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Dietary supplement

Premier Lecithin Granules Ingredients & Drug Interactions

by Premier Research Labs

Premier Lecithin Granules label
See full label image
Liquid Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Premier Lecithin Granules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Premier Lecithin Granules is a dietary supplement by Premier Research Labs with 2 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Premier Lecithin Granules by Premier Research Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with Premier Lecithin Granules by Premier Research Labs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Premier Lecithin Granules by Premier Research Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Premier Lecithin Granules has 2 active ingredients: potassium and soy lecithin. Soy lecithin is a phospholipid — a type of fat from soybeans — that's commonly used in supplements.

Potassium is an essential mineral your body needs for heart rhythm, muscle function, and nerve signaling. The product contains no other inactive ingredients.

Because this is a liquid form and potassium is a mineral supplement, the concentration matters more than with many other supplements. Even a modest amount of supplemental potassium can push your blood level into a risky range if you're already taking medications that reduce how your kidneys clear it.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: brain and nerve function support.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Parkinson disease, Memory, Cognitive function, Neuroprotection.
  • The closest evidence on file: Lecithin is rated "Likely Ineffective" for Alzheimer disease (Natural Medicines).
  • Also on file: Lecithin is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline, Parkinson disease.

The soy lecithin in this product shows insufficient reliable evidence for most claimed uses — age-related cognitive decline, anxiety, bipolar disorder, and liver health during parenteral nutrition (TPN). For Alzheimer disease, lecithin is rated likely ineffective.

We don't have effectiveness data on the potassium portion of this product in our data.

The evidence, ingredient by ingredient Potassium Lecithin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both potassium and soy lecithin are generally well tolerated when taken by mouth. Common side effects from either ingredient are mild digestive issues — belly pain, diarrhea, nausea, and gas.

The major concern with potassium is that high blood levels can cause serious heart rhythm problems (arrhythmias), heart block, low blood pressure, and confusion; these are rare with normal dietary intake but real with supplements, especially in people with kidney disease. During pregnancy and breastfeeding, dietary potassium is fine, but potassium supplements should only be used under your doctor's guidance.

Soy lecithin is rated likely safe in both pregnancy and breastfeeding; if you have a soy allergy, stop using it and let your healthcare provider know right away. If you have an egg allergy, you should also be aware that lecithin can trigger allergic skin reactions in those with egg sensitivities.

Side effects, ingredient by ingredient Potassium Lecithin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on potassium-sparing diuretics (water pills that keep potassium), ACE inhibitors, or angiotensin receptor blockers (ARBs) — all carry a moderate risk of high blood potassium when combined with this supplement. If you have kidney disease or take any blood pressure medication, mention this product before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Premier Lecithin Granules is not a casual supplement — the potassium content makes it important to check with your own doctor or pharmacist before you start, especially if you take any blood pressure medication, water pills, or have kidney disease. Both ingredients are generally well tolerated at food levels, but supplemental potassium carries real risks if it builds up in your blood.

Talk it over with your healthcare provider before adding this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Premier Lecithin Granules, straight from the product label.

Brand Premier Research Labs
Barcode (UPC) 807735013608
Net contents 10 Ounce(s); 295 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 297541
Product type Fat/fatty Acid
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Premier Lecithin Granules by Premier Research Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Gram(s)
Maximum serving Sizes:
6 Gram(s)
Servings per container
49
UPC/BARCODE
807735013608
IngredientAmount% DV
Calories40 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Potassium80 mg2%
Total Fat4 Gram(s)5%
Saturated Fat1 Gram(s)5%
Soy Lecithin6 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one tablespoon, 2 times daily mixed in food for excellent fatty acid transport or as directed by a health professional. Blends well in smoothies and food

Formula

Premier quality lecithin granules Contains key phosphatidyl complexes for supporting brain and nerve function 100% premier lecithin in granular form (no additives or fillers)

With Phosphatidyl Complexes

We are proud to offer many OU Kosher Certified products.

Precautions

Tamper Seal: Use only if seal is intact.

Consult your health care practitioner if you are pregnant or nursing, taking medications or have a medical condition, before taking this or any other product.

Contains Soy

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Premier nerve and brain support; Fat emulsifier

PRL's Quality Guarantee

NON-GMO No Added Undesirable Excipients Forensic Tested for Adulterants No Radiation Sterilization Heavy Metal Tested

Purity Verified Potency Verified Pathogen Tested by Microbiology FDA-Monitored cGMP Facility

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

OU (Kosher)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Premier Lecithin Granules by Premier Research Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Premier Lecithin Granules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Premier Lecithin Granules by Premier Research Labs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Gram(s) Dosage formLiquid Servings per container49 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Potassium

Interacts with
62 drugs
80 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Soy Lecithin

No known
interactions
6 Gram(s) per serving

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Soy Lecithin monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Premier Lecithin Granules by Premier Research Labs Drug Interactions

Want to check YOUR meds against Premier Lecithin Granules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Premier Lecithin Granules interact with 62 drugs. Click any drug to see the details.

1 of the 2 ingredients in Premier Lecithin Granules interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Premier Lecithin Granules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Premier Lecithin Granules, from the product label.

Premier Research Labs

See all Premier Research Labs products
Name
Premier Research Labs
Pharmacist Counseling Corner

Premier Lecithin Granules by Premier Research Labs: Common Questions

Does Premier Lecithin Granules by Premier Research Labs interact with any medications?
Yes. Based on its ingredients, Premier Lecithin Granules has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Premier Lecithin Granules contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does soy lecithin actually help with memory or Alzheimer disease?
No — lecithin is rated likely ineffective for Alzheimer disease, and the evidence for age-related cognitive decline and other brain uses is too thin to draw conclusions. It's not a proven brain supplement.
What are the most common side effects?
Both potassium and soy lecithin can cause belly pain, diarrhea, nausea, and gas. These are usually mild and digestive in nature when they occur.
Is this safe if I have a soy allergy?
No — soy lecithin is made from soy, so it's not safe for you. Even if you have an egg allergy (not soy), lecithin can trigger allergic skin reactions in some people with egg sensitivities.
Can I use this while pregnant or breastfeeding?
The soy lecithin is rated likely safe during pregnancy and breastfeeding. Potassium from food is fine, but potassium supplements should only be used under your doctor's guidance during pregnancy and breastfeeding — talk to your healthcare provider first.
Why does this product have potassium if it's a lecithin supplement?
The product contains both soy lecithin and potassium as active ingredients — so you're getting both. The potassium is what makes this a riskier supplement if you take certain blood pressure medications, because those drugs already affect your blood potassium level.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Premier Lecithin Granules is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Premier Lecithin Granules label
Go deeper

The Full Monographs Behind Premier Lecithin Granules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Lecithin

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...

Read the full Lecithin monograph →
Sources

Sources & How We Checked

Premier Lecithin Granules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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