Pure Dead Sea Salt Ormus Manna Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pure Dead Sea Salt Ormus Manna against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pure Dead Sea Salt Ormus Manna is a dietary supplement by Ormus Minerals with 2 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 205 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dead Sea Salt. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Pure Dead Sea Salt Ormus Manna by Ormus Minerals
Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Dead Sea Salt Ormus Manna by Ormus Minerals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Pure Dead Sea Salt Ormus Manna by Ormus Minerals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 2 active ingredients: dead sea salt and structured filtered water. The dead sea salt is the active component — it's a source of sodium and other mineral salts from the Dead Sea.
There are no inactive ingredients (fillers or binders) listed.
Does it work?
Couldn't assess
The evidence for dead sea salt's effectiveness depends on what you're using it for. It's rated likely effective for cystic fibrosis and possibly effective for preventing kidney damage from amphotericin B (an antifungal medicine).
For bipolar disorder and congestive heart failure, the evidence we hold is insufficient to rate it either way — we don't know whether it works for those conditions.
How safe is it?
Well-documented data
Sodium is essential in small amounts, but too much is linked to high blood pressure and heart strain. When used orally in normal dietary amounts up to the recommended daily limit, sodium is generally well tolerated.
At high doses, it can worsen cardiovascular disease, high blood pressure, and kidney disease — these are rare but serious risks. Population research has linked high sodium intake to an increased risk of gastric cancer.
Avoid sodium supplements or very high intake without talking to your doctor first. For pregnancy and breastfeeding, sodium is rated likely safe during pregnancy, but the safety data we hold rates it possibly unsafe during lactation — talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before using this product if you take lithium — sodium can alter lithium levels and reduce its effectiveness. Also double-check if you're on any blood pressure medication (antihypertensive), corticosteroids, didanosine, sodium phosphate products, tolvaptan, or other sodium-containing drugs — extra sodium may reduce their effect or raise your sodium level too high.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is mainly a source of dietary sodium. It may help with cystic fibrosis or certain kidney complications from antifungal treatment, but the evidence for other uses isn't clear.
If you take lithium, blood pressure medication, corticosteroids, or any other medication that involves sodium or blood pressure, you need to check with your own doctor or pharmacist before adding this — the sodium content could reduce how well your drugs work or cause your sodium levels to climb too high. Talk it over with them first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pure Dead Sea Salt Ormus Manna, straight from the product label.
| Brand | Ormus Minerals |
|---|---|
| Net contents | 32 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 298244 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pure Dead Sea Salt Ormus Manna by Ormus Minerals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Dead Sea Salt | 0 NP | -- |
| Structured Filtered Water | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Shake bottle. Take 1/2 tsp. to 2 tsp 2X Daily. Recommend mixing with water or juice on an empty stomach as an energy supplement.
Precautions
Precautions: Keep away from children.
Consult with your health provider for use of this product.
Storage
Do not refrigerate. Keep away from direct sunlight. Keep 6' from (EMF). (Electro Magnetic Fields)
General Statements
www.WhatIsOrmus.com
New & Improved
Formulation
100% Natural
No preservatives
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pure Dead Sea Salt Ormus Manna by Ormus Minerals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pure Dead Sea Salt Ormus Manna by Ormus Minerals
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 Teaspoon(s) Dosage formLiquid Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dead Sea Salt
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Dead Sea Salt monograph & interactionsStructured Filtered Water
Pure Dead Sea Salt Ormus Manna by Ormus Minerals Drug Interactions
HelloPharmacist Interaction Report
Pure Dead Sea Salt Ormus Manna by Ormus Minerals contains sodium (from dead sea salt) that interacts with over 200 medications across several drug categories.
The most serious concern is with lithium — high sodium intake can lower lithium levels in your blood and reduce how well it works to control bipolar disorder, while cutting sodium intake can raise lithium levels and cause toxicity.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions also affect blood pressure medications (antihypertensives), corticosteroids, didanosine (an HIV medication), sodium phosphates (used for bowel prep), tolvaptan (a medication that raises sodium levels), and other sodium-containing drugs. In each case, extra dietary sodium from this product may either reduce drug effectiveness or raise your sodium levels too high, depending on the medication.
Altogether, these interactions span 205 individual medications.
We could not check structured filtered water for interactions. Before you start this product, run your exact medications through the interaction checker on this page — especially if you take any blood pressure drug, lithium, corticosteroids, or any medication you know contains sodium.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Pure Dead Sea Salt Ormus Manna?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Pure Dead Sea Salt Ormus Manna interact with 205 drugs. Click any drug to see the details.
1 of the 2 ingredients in Pure Dead Sea Salt Ormus Manna interact with drugs. Each result below shows which ingredient is responsible. Dead Sea Salt
GuanfacineTenex
How Guanfacine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Guanfacine interactionHydralazineApresoline, Apresoline Injection, Dralzine, Hydralazine, Hylazin
How Hydralazine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydralazine interactionHydralazine, HydrochlorothiazideApresazide, Apresoline-Esidrix
How Hydralazine, Hydrochlorothiazide interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydralazine, Hydrochlorothiazide interactionHydralazine, Hydrochlorothiazide, ReserpineSer-Ap-Es, Unipres, Uniserp
How Hydralazine, Hydrochlorothiazide, Reserpine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydralazine, Hydrochlorothiazide, Reserpine interactionHydralazine, ReserpineSerpasil-Apresoline1, Serpasil-Apresoline2
How Hydralazine, Reserpine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydralazine, Reserpine interactionHydrochlorothiazideAquazide, Aquazide H, Esidrix, HCTZ, Hydro, Hydro-D +3 more
How Hydrochlorothiazide interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide interactionHydrochlorothiazide, IrbesartanAvalide
How Hydrochlorothiazide, Irbesartan interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Irbesartan interactionHydrochlorothiazide, LabetalolTrandate HCT
How Hydrochlorothiazide, Labetalol interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Labetalol interactionHydrochlorothiazide, LisinoprilPrinzide, Zestoretic
How Hydrochlorothiazide, Lisinopril interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Lisinopril interactionHydrochlorothiazide, Losartan PotassiumHyzaar
How Hydrochlorothiazide, Losartan Potassium interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Losartan Potassium interactionHydrochlorothiazide, MethyldopaAldoril 15, Aldoril 25, Aldoril D30, Methazide
How Hydrochlorothiazide, Methyldopa interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Methyldopa interactionHydrochlorothiazide, MetoprololLopressor HCT
How Hydrochlorothiazide, Metoprolol interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Metoprolol interactionHydrochlorothiazide, MoexiprilUniretic
How Hydrochlorothiazide, Moexipril interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Moexipril interactionHydrochlorothiazide, PindololViskazide
How Hydrochlorothiazide, Pindolol interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Pindolol interactionHydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Propranolol interactionHydrochlorothiazide, QuinaprilAccuretic
How Hydrochlorothiazide, Quinapril interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Quinapril interactionHydrochlorothiazide, ReserpineHydropres, Serpasil-Esidrix, Serpasil-Esidrix #1, Serpasil-Esidrix #2
How Hydrochlorothiazide, Reserpine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Reserpine interactionHydrochlorothiazide, SpironolactoneAldactazide, Aldactide 25, Aldactide 50, Spirozine
How Hydrochlorothiazide, Spironolactone interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Spironolactone interactionHydrochlorothiazide, TimololTimolide
How Hydrochlorothiazide, Timolol interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Timolol interactionHydrochlorothiazide, TriamtereneDyazide, Maxzide, Maxzide-25, Triamzide, Triazide
How Hydrochlorothiazide, Triamterene interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Triamterene interactionHydrochlorothiazide, ValsartanDiovan HCT
How Hydrochlorothiazide, Valsartan interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydrochlorothiazide, Valsartan interactionHydrocortisoneAlkindi Sprinkle, Alphaderm, Calmurid HC, Carmol HC cream, Cortef, Dioderm +8 more
How Hydrocortisone interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Dead Sea Salt + Hydrocortisone interactionHydroflumethiazideSaluron
How Hydroflumethiazide interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydroflumethiazide interactionHydroflumethiazide, ReserpineSalutensin, Salutensin-Demi
How Hydroflumethiazide, Reserpine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Hydroflumethiazide, Reserpine interactionIloprostAurlumyn, Ventavis
How Iloprost interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Iloprost interactionIndapamideLozide, Lozol
How Indapamide interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Indapamide interactionIrbesartanAprovel, Avapro
How Irbesartan interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Irbesartan interactionIrbesartan, HydrochlorothiazideCoAprovel
How Irbesartan, Hydrochlorothiazide interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Irbesartan, Hydrochlorothiazide interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Isosorbide Dinitrate, Hydralazine interactionIsradipineDynacirc CR
How Isradipine interacts with Pure Dead Sea Salt Ormus Manna — through 1 ingredient. Tap an ingredient for the detail:
Dead Sea SaltAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Dead Sea Salt + Isradipine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Pure Dead Sea Salt Ormus Manna with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Dead Sea Salt
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Pure Dead Sea Salt Ormus Manna, from the product label.
Ormus Minerals
See all Ormus Minerals products- Name
- Ormus Minerals
- Street Address
- P.O. Box 513
- City
- Caldwell
- State
- ID
- ZipCode
- 83606
- Web Address
- www.OrmusMinerals.com
Pure Dead Sea Salt Ormus Manna by Ormus Minerals: Common Questions
Does Pure Dead Sea Salt Ormus Manna by Ormus Minerals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this product safe during pregnancy or breastfeeding?
Does this really work for cystic fibrosis?
Can I take this if I have high blood pressure?
What's the difference between dead sea salt and regular salt?
What are the side effects?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pure Dead Sea Salt Ormus Manna is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pure Dead Sea Salt Ormus Manna’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pure Dead Sea Salt Ormus Manna's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 38 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
- Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
- Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
- Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
- Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
- Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
- D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
- Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
- Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
- Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
- Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
- Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
- Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
- Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
- O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
- Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
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