Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Phyto-Gen Tonic-gen Ingredients & Drug Interactions

by Genestra Brands

Phyto-Gen Tonic-gen label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Phyto-Gen Tonic-gen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Phyto-Gen Tonic-gen is a dietary supplement by Genestra Brands with 3 active ingredients. Its ingredients are commonly taken for dry eyes and eye strain, joint pain and inflammation, immune and general wellness support.Based on those ingredients, 140 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Currant (Ribes nigrum) bud extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Phyto-Gen Tonic-gen by Genestra Brands

Ask about any prescription or over-the-counter medication and we check it for interactions with Phyto-Gen Tonic-gen by Genestra Brands — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Phyto-Gen Tonic-gen by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Phyto-Gen Tonic-gen contains 3 active plant extracts: oak bud, black currant bud, and giant sequoia young shoot, each in a liquid form. The inactive ingredients are water, purified ethanol, and glycerin — standard carriers for herbal liquids.

There are no fillers or binders in this formula.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Black Currant product and its label doesn't state a use — see Black Currant's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The black currant extract in this product has been studied for several conditions — Alzheimer disease, liver disease, common cold, cough, and atopic dermatitis (eczema) — but the evidence isn't strong enough to rate it as effective for any of them. We don't have effectiveness data on file for the oak bud extract or giant sequoia extract.

If you're considering this product for a specific health concern, talk with your doctor or pharmacist about whether the supporting evidence fits your needs.

The evidence, ingredient by ingredient Black Currant

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black currant in food amounts is generally well tolerated. Concentrated supplements like this one are less studied, so use caution and check with your doctor first.

In one trial, 8 out of 2,154 people taking black currant seed oil reported mild diarrhea 2 to 10 days after starting; this is a small number of trial participants. We don't have pregnancy or lactation safety data for any of the three extracts in this product — talk with your doctor or pharmacist about whether it's appropriate for you if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Black Currant

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Black Currant.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 140 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel, and others) — black currant may increase bleeding risk. Also double-check if you take antipsychotic medications (phenothiazines) — there's a moderate-severity concern about seizure risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a concentrated herbal liquid with three plant extracts, two of which we cannot yet check for interactions. If you take blood thinners, antiplatelet drugs, or antipsychotics, this product isn't a fit — black currant raises bleeding and seizure risk.

Even if you don't take those medications, run your full medication list through the checker here, then confirm with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phyto-Gen Tonic-gen, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 883196117017
Net contents 0.5 Fluid Ounce(s); 15 mL
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 264505
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phyto-Gen Tonic-gen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.28 mL
Maximum serving Sizes:
0.28 mL
Servings per container
53
UPC/BARCODE
883196117017
IngredientAmount% DV
Oak (Quercus robur) bud extract0.09 mL--
Black Currant (Ribes nigrum) bud extract0.09 mL--
Giant Sequoia (Sequoia gigantea) young shoot extract0.09 mL--

Other ingredients: Water, Purified, Ethanol, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Take 10 drops once daily or as recommended by your health professional. Invert bottle to 45 degrees and shake lightly allowing drops to fall directly into mouth or in 1/4 oz of water.

Precautions

For warnings and additional information, see outer box.

Keep out of the reach of children.

Use only if safety seal is intact.

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

Storage

Store in a cool, dry place.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Scan to learn about our quality excellence V2 934-15U

FDA Statement of Identity

Dietary Supplement

Formula

Oak Giant Sequoia Black Currant

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Phyto-Gen Tonic-gen by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Phyto-Gen Tonic-gen label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Phyto-Gen Tonic-gen by Genestra Brands

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Oak (Quercus robur) bud extract

0.09 mL per serving

Black Currant (Ribes nigrum) bud extract

Interacts with
140 drugs
0.09 mL per serving

Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjo...

Black Currant (Ribes nigrum) bud extract monograph & interactions

Giant Sequoia (Sequoia gigantea) young shoot extract

0.09 mL per serving

Other (inactive) ingredients: Water, Purified, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phyto-Gen Tonic-gen by Genestra Brands Drug Interactions

Want to check YOUR meds against Phyto-Gen Tonic-gen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
140Drugs
140 Moderate

Ingredients driving the most interactions

Black Currant (Ribes nigrum) bud extract 140

Individual Drug Interactions

The ingredients in Phyto-Gen Tonic-gen interact with 140 drugs. Click any drug to see the details.

1 of the 3 ingredients in Phyto-Gen Tonic-gen interact with drugs. Each result below shows which ingredient is responsible. Black Currant (Ribes nigrum) bud extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Phyto-Gen Tonic-gen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Currant (Ribes nigrum) bud extract2 drug types · 140 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Gamma-linolenic acid (GLA), a constituent of black currant seed oil, appears to have antiplatelet effects.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, black currant seed oil might increase the risk of seizure in patients receiving phenothiazines.
Black currant seed oil contains gamma-linolenic acid (GLA). There is some concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines, although there is no evidence that black currant seed oil causes seizures. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with GLA, although none experienced an actual seizure. In another report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily, which contains GLA, was added. One of these patients had a prior history of seizures.

Likelihood Possible Evidence D
Black Currant (Ribes nigrum) bud extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Phyto-Gen Tonic-gen, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Phyto-Gen Tonic-gen by Genestra Brands: Common Questions

Does Phyto-Gen Tonic-gen by Genestra Brands interact with any medications?
Yes. Based on its ingredients, Phyto-Gen Tonic-gen has a known interaction with 140 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Phyto-Gen Tonic-gen contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is black currant safe in supplements?
The berry itself in food is fine, but concentrated supplements are less well studied. Safety data is limited, so it's wise to check with your doctor or pharmacist before taking this product, especially if you have any health conditions or take medications.
Can this product cause diarrhea?
Mild diarrhea was reported by a small number of people (8 out of 2,154) taking black currant seed oil in a trial, usually 2 to 10 days after they started. It's uncommon, but it can happen.
Is there proof this works for colds or cough?
The black currant extract here has been studied for common cold and cough, but there isn't enough reliable evidence to say it's effective for either one. The data we hold rates it as insufficient evidence.
Can I take this while pregnant or breastfeeding?
We don't have enough safety data on file for any of the three plant extracts in this product during pregnancy or breastfeeding. Talk with your doctor or pharmacist to decide whether it's right for you.
What are the inactive ingredients?
Water, purified ethanol (alcohol), and glycerin — these are standard carriers for liquid herbal extracts and make up the base of the formula. There are no fillers or binders added.
Can you check if this works for liver disease?
Black currant has been studied for liver disease, but the evidence isn't reliable enough to rate it as effective. If liver health is your concern, ask your doctor whether this product makes sense for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phyto-Gen Tonic-gen is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phyto-Gen Tonic-gen label
Go deeper

The Full Monographs Behind Phyto-Gen Tonic-gen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Currant

Interacts with 140 drugs

Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjoyed safely as a food and is popular as a...

Read the full Black Currant monograph →
Sources

Sources & How We Checked

Phyto-Gen Tonic-gen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Currant 6 references
  1. Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty A PubMed
  2. Fa-lin Z, Zhen-yu W, Yan H, et al. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. Phytother Res 2010;24 Suppl 2:S209-13. PubMed
  3. Holman CP and Bell AF. A trial of evening primrose oil in the treatment of chronic schizophrenia. J Orhtomolecular Psych 1983;12:302-304.
  4. Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. PubMed
  5. Norred, C. L. and Brinker, F. Potential coagulation effects of preoperative complementary and alternative medicines. Alt Ther 2001;7(6):58-67.
  6. Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3. PubMed

See these in context on the Black Currant monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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