Prostate Formula Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Prostate Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Prostate Formula is a dietary supplement by Cooper Complete with 3 active ingredients. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto extract, Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Prostate Formula by Cooper Complete
Ask about any prescription or over-the-counter medication and we check it for interactions with Prostate Formula by Cooper Complete — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Prostate Formula by Cooper Complete
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This formula has three active ingredients chosen for prostate health. Lycopene is a carotenoid (a plant pigment) from tomatoes and tomato products.
Saw palmetto extract comes from the berries of a small palm tree and has been studied for urinary and prostate symptoms. Pygeum is an extract from African plum tree bark, also traditionally used for prostate support.
The capsule also contains inactive ingredients—sunflower lecithin, hypromellose, and candelilla wax—which help hold the formula together.
Does it work?
Strong evidence
The evidence for this formula's ingredients is mixed. Lycopene is possibly effective for prostate cancer but possibly ineffective for bladder cancer and diabetes; the evidence isn't strong enough to rate it for cholesterol, ALS, or exercise-induced asthma.
Saw palmetto is possibly ineffective for benign prostate enlargement (BPH), the condition it's most often used for, though it's possibly effective for a specific surgical procedure (TURP); evidence is insufficient for bronchitis, hair loss, or urinary symptoms. Pygeum is the strongest candidate—it's likely effective for benign prostate enlargement.
For other uses of pygeum (Alzheimer's, malaria, sexual desire, psychosis), the evidence isn't established in the data we hold.
How safe is it?
Well-documented data
All three ingredients are generally well tolerated overall. Lycopene from food is considered safe, and supplement doses are generally well tolerated, though some people report gastrointestinal side effects like diarrhea, nausea, or bloating.
Saw palmetto is mild and reversible in its side effects—mostly digestive upset, headache, or fatigue—though rare cases of heart rhythm changes have been reported. Pygeum appears well tolerated short-term, though long-term safety data are limited; in studies, nausea and abdominal pain occurred at rates similar to placebo.
For pregnancy: saw palmetto safety data advises against it because of possible hormone effects and lack of safety research, and pygeum has no established safe use in pregnancy. The safety data for lycopene supplements in pregnancy aren't complete, so it's best avoided unless your doctor advises otherwise.
For breastfeeding: saw palmetto and pygeum safety data are insufficient, so both should be avoided. Talk with your doctor or pharmacist about whether this product is right for you if you are pregnant or nursing.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before taking this product if you use blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel—lycopene and saw palmetto may increase bleeding risk. Also confirm it's safe if you're on estrogens or hormonal contraceptives, as saw palmetto may reduce their effectiveness.
No other medication interactions are documented for the ingredients we hold data on.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This formula may be worth considering if you're looking for prostate support, particularly for its pygeum content, which has stronger evidence for benign prostate enlargement. However, if you take blood thinners, antiplatelet drugs, estrogens, or hormonal contraceptives, you'll want to check your exact medications with your doctor or pharmacist before starting—the interactions here matter for how well those drugs work or your bleeding risk.
The long-term safety profile of saw palmetto and pygeum together isn't fully established, so discuss this with your healthcare provider to decide if it's the right fit for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Prostate Formula, straight from the product label.
| Brand | Cooper Complete |
|---|---|
| Barcode (UPC) | 816899000171 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 283477 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Prostate Formula by Cooper Complete, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lycopene | 5 mg | -- |
| Saw Palmetto extract | 200 mg | -- |
| Pygeum extract | 100 mg | -- |
Other ingredients: Sunflower Lecithin, Hypromellose, Candelilla Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested usage: As a dietary supplement, men take two (2) capsules daily or as directed by your health care professional.
Formulation
Gluten-free, Non-GMO.
Custom formulation
Precautions
Warning: Not to be taken by women. If you have any health condition or are taking any medication, consult your health professional before use.
Keep out of reach of children.
Tamper Resistant - Do not use if imprinted safety seal under cap is broken or missing.
Storage
For optimal storage conditions, store in a cool, dry place. (59 degrees-77 degrees F/15 degrees-25 degrees C) (35-65% relative humidity)
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Physician formulated Cooper Aerobics Health & Wellness
Formula
Physician formulated for optimal male health
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Prostate Formula by Cooper Complete label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Prostate Formula by Cooper Complete
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Lycopene
Interacts with122 drugs
Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...
Lycopene monograph & interactionsSaw Palmetto extract
Interacts with174 drugs
Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...
Saw Palmetto extract monograph & interactionsPygeum extract
No knowninteractions
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...
Pygeum extract monograph & interactionsOther (inactive) ingredients: Sunflower Lecithin, Hypromellose, Candelilla Wax. These complete the product’s ingredient list but are not active constituents.
Prostate Formula by Cooper Complete Drug Interactions
HelloPharmacist Interaction Report
Cooper Complete Prostate Formula contains three active ingredients, two of which have documented interactions with medications.
The most serious concern is a moderate-risk interaction: lycopene and saw palmetto both may increase bleeding risk when combined with blood thinners or antiplatelet drugs (medications like warfarin, aspirin, or clopidogrel). Lycopene shows antiplatelet activity in lab research, and saw palmetto is reported to prolong bleeding time.
Read the full breakdown — every affected drug type, severity by severity
Saw palmetto carries two additional moderate-severity interactions. It may reduce how well estrogens and hormonal contraceptives work by interfering with their effects in your body — a particular concern if you rely on birth control or hormone therapy for effectiveness.
Pygeum extract, the third ingredient, has no interactions documented in our data. Altogether, these interactions span 174 individual medications.
Use the search tool on this page to check your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Prostate Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Prostate Formula interact with 174 drugs. Click any drug to see the details.
2 of the 3 ingredients in Prostate Formula interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto extract Lycopene
AbciximabReoPro
How Abciximab interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
Saw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Abciximab interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Abrocitinib interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
Saw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Acenocoumarol interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetaminophen, Aspirin interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetaminophen, Aspirin, Caffeine interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetaminophen, Ibuprofen interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetylsalicylic Acid interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Alteplase, Tpa interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
Saw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Anacaulase-bcdb interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Anagrelide interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Anisindione interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
Saw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Antithrombin Iii interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Apixaban interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
Saw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Argatroban interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital, Caffeine interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital, Caffeine, Phenacetin interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Codeine Phosphate interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Dover's Pwd interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
Saw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine, Hydrocodone interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Orphenadrine interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Prostate Formula — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Prostate Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Saw Palmetto extract
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Lycopene
Anticoagulant/Antiplatelet Drugs
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.
Brand information
Manufacturer and brand details for Prostate Formula, from the product label.
Cooper Complete
See all Cooper Complete products- Name
- Cooper Concepts, Inc.
- Street Address
- 12330 Preston Road
- City
- Dallas
- State
- TX
- ZipCode
- 75230
- Phone Number
- 888-393-2221
- Web Address
- coopercomplete.com
Prostate Formula by Cooper Complete: Common Questions
Does Prostate Formula by Cooper Complete interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help with an enlarged prostate?
Can I take this if I'm on a blood thinner?
Are there side effects?
Is this safe in pregnancy or while breastfeeding?
Can I take this with my birth control?
What is lycopene, and why is it in this formula?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Prostate Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lycopene
Interacts with 122 drugsLycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...
Read the full Lycopene monograph → Herb & supplement monographSaw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographPygeum
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...
Read the full Pygeum monograph →Sources & How We Checked
Prostate Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 35 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lycopene 10 references
- Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
- Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
- Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
- O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
- Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
- Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
- Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
- Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
- Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
- Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed
Saw Palmetto 22 references
- Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
- Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
- Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed
Pygeum 3 references
- Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
- Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
- Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC