Major interaction on record — check this product against your medications before combining. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Protector 2000 Ingredients & Drug Interactions

by Ron Teeguarden's Dragon Herbs

Protector 2000 label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Protector 2000 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Protector 2000 is a dietary supplement by Ron Teeguarden's Dragon Herbs with 3 active ingredients. Its ingredients are commonly taken for immune support, general wellness and antioxidant, adjunct interest during cancer care.Based on those ingredients, 1,000 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Goji Berry Extract, Agaricus fruiting body extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Protector 2000 by Ron Teeguarden's Dragon Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Protector 2000 by Ron Teeguarden's Dragon Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Protector 2000 by Ron Teeguarden's Dragon Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Extract Formula” is a proprietary blend — the label gives one combined amount (1,500 mg) without saying how much of each component you get.

Protector 2000 contains 3 active ingredients: agaricus mushroom, cracked shell duanwood reishi spores, and goji berry extract, all in a proprietary blend. The agaricus and goji extracts are concentrates made from the whole fruiting bodies and fruits, respectively — a traditional approach that brings multiple compounds together rather than isolating single ones.

The product also contains inactive ingredients for the capsule and powder form: pullulan (a capsule material), rice powder, bamboo extract powder, and rice extract blend.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune and general health protection.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for what Protector 2000 does isn't well established in the data we hold. Agaricus mushroom has been studied for allergic rhinitis, osteoporosis, cancer, heart disease, and other conditions, but all of those ratings come back as insufficient reliable evidence to rate.

Goji berry has similar limitations — the data rates sunburn, cardiovascular disease, high blood pressure, weight loss, and quality of life as insufficient reliable evidence to rate. We have no effectiveness data on file for the reishi spores component.

The evidence, ingredient by ingredient Agaricus Mushroom Goji

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Agaricus mushroom is generally well tolerated as a food, but long-term safety as a supplement isn't well established. The most common side effects are mild — abdominal discomfort, diarrhea, and nausea — though rare serious reactions including allergic reactions, liver damage, and a lung condition called interstitial lung disease have been reported.

Three cases of severe liver injury were documented in women with cancer who took agaricus supplements alongside chemotherapy. Goji berry is generally safe as a food, but concentrated supplements have less safety data backing them up.

Allergic reactions including swelling of the face and lips, throat tightness, and in rare cases anaphylaxis have been reported. One case of liver inflammation (autoimmune hepatitis) was linked to goji consumption.

Avoid medicinal amounts during pregnancy — traditional use suggests it may affect the uterus — and use caution while breastfeeding since we don't have enough data either way. There is no safety data on file for reishi spores during pregnancy or breastfeeding.

Side effects, ingredient by ingredient Agaricus Mushroom Goji

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Goji, Agaricus Mushroom.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,001 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your own doctor or pharmacist if you take any blood thinners, especially warfarin — goji berry can significantly increase their effect and bleeding risk. Also check if you're on diabetes drugs (agaricus may lower blood sugar further), blood pressure medications (goji may add to the effect), heart rhythm drugs like flecainide, or any medications broken down by your liver through the CYP2D6, CYP2C19, CYP2C9, or CYP3A4 pathways — goji theoretically affects all of those.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Protector 2000 pairs several traditionally used mushroom and berry extracts, but the evidence for their effectiveness isn't established in our data. If you take blood thinners, diabetes medication, blood pressure drugs, or heart rhythm medications, you need to talk with your own doctor or pharmacist before starting — the interactions are real and potentially serious.

Anyone pregnant, breastfeeding, or with a history of liver problems should check with their own healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Protector 2000, straight from the product label.

Brand Ron Teeguarden's Dragon Herbs
Barcode (UPC) 679372001931
Net contents 100 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 316929
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Protector 2000 by Ron Teeguarden's Dragon Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
33
UPC/BARCODE
679372001931
IngredientAmount% DV
Proprietary Extract Formula1500 mg--
Agaricus fruiting body extract0 NP--
Cracked Shell Duanwood Reishi Spores Extract0 NP--
Goji Berry Extract0 NP--

Other ingredients: Pullulan Polysaccharide, Rice, Powder, Bamboo Extract, Powder, Rice extract Blend

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Protector 2000 is an extraordinary combination of three of the most potent health products known to mankind. Potent immune and general health protection.

Pullulan caps - 100% natural, water-soluble polysaccharide produced through a fermentation process; vegetable origin; non-GMO; no starch, preservatives or chemical modifications; gluten free.

Brand IP Statement(s)

Ron Teeguarden's Dragon Herbs Health Deserves Cultivation

FDA Statement of Identity

Dietary Supplement

General Statements

Protector 2000 500 mg each

Suggested/Recommended/Usage/Directions

Directions: Take 3 capsules, 2 times per day or as directed by a healthcare professional.

Formula

Pullulan caps - 100% natural, water-soluble polysaccharide produced through a fermentation process; vegetable origin; non-GMO; no starch, preservatives or chemical modifications; gluten free.

Precautions

Keep out of the reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Protector 2000 by Ron Teeguarden's Dragon Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Protector 2000 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Protector 2000 by Ron Teeguarden's Dragon Herbs

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container33 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Formula

1500 mg per serving

Other (inactive) ingredients: Pullulan Polysaccharide, Rice, Powder, Bamboo Extract, Powder, Rice extract Blend. These complete the product’s ingredient list but are not active constituents.

Interaction report

Protector 2000 by Ron Teeguarden's Dragon Herbs Drug Interactions

Want to check YOUR meds against Protector 2000?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,000Drugs
2 Major 998 Moderate

Ingredients driving the most interactions

Goji Berry Extract 1,000
Agaricus fruiting body extract 86

Individual Drug Interactions

The ingredients in Protector 2000 interact with 1,000 drugs. Click any drug to see the details.

2 of the 3 ingredients in Protector 2000 interact with drugs. Each result below shows which ingredient is responsible. Goji Berry Extract Agaricus fruiting body extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Protector 2000 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Goji Berry Extract8 drug types · 1,000 drugs

Warfarin (Coumadin)

Goji can increase the effects of warfarin and possibly increase the risk of bleeding.
There are at least 5 case reports of increased international normalized ratio (INR) in patients stabilized on warfarin who began drinking goji juice, concentrated goji tea, or goji wine. Goji may inhibit the metabolism of warfarin by cytochrome P450 2C9 (CYP2C9).

Likelihood Probable Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Animal and in vitro research suggest that goji root bark has hypotensive effects. However, goji fruit juice does not appear to reduce systolic or diastolic blood pressure in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, goji berry might inhibit CYP2C19 and reduce metabolism of CYP2C19 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C19 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2C19 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, goji berry might inhibit CYP2C9 and reduce metabolism of CYP2C9 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C9 enzymes. Additionally, multiple case reports suggest that goji berry concentrated tea and juice inhibit the metabolism of warfarin, a CYP2C9 substrate. Concomitant use with goji may decrease metabolism and increase levels of CYP2C9 substrates.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.
In vitro research shows that goji berry juice inhibits CYP2D6 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2D6 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
In vitro research shows that goji berry juice inhibits CYP3A4 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP3A4 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Flecainide (Tambocor)

Theoretically, goji berry might increase the levels and clinical effects of flecainide.
In one case report, a 75-year-old patient stable on flecainide and warfarin presented to the emergency room with fainting and pleomorphic arrhythmia caused by flecainide toxicity. Flecainide toxicity was attributed to drinking 1-2 glasses of concentrated goji tea daily for 2 weeks. Theoretically, goji may have inhibited the cytochrome P450 2D6 (CYP2D6) metabolism of flecainide.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of goji fruit polysaccharides or goji root bark with antidiabetes drugs might have additive effects.
Animal and in vitro research show that goji root bark and fruit polysaccharides might have hypoglycemic effects. However, clinical research has only shown that taking goji fruit polysaccharides with or without antidiabetes drugs modestly reduces postprandial glucose when compared with control, with no reports of hypoglycemia.

Likelihood Possible Evidence B
Goji Berry Extract full monograph & interactions

Agaricus fruiting body extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
In one clinical study in patients with type 2 diabetes who are stabilized on conventional oral hypoglycemic agents, 3 of 29 patients taking an agaricus mushroom extract 500 mg three times daily for 12 weeks reported hypoglycemia, compared to one of 29 patients in the placebo group.

Likelihood Possible Evidence D
Agaricus fruiting body extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Protector 2000, from the product label.

Ron Teeguarden's Dragon Herbs

See all Ron Teeguarden's Dragon Herbs products
Name
Ron Teeguarden's Dragon Herbs
City
Los Angeles
State
CA
ZipCode
90036
Phone Number
(888) 558-6642
Web Address
www.dragonherbs.com
Pharmacist Counseling Corner

Protector 2000 by Ron Teeguarden's Dragon Herbs: Common Questions

Does Protector 2000 by Ron Teeguarden's Dragon Herbs interact with any medications?
Yes. Based on its ingredients, Protector 2000 has a known interaction with 1,000 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Protector 2000 contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
Not safely based on what we know. Agaricus mushroom — avoid it during pregnancy; we don't have enough safety data. Goji berry — the data advises against medicinal amounts in pregnancy because of limited safety information and traditional reports that it may affect the uterus. For the reishi spores, we have no safety data on file. Talk with your own doctor or pharmacist about whether this product is right for you.
What are the side effects?
Most commonly, agaricus mushroom may cause abdominal discomfort, diarrhea, or nausea. Goji berry allergic reactions — swelling of the face, lips, or throat, mouth itching — have been reported, and in rare cases anaphylaxis. Very rarely, agaricus has been linked to liver damage and a lung condition. We have no adverse effect data on file for reishi spores.
Does this actually work?
We don't have evidence showing that it does. Both agaricus and goji have been studied for conditions like heart disease, diabetes, and high blood pressure, but the evidence doesn't come back strong enough to rate. We have no effectiveness data for reishi spores.
Can I breastfeed while taking this?
Goji berry — there isn't enough reliable data to know either way, so caution is advised. For agaricus and reishi spores, we don't have safety information on file for breastfeeding. Talk with your own doctor or pharmacist for personalized guidance.
What is agaricus mushroom supposed to do?
It's been traditionally used and studied for allergic rhinitis, osteoporosis, cancer, heart disease, and other conditions. However, the evidence we hold isn't reliable enough to rate whether it actually works for any of those.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Protector 2000 label
Go deeper

The Full Monographs Behind Protector 2000’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agaricus Mushroom

Interacts with 86 drugs

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not...

Read the full Agaricus Mushroom monograph → Herb & supplement monograph

Goji

Interacts with 1,000 drugs

Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food. While they are popular for eye health, immune supp...

Read the full Goji monograph →
Sources

Sources & How We Checked

Protector 2000's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agaricus Mushroom 5 references
  1. Hsu CH, Liao YL, Lin SC, et al. The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med 2
  2. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol 2006;36:808-10. PubMed
  3. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
  4. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.
  5. Iwai N, Okuda T, Sawada R, et al. Interstitial lung disease associated with Agaricus blazei Murill in a patient with pancreatic ductal adenocarcinoma receiving gemcitabine-based therapy. Case Rep Gastroenterol 2022;16(1):229-234.

See these in context on the Agaricus Mushroom monograph →

Goji 14 references
  1. Huang KC. The Pharmacology of Chinese Herbs. 2nd ed. Boca Raton, FL: CRC Press, LLC 1999.
  2. Lam AY, Elmer GW, Mohutsky MA. Possible interaction between warfarin and Lycium Barbarum. Ann Pharmacother 2001;35:1199-201.
  3. Leung H, Hung A, Hui AC, Chan TY. Warfarin overdose due to the possible effects of Lycium barbarum L. Food Chem Toxicol 2008;46:1860-2. PubMed
  4. Amagase H, Nance DM. A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (goji) juice, GoChi. J Altern Complement Med 2008;14:403-12.
  5. Rivera, C. A., Ferro, C. L., Bursua, A. J., and Gerber, B. S. Probable interaction between Lycium barbarum (goji) and warfarin. Pharmacotherapy 2012;32(3):e50-e53.
  6. Monzon, Ballarin S., Lopez-Matas, M. A., Saenz, Abad D., Perez-Cinto, N., and Carnes, J. Anaphylaxis associated with the ingestion of Goji berries (Lycium barbarum). J.Investig.Allergol.Clin.Immunol. 2011;21(7):567-570.
  7. Franco, M., Monmany, J., Domingo, P., and Turbau, M. [Autoimmune hepatitis triggered by consumption of Goji berries]. Med.Clin.(Barc.) 9-22-2012;139(7):320-321.
  8. Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
  9. Larramendi CH, García-Abujeta JL, Vicario S, García-Endrino A, López-Matas MA, García-Sedeño MD, et al. Goji berries (Lycium barbarum): Risk of allergic reactions in individuals with food allergy. J Investig Allergol Clin Immunol. 2012;22(5):345-50.
  10. Cai H, Liu F, Zuo P, Huang G, Song Z, Wang T, et al. Practical application of antidiabetic efficacy of Lycium barbarum polysaccharide in patients with type 2 diabetes. Med Chem. 2015;11(4):383-90.
  11. Potterat O. Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. Planta Med 2010;76(1):7-19.
  12. Guzmán CE, Guzmán-Moreno CG, Assad-Morell JL, Edgar Francisco Carrizales-Sepúlveda EF. Flecainide toxicity associated with the use of goji berries: a case report. Eur Heart J Case Rep. 2021;5(6):ytab204. PubMed
  13. Liu R, Tam TW, Mao J, et al. In vitro activity of Lycium barbarum (Goji) against major human phase I metabolism enzymes. Complement Integr Med. 2016;13(3):257-265.
  14. Zhang J, Tian L, Xie B. Bleeding due to a probable interaction between warfarin and Gouqizi (Lycium Barbarum L.). Toxicol Rep. 2015;2:1209-1212. PubMed

See these in context on the Goji monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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