Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Primadophilus Kids Cherry Flavored Ingredients & Drug Interactions

by Nature's Way

Primadophilus Kids Cherry Flavored label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Primadophilus Kids Cherry Flavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Primadophilus Kids Cherry Flavored is a dietary supplement by Nature's Way with 3 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus LA-14, Bifidobacterium bifidum lactis Bb-02. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Primadophilus Kids Cherry Flavored by Nature's Way

Ask about any prescription or over-the-counter medication and we check it for interactions with Primadophilus Kids Cherry Flavored by Nature's Way — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Primadophilus Kids Cherry Flavored by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (28 mg) without saying how much of each component you get.

Primadophilus Kids Cherry Flavored contains three active probiotic ingredients: Lactobacillus acidophilus LA-14, Lactobacillus plantarum LP-115, and Bifidobacterium bifidum Bb-02, each supplied as live organisms in a proprietary blend. These are "good" bacteria meant to support digestive and immune health.

The product also includes inactive ingredients like xylitol (sweetener), inulin (a prebiotic fiber), and natural cherry flavoring, along with standard tablet binders and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports healthy digestive flora.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Inflammatory bowel disease (IBD), Irritable bowel syndrome (IBS), Lactose intolerance — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bifidobacterium Bifidum is rated "Possibly Effective" for Irritable bowel syndrome (IBS).

Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, and Helicobacter pylori infection, though the evidence is still developing. It's possibly ineffective for atopic disease (eczema, allergies) and has insufficient evidence for respiratory distress syndrome.

Bifidobacterium bifidum is possibly effective for irritable bowel syndrome and respiratory tract infections, but there's not enough data to know if it helps with hay fever or other conditions like anxiety or Alzheimer disease. We don't have effectiveness data on file for Lactobacillus plantarum.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Bifidum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus and Bifidobacterium bifidum are generally well tolerated in healthy children. However, since these are live microorganisms, there's a small theoretical risk of infection in kids with weakened immune systems — check with your doctor first if your child has immune concerns.

Gastrointestinal side effects like bloating, gas, and abdominal discomfort are uncommon but can happen when starting a probiotic. In rare cases, rashes or itching have been reported in trials, though it's unclear whether the probiotic itself or another ingredient was responsible.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Bifidum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Bifidum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before giving this product, check whether your child is on any antibiotic drugs (Moderate interaction). The medication checker below will tell you if any of your child's other medicines interact with these probiotic strains.

Since we don't have data on Lactobacillus plantarum, also mention to your pharmacist that one of the three ingredients couldn't be fully checked.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Primadophilus Kids is a multi-strain probiotic that may help with digestive issues and IBS in children. It's generally well tolerated but does interact with antibiotics, so timing matters — talk to your pharmacist about spacing doses if your child is on antibiotics.

Kids with weakened immunity should check with their doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Primadophilus Kids Cherry Flavored, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674142431
Net contents 30 Chewable Tablet(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 328028
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Primadophilus Kids Cherry Flavored by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chewable Tablet(s)
Maximum serving Sizes:
1 Chewable Tablet(s)
Servings per container
30
UPC/BARCODE
033674142431
IngredientAmount% DV
Proprietary Probiotic Blend28 mg--
Lactobacillus acidophilus LA-140 NP--
Lactobacillus plantarum LP-1150 NP--
Bifidobacterium bifidum lactis Bb-020 NP--

Other ingredients: Xylitol, Inulin, Hydroxypropyl Cellulose, Stearic Acid, Natural Flavors, Malic Acid, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

3 Billion CFU Probiotic chewables

Ages 2+

Proprietary probiotic blend for kids ages 2+ with Lactobacilli and Bifidobacteria

Specifically formulated for kids

Contains at least 3 billion CFU per serving through date of expiration Blend of 4 probiotic strains

Suggested/Recommended/Usage/Directions

Once daily

Children 2 years of age and older, chew 1 tablet daily. Instruct child to chew tablet thoroughly before swallowing.

Formulation

Supports healthy digestive flora

Supports healthy digestive flora for kids ages 2+

Bottled and tested in the USA

True Potency guarantee

Gluten free

FDA Statement of Identity

Probiotic Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Recommendation: Not for children under 2 years of age due to choking hazard.

Caution: If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Not for use in premature infants. Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Storage

Keep refrigerated to maintain maximum potency.

Keep tightly closed. Keep refrigerated to maintain maximum potency.

Brand IP Statement(s)

Copyright 2024

General Statements

Explore more poducts at naturesway.com LHBN14243.D01 B712006D

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Primadophilus Kids Cherry Flavored by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Primadophilus Kids Cherry Flavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Primadophilus Kids Cherry Flavored by Nature's Way

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Chewable Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

28 mg per serving

Other (inactive) ingredients: Xylitol, Inulin, Hydroxypropyl Cellulose, Stearic Acid, Natural Flavors, Malic Acid, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Primadophilus Kids Cherry Flavored by Nature's Way Drug Interactions

Want to check YOUR meds against Primadophilus Kids Cherry Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus LA-14 182
Bifidobacterium bifidum lactis Bb-02 182

Individual Drug Interactions

The ingredients in Primadophilus Kids Cherry Flavored interact with 182 drugs. Click any drug to see the details.

2 of the 3 ingredients in Primadophilus Kids Cherry Flavored interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus LA-14 Bifidobacterium bifidum lactis Bb-02

Each ingredient & the kinds of drugs it affects

For each ingredient in Primadophilus Kids Cherry Flavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus LA-141 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus LA-14 full monograph & interactions

Bifidobacterium bifidum lactis Bb-021 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium bifidum lactis Bb-02 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Primadophilus Kids Cherry Flavored, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
naturesway.com
Pharmacist Counseling Corner

Primadophilus Kids Cherry Flavored by Nature's Way: Common Questions

Does Primadophilus Kids Cherry Flavored by Nature's Way interact with any medications?
Yes. Based on its ingredients, Primadophilus Kids Cherry Flavored has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Primadophilus Kids Cherry Flavored contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can my child take this probiotic while on an antibiotic?
Not at the same time. Because antibiotics kill bacteria, including the live organisms in this probiotic, taking them together can make the probiotic less effective. Ask your pharmacist how many hours to space them apart — usually it's a few hours, and some sources suggest waiting until after the antibiotic course is done.
What exactly is in the 'Proprietary Probiotic Blend'?
It contains three types of live bacteria: Lactobacillus acidophilus, Lactobacillus plantarum, and Bifidobacterium bifidum. The exact amounts of each aren't disclosed (that's what 'proprietary' means), but all three are listed as active ingredients.
Will this help with my child's irritable bowel syndrome or diarrhea?
Lactobacillus acidophilus is possibly effective for IBS and antibiotic-associated diarrhea, and Bifidobacterium bifidum is possibly effective for IBS — so there's some evidence they may help. But 'possibly' means the science is still developing, and results vary by child. It's worth trying, but talk to your doctor about what to expect.
Are there any side effects my child might experience?
Gastrointestinal side effects like bloating, gas, belly pain, and loose stools can happen, especially at first, but they're uncommon. Very rarely, a rash or itching has been reported, though it's not clear if it came from the probiotic itself. Most kids tolerate it well.
Is this safe for kids with allergies or a weakened immune system?
Kids with weakened immune systems should check with their doctor first, since these are live organisms that could theoretically cause infection in that setting. If your child has food allergies, review the inactive ingredients — this one contains xylitol and natural flavors. There's not enough evidence to say whether it helps or hurts kids with atopic diseases like eczema.
Can I give this while my child is taking other medications?
That depends on the medication. Antibiotics are the main concern (see above), but use the medication checker on this page to look up your child's specific drugs. If you're unsure, ask your pharmacist — they can spot any interactions we've documented.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Primadophilus Kids Cherry Flavored is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Primadophilus Kids Cherry Flavored label
Go deeper

The Full Monographs Behind Primadophilus Kids Cherry Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph →
Sources

Sources & How We Checked

Primadophilus Kids Cherry Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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