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Dietary supplement

Pomegranate Extract 40% Ellagic Acid Ingredients & Drug Interactions

by BulkSupplements.com

Pomegranate Extract 40% Ellagic Acid label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pomegranate Extract 40% Ellagic Acid against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pomegranate Extract 40% Ellagic Acid is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, general anti-aging or 'cleanse' products, cancer prevention interest.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ellagic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: ellagic acid, a compound derived from pomegranate extract at 40% concentration. Ellagic acid is a polyphenol — a type of plant chemical — that your body encounters in small amounts through foods like pomegranates, berries, and nuts.

There are no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ellagic Acid product and its label doesn't state a use — see Ellagic Acid's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for ellagic acid isn't established in the data we hold. We have insufficient reliable evidence to rate it for bladder cancer, prostate cancer, cognitive function, diabetes, melasma, or polycystic ovary syndrome (PCOS).

That doesn't mean it doesn't work — it means rigorous human studies are lacking, so we can't say one way or the other.

The evidence, ingredient by ingredient Ellagic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ellagic acid from food sources is generally considered safe, but concentrated supplements like this one aren't well studied in humans at supplement doses. The safety information available advises caution or avoidance of concentrated supplements.

In one clinical trial combining ellagic acid with another herb, a small number of participants reported nausea and diarrhea severe enough to stop taking it, though it's unclear whether ellagic acid alone caused these effects. Pregnancy and lactation safety data isn't on file for this ingredient — talk with your doctor or pharmacist before using it if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Ellagic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ellagic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood sugar medications (antidiabetes drugs like metformin) with your doctor or pharmacist before taking this product. Ellagic acid may lower blood sugar levels, which could increase your risk of low blood sugar when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This single-ingredient supplement may appeal to people looking for the polyphenols in pomegranate, but the evidence for what it actually does isn't established yet. If you take blood sugar medication, check with your doctor or pharmacist first — ellagic acid may lower blood sugar further.

Because concentrated supplements of this type are understudied in humans, it's worth a conversation with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pomegranate Extract 40% Ellagic Acid, straight from the product label.

Brand BulkSupplements.com
Net contents 500 Gram(s); 17.64 Ounce(s)
Market status On market
Date entered into DSLD Sep 24, 2021
DSLD ID 254238
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
750 mg
Maximum serving Sizes:
750 mg
Servings per container
665
IngredientAmount% DV
Ellagic Acid300 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & Pure Bulk Supplements

US Standard Measuring Spoons Spoon size (level) milligrams 1/8 teaspoon 391 1/4 teaspoon 782 1/2 teaspoon 1564

Precautions

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women. Consult your physician before use.

Keep out of reach of children!

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Free of: Sugar, soy, dairy, yeast, gluten, or additives

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 750 mg (scant 1/4 tsp) twice daily, or as directed by a physician.

Storage

Storage: keep dry, cool & dark

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pomegranate Extract 40% Ellagic Acid label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size750 mg Dosage formPowder Servings per container665 Amounts shown are per serving.

Ellagic Acid

Interacts with
86 drugs
300 mg per serving

Ellagic acid is a natural plant compound (a polyphenol) found in foods like pomegranates, raspberries, strawberries, and walnuts. It is studied mostly...

Ellagic Acid monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Pomegranate Extract 40% Ellagic Acid?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Ellagic Acid 86

Individual Drug Interactions

The ingredients in Pomegranate Extract 40% Ellagic Acid interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pomegranate Extract 40% Ellagic Acid interact with drugs. Each result below shows which ingredient is responsible. Ellagic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Pomegranate Extract 40% Ellagic Acid with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Ellagic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Some clinical research shows that ellagic acid reduces fasting and postprandial glucose levels in patients with type 2 diabetes who are on stable doses of hypoglycemic agents such as metformin. Theoretically, taking ellagic acid with antidiabetes drugs might increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Ellagic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pomegranate Extract 40% Ellagic Acid, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Road
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com: Common Questions

Does Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Pomegranate Extract 40% Ellagic Acid has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pomegranate Extract 40% Ellagic Acid contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does ellagic acid actually lower blood sugar?
Clinical research does show that ellagic acid can reduce fasting and postprandial (after-meal) blood sugar levels in people with type 2 diabetes who are already on stable doses of blood sugar medications. That's why there's a Moderate interaction concern if you take antidiabetes drugs — the combination could push your levels too low.
What's the difference between ellagic acid from food and from a concentrated supplement?
You get small amounts of ellagic acid naturally from pomegranates, berries, and nuts, and those food amounts are considered safe. But this product is a concentrated supplement dose, and we simply don't have much human safety data on those doses yet. That's why the label advises caution or avoidance.
What side effects have been reported?
In one clinical trial combining ellagic acid with graviola (another herb), a small number of participants experienced nausea and diarrhea bad enough to stop taking it. It's not clear whether ellagic acid alone caused these effects or if the combination was responsible.
Is this supplement proven to work for cancer or any other condition?
We have insufficient reliable evidence to rate ellagic acid for bladder cancer, prostate cancer, diabetes, or the other conditions listed — including cognitive function, melasma, and PCOS. That means rigorous human studies backing these uses are lacking.
Is it safe to use during pregnancy or breastfeeding?
We don't have safety information on file for ellagic acid in pregnancy or lactation. Talk with your doctor or pharmacist before using this supplement if you're pregnant or breastfeeding — they can help you weigh what's known.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pomegranate Extract 40% Ellagic Acid is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pomegranate Extract 40% Ellagic Acid label
Go deeper

The Full Monographs Behind Pomegranate Extract 40% Ellagic Acid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ellagic Acid

Interacts with 86 drugs

Ellagic acid is a natural plant compound (a polyphenol) found in foods like pomegranates, raspberries, strawberries, and walnuts. It is studied mostly in laboratory and animal research for a...

Read the full Ellagic Acid monograph →
Sources

Sources & How We Checked

Pomegranate Extract 40% Ellagic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ellagic Acid 9 references
  1. Ertam I, Mutlu B, Unal I, Alper S, Kivçak B, Ozer O. Efficiency of ellagic acid and arbutin in melasma: a randomized, prospective, open-label study. J Dermatol. 2008;35(9):570-4. PubMed
  2. Dahl A, Yatskayer M, Raab S, Oresajo C. Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone. J Drugs Dermatol. 2013;12(1):52-8.
  3. Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate. Eur Urol. 2005;47(4):449-54 PubMed
  4. Le Donne M, Lentini M, Alibrandi A, et al. Antiviral activity of Ellagic acid and Annona Muricata in cervical HPV related pre-neoplastic lesions: A randomized trial. J Funct Food 2017;35:549-54. DOI
  5. Liu Y, Yu S, Wang F, et al. Chronic administration of ellagic acid improved the cognition in middle-aged overweight men. Appl Physiol Nutr Metab. 2018;43(3):266-73. PubMed
  6. Serretta V, Berardinis E, Simonato A, et al. A prospective observational study on oral administration of Ellagic Acid and Annona Muricata in patients affected by non-muscle invasive bladder cancer not undergoing maintenance after 6-week intravesical proph
  7. Ghadimi M, Foroughi F, Hashemipour S, et al. Randomized double-blind clinical trial examining the Ellagic acid effects on glycemic status, insulin resistance, antioxidant, and inflammatory factors in patients with type 2 diabetes. Phytother Res 2021;35(2) PubMed
  8. Kazemi M, Lalooha F, Nooshabadi MR, Dashti F, Kavianpour M, Haghighian HK. Randomized double blind clinical trial evaluating the Ellagic acid effects on insulin resistance, oxidative stress and sex hormones levels in women with polycystic ovarian syndrome PubMed
  9. Ghadimi M, Foroughi F, Hashemipour S, et al. Decreased insulin resistance in diabetic patients by influencing Sirtuin1 and Fetuin-A following supplementation with ellagic acid: a randomized controlled trial. Diabetol Metab Syndr 2021;13(1):16. PubMed

See these in context on the Ellagic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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