Pine Bark Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pine Bark Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pine Bark Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for circulation and vein health, antioxidant support, skin health and aging.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pine Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Pine Bark Extract by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Pine Bark Extract by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Pine Bark Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Pine Bark Extract, a standardized botanical derived from maritime pine. The powder form contains no inactive ingredients or fillers listed.
Does it work?
Moderate evidence
Pine Bark Extract carries a "Possibly Effective" rating for osteoarthritis and chronic venous insufficiency (heaviness or swelling in the legs due to sluggish blood flow in the veins). For asthma, the evidence is also "Possibly Effective." For high cholesterol (hyperlipidemia), the data we hold rates it "Possibly Ineffective," meaning the evidence does not support a benefit.
How safe is it?
Well-documented data
Pine Bark Extract is generally well tolerated in studies, though long-term safety hasn't been fully established. The most common side effects reported are gastrointestinal complaints, dizziness, and vertigo.
Headache and severe dizziness have been noted in some trials. Rarely, chest pain and worsening heart failure have been reported in individual patients, though it's unclear whether the extract was directly responsible.
During pregnancy, there isn't enough safety data, so it's best avoided. The same applies to breastfeeding—insufficient information exists to know either way, so talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Before you start, double-check any blood thinners or antiplatelet drugs you're taking—this extract may increase bleeding risk. If you're on diabetes medications, monitor your blood sugar closely and watch for signs of low blood sugar (hypoglycemia).
Finally, if you take immunosuppressants, discuss this supplement with your pharmacist, as it may reduce their effectiveness.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Pine Bark Extract may help with osteoarthritis, chronic leg swelling from poor vein function, or asthma symptoms—evidence is modest but promising. If you take blood thinners, diabetes medications, or immunosuppressant drugs, check with your pharmacist first.
Pregnant and breastfeeding women should avoid it unless their doctor says otherwise.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pine Bark Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X000HUM6ID |
| Net contents | 250 Gram(s); 8.8 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2024 |
| DSLD ID | 311439 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pine Bark Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pine Bark Extract | 250 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Bulksupplements.com Clean & pure bulk supplements
Formulation
Free of: Added sugar, soy, dairy, gluten, additives
Color may vary
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take 250 mg (1/10 tsp) daily, or as directed by a physician.
General Statements
Use an accurate milligram scale.
New
Storage
Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pine Bark Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pine Bark Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size250 Milligram(s) Dosage formPowder Servings per container1000 Amounts shown are per serving.
Pine Bark Extract
Interacts with327 drugs
Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research...
Pine Bark Extract monograph & interactionsPine Bark Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Pine Bark Extract by BulkSupplements.com carries documented interactions with three main medication types.
The most serious concern is with blood thinners and antiplatelet drugs (medications that prevent clotting): because pine bark extract may inhibit platelet aggregation, it could theoretically raise your bleeding risk when combined with these drugs. The clinical significance of this effect remains unclear, but it's worth discussing with your doctor if you're on any anticoagulant or antiplatelet medication.
Read the full breakdown — every affected drug type, severity by severity
Two additional Moderate interactions exist. Pine bark extract may interfere with immunosuppressant drugs (used after transplants or for certain autoimmune conditions) by stimulating immune activity instead—though this effect has only been shown in lab and animal studies, not yet in people.
Additionally, it could increase the risk of low blood sugar (hypoglycemia) when paired with diabetes medications; one clinical study showed the extract lowers blood glucose in patients already taking diabetes drugs, so close monitoring and possible dose adjustments might be necessary.
Altogether, these interactions span 322 individual medications. Use the medication checker on this page to look up your specific prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Pine Bark Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Pine Bark Extract interact with 327 drugs. Click any drug to see the details.
1 of the 1 ingredient in Pine Bark Extract interact with drugs. Each result below shows which ingredient is responsible. Pine Bark Extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Alemtuzumab interactionAlogliptinNesina
How Alogliptin interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with Pine Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Anisindione interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Pine Bark Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Pine Bark Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Clinical research suggests that maritime pine bark extract inhibits platelet aggregation. However, the clinical significance of this effect is unclear.
Antidiabetes Drugs
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
One clinical study shows that maritime pine bark extract decreases blood sugar in patients with diabetes being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Immunosuppressants
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
In vitro and animal research suggests that maritime pine bark extract has immunostimulant activity. This effect has not been reported in humans.
Brand information
Manufacturer and brand details for Pine Bark Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Pine Bark Extract by BulkSupplements.com: Common Questions
Does Pine Bark Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does Pine Bark Extract work for joint pain?
Is it safe to take Pine Bark Extract long-term?
What are the most common side effects?
Can I take this if I'm pregnant?
What does this extract do for chronic leg swelling?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pine Bark Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pine Bark Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pine Bark Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 14 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Maritime Pine 14 references
- Rice-Evans CA, Packer L, eds. Flavonoids in Health and Disease. Manhattan, NY: Marcel Dekker, Inc., 1998.
- Liu FJ, Zhang YX, Lau BH. Pycnogenol enhances immune and haemopoietic functions in senescence-accelerated mice. Cell Mol Life Sci 1998;54:1168-72. PubMed
- Putter M, Grotemeyer KH, Wurthwein G, et al. Inhibition of smoking-induced platelet aggregation by aspirin and pycnogenol. Thromb Res 1999;95:155-61. PubMed
- Kohama T, Inoue M. Pycnogenol alleviates pain associated with pregnancy. Phytother Res 2006;20:232-4.
- Liu X, Zhou HJ, Rohdewald P. French maritime pine bark extract pycnogenol dose-dependently lowers glucose in type 2 diabetic patients (letter). Diabetes Care 2004;27:839. PubMed
- Liu X, Wei J, Tan F, et al. Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II. Life Sci 2004;75:2505-13. PubMed
- Wilson D, Evans M, Guthrie N et al. A randomized, double-blind, placebo-controlled exploratory study to evaluate the potential of pycnogenol for improving allergic rhinitis symptoms. Phytother Res 2010;24:1115-9.
- Araghi-Niknam, M., Hosseini, S., Larson, D., Rohdewald, P., and Watson, R. R. Pine bark extract reduces platelet aggregation. Integr.Med. 3-21-2000;2(2):73-77. PubMed
- Trebaticka, J., Kopasova, S., Hradecna, Z., Cinovsky, K., Skodacek, I., Suba, J., Muchova, J., Zitnanova, I., Waczulikova, I., Rohdewald, P., and Durackova, Z. Treatment of ADHD with French maritime pine bark extract, Pycnogenol. Eur.Child Adolesc.Psychi PubMed
- Suzuki, N., Uebaba, K., Kohama, T., Moniwa, N., Kanayama, N., and Koike, K. French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study
- Cisar, P., Jany, R., Waczulikova, I., Sumegova, K., Muchova, J., Vojtassak, J., Durackova, Z., Lisy, M., and Rohdewald, P. Effect of pine bark extract (Pycnogenol) on symptoms of knee osteoarthritis. Phytother.Res. 2008;22(8):1087-1092.
- Enseleit, F., Sudano, I., Periat, D., Winnik, S., Wolfrum, M., Flammer, A. J., Frohlich, G. M., Kaiser, P., Hirt, A., Haile, S. R., Krasniqi, N., Matter, C. M., Uhlenhut, K., Hogger, P., Neidhart, M., Luscher, T. F., Ruschitzka, F., and Noll, G. Effects
- Schoonees, A., Visser, J., Musekiwa, A., and Volmink, J. Pycnogenol(R) (extract of French maritime pine bark) for the treatment of chronic disorders. Cochrane.Database.Syst.Rev. 2012;4:CD008294.
- Wang S, Tan D Zhao Y et al. The effect of pycnogenol on the microcirculation, platelet function and ischemic myocardium in patients with coronary artery diseases. Eur Bull Drug Res 1999;7:19-25.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC