
Country Life's Phosphatidylserine uses the Non-GMO, soy free, and eco-friendly, Sharp PS Green ingredient derived from sunflower lecithin.
Yes Certified Gluten-Free by GFCO.org No yeast, corn or wheat No soy, milk or salt No sugar or preservatives No artificial colors, flavors or sweeteners No magnesium stearate
Yes Manufacturing supports wind power This product has been manufactured at a GMP Registered facility.
Certified Gluten-Free
Supports brain function and health
Our Pledge of Integrity Authenticity Cleanliness Freshness Consistency Accuracy
100% bovine gelatin, BSE-free.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Yes Recyclable Packaging
Brand IP Statement(s)
Sharp PS is a registered trademark of Enzymotec Ltd.
Established 1971 Country Life
Seals/Symbols
Certified B Corporation GFCO.org (Gluten-Free Certification Organization)
Formula
Phosphatidylserine Complex From Sunflower Lecithin Including the Non-GMO, Sharp PS green ingredient
100% bovine gelatin, BSE-free.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults take one (1) softgel three (3) times daily with food or as directed by a health care professional.
Precautions
As a reminder, discuss the supplements and medications that you take with your health care providers. Caution: If you are pregnant, nursing, or taking medication, have a medical condition or planning surgery, consult a doctor before using this product.
Stop using and consult a doctor if any adverse reactions occur. Do not accept if seal is broken.
Keep out of the reach of children.
Storage
Store between 59 degrees - 86 degrees F.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phosphatidylserine Complex by Country Life label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phosphatidylserine Complex by Country Life
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.
Sharp-PS Green
Interacts with219 drugs
Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...
Sharp-PS Green monograph & interactionsOther (inactive) ingredients: Bovine Gelatin, Glycerin, Water, Purified, Silica, Mixed Tocopherols, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.
Phosphatidylserine Complex by Country Life Drug Interactions
HelloPharmacist Interaction Report
Phosphatidylserine Complex by Country Life contains phosphatidylserine, which has documented interactions with two medication types.
The most serious concern is with anticholinergic drugs (Moderate severity) — medications used for conditions like overactive bladder, muscle spasms, and certain types of poisoning. Phosphatidylserine may increase acetylcholine levels, which could theoretically decrease how well these drugs work.
Read the full breakdown — every affected drug type, severity by severity
Additionally, phosphatidylserine may have additive effects with cholinergic drugs (Moderate severity) — medications that boost acetylcholine activity, sometimes used for myasthenia gravis or Alzheimer disease. The combination could theoretically amplify cholinergic effects.
Sunflower lecithin, the product's other active ingredient, has no documented interactions in our data.
Altogether, these interactions span 218 individual medications. If you take any anticholinergic or cholinergic medication, run it through the checker below before adding this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Phosphatidylserine Complex?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Phosphatidylserine Complex interact with 219 drugs. Click any drug to see the details.
1 of the 1 ingredient in Phosphatidylserine Complex interact with drugs. Each result below shows which ingredient is responsible. Sharp-PS Green
AcepromazineAtravet
How Acepromazine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acepromazine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetylcholineMiochol-E
How Acetylcholine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full Sharp-ps Green + Acetylcholine interactionAclidinium BromideTudorza Pressair
How Aclidinium Bromide interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Aclidinium Bromide interactionAclidinium Bromide, Formoterol Fumarate DihydrateDuaklir Pressair
How Aclidinium Bromide, Formoterol Fumarate Dihydrate interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Aclidinium Bromide, Formoterol Fumarate Dihydrate interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAmantadineGocovri, Osmolex ER, Symmetrel
How Amantadine interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps Green + Amantadine interactionAmbenonium ChlorideMytelase
How Ambenonium Chloride interacts with Phosphatidylserine Complex — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps GreenCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full Sharp-ps Green + Ambenonium Chloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Phosphatidylserine Complex with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Sharp-PS Green
Anticholinergic Drugs
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.
Cholinergic Drugs
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.
Brand information
Manufacturer and brand details for Phosphatidylserine Complex, from the product label.
Country Life
See all Country Life products- Name
- Country Life, LLC
- Street Address
- 180 Vanderbilt Motor Parkway
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Web Address
- CountryLifeVitamins.com
Phosphatidylserine Complex by Country Life: Common Questions
Does Phosphatidylserine Complex by Country Life interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this product safe to take while I'm pregnant or breastfeeding?
What's the difference between sunflower lecithin and phosphatidylserine?
Can this help with ADHD or general brain fog?
What side effects should I watch for?
How much phosphatidylserine is in each capsule?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phosphatidylserine Complex is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phosphatidylserine Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Phosphatidylserine
Interacts with 219 drugsPhosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...
Read the full Phosphatidylserine monograph → Herb & supplement monographLecithin
Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...
Read the full Lecithin monograph →Sources & How We Checked
Phosphatidylserine Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lecithin 9 references
- Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
- Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
- Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
- Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
- Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
- Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
- Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:
Phosphatidylserine 9 references
- Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
- Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
- Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
- Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
- Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
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