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Dietary supplement

PureBerry+Purse Ingredients & Drug Interactions

by Advanced Nutrition by Zahler

PureBerry+Purse label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PureBerry+Purse against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PureBerry+Purse is a dietary supplement by Advanced Nutrition by Zahler with 2 active ingredients. Its ingredients are commonly taken for pregnancy and labor support, menstrual cramps, digestive upset and diarrhea.Based on those ingredients, 380 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shepherd's Purse Aerial Parts extract, Red Raspberry Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against PureBerry+Purse by Advanced Nutrition by Zahler

Ask about any prescription or over-the-counter medication and we check it for interactions with PureBerry+Purse by Advanced Nutrition by Zahler — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of PureBerry+Purse by Advanced Nutrition by Zahler

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

PureBerry+Purse is a liquid with two active ingredients. Red Raspberry Leaf Extract and Shepherd's Purse Aerial Parts Extract are the working components.

The product also contains inactive ingredients—glycerin, purified water, natural mixed berry flavor, and peppermint essential oil—which serve as the liquid base and flavoring.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: promote uterine health and manage heavy menstrual bleeding.
  • We looked for evidence on: Dysmenorrhea, Menorrhagia, Postpartum complications, menstrual cycle regulation, midcycle spotting.
  • The closest evidence on file: Shepherd's Purse is rated "Insufficient Reliable Evidence To Rate" for Postpartum complications (Natural Medicines).
  • Also on file: Shepherd's Purse is rated "Insufficient Reliable Evidence To Rate" for Menorrhagia.
  • Also on file: Red Raspberry is rated "Insufficient Reliable Evidence To Rate" for Dysmenorrhea, Menorrhagia.

The evidence we hold doesn't establish effectiveness for either ingredient. Red Raspberry Leaf has insufficient reliable evidence for aging skin, cardiovascular disease, respiratory tract infections, congestive heart failure, and diabetes.

Shepherd's Purse Aerial Parts has insufficient reliable evidence for postpartum complications and heavy menstrual bleeding (menorrhagia). This doesn't mean the product doesn't work—just that the data we have isn't robust enough to call it proven.

The evidence, ingredient by ingredient Red Raspberry Shepherd's Purse

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Red Raspberry Leaf is generally well tolerated by most adults, though safety evidence is limited. The most common side effects are diarrhea, gastrointestinal upset, and epigastric pain (upper abdominal discomfort), though these are uncommon at typical doses.

One case of occupational asthma from inhaling red raspberry powder was reported. Pregnancy safety data for red raspberry leaf is mixed—the data we hold shows conflicting ratings, so talk with your provider before using it in pregnancy.

We don't hold enough information on safety while breastfeeding. Shepherd's Purse is well tolerated in small amounts, short-term, but human safety data are limited.

Adverse effects traditionally linked to it include sedation, high or low blood pressure, thyroid problems, abnormal menstruation, and heart palpitations. The safety data we have advises against use during pregnancy (it may stimulate the uterus) and while breastfeeding (insufficient data).

Side effects, ingredient by ingredient Red Raspberry Shepherd's Purse

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Shepherd's Purse, Red Raspberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 380 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with us before taking this if you use blood thinners or antiplatelet drugs (like warfarin or aspirin), insulin, sedating medications (like benzodiazepines or sleep aids), or thyroid hormone replacement. These are the Moderate interactions we've documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product isn't established to work for its named uses. If you take blood thinners, insulin, sedating medications, or thyroid hormone replacement, you need to check with us before starting it.

Pregnant or breastfeeding? Talk to your provider or pharmacist—this one's not straightforward.

It's generally well tolerated at normal doses, but the evidence on what it actually does is thin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PureBerry+Purse, straight from the product label.

Brand Advanced Nutrition by Zahler
Barcode (UPC) 848998081799
Net contents 8 Fluid Ounce(s); 236.6 mL
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 301107
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PureBerry+Purse by Advanced Nutrition by Zahler, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.5 mL
Maximum serving Sizes:
7.5 mL
Servings per container
32
UPC/BARCODE
848998081799
IngredientAmount% DV
Calories25 Calorie(s)--
Total Carbohydrates5 Gram(s)2%
Red Raspberry Leaf Extract625 mg--
Shepherd's Purse Aerial Parts extract290 mg--

Other ingredients: Glycerin, Water, Purified, Natural Mixed Berry Flavor, Peppermint Essential Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Red Raspberry Leaf & Shepherds Purse

Kosher Pareve D OU (Kosher) Under the strict supervision of Rabbi SH. Stern & The Orthodox Union

Women's Health

Formulation

PureBerry + Purse contains herbs traditionally used to promote uterine health and to address normal but heavy menstrual bleeding. Use this product to help manage heavy yet normal menstrual flow as well as midcycle spotting.

Non-GMO Gluten free Dairy free Soy free

Vegetarian Friendly

Alcohol free liquid Red Raspberry Leaf & Shepherds Purse

Strengthens uterine tissue & muscles + Menstrual Support

Herbal

GMP

General Statements

You may need additional supplements to support a healthy diet; consult your nutritionist for a formula that is right for you or contact us at: 877-ASK-ZAHLER (877-275-9245) or [email protected].

Servings per container: About 32

Precautions

Keep out of reach of children

Do not use if safety seal is damaged or missing.

If pregnant, nursing or on medication, consult with your healthcare practitioner.

Warning: This product should not be taken during pregnancy.

FDA Disclaimer Statement

These statements have not been evaluated by the Food ad Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Kosher Pareve D OU (Kosher)

Manufactured in the USA

Storage

Store tightly closed in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Advanced Nutrition by Zahler Feel Better, Everyday

PureBerry + Purse is a trademark of Advanced Nutrition by Zaher.

Suggested/Recommended/Usage/Directions

Directions: Mix 1.5 teaspoons with 2 ounces of water or juice twice daily or as directed by a healthcare practitioner. Shake well before use.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PureBerry+Purse by Advanced Nutrition by Zahler label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PureBerry+Purse label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PureBerry+Purse by Advanced Nutrition by Zahler

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size7.5 mL Dosage formLiquid Servings per container32 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Red Raspberry Leaf Extract

Interacts with
135 drugs
625 mg per serving

Red raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scientific eviden...

Red Raspberry Leaf Extract monograph & interactions

Shepherd's Purse Aerial Parts extract

Interacts with
264 drugs
290 mg per serving

Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is ver...

Shepherd's Purse Aerial Parts extract monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Purified, Natural Mixed Berry Flavor, Peppermint Essential Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

PureBerry+Purse by Advanced Nutrition by Zahler Drug Interactions

Want to check YOUR meds against PureBerry+Purse?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
380Drugs
380 Moderate

Ingredients driving the most interactions

Shepherd's Purse Aerial Parts extract 264
Red Raspberry Leaf Extract 135

Individual Drug Interactions

The ingredients in PureBerry+Purse interact with 380 drugs. Click any drug to see the details.

2 of the 2 ingredients in PureBerry+Purse interact with drugs. Each result below shows which ingredient is responsible. Shepherd's Purse Aerial Parts extract Red Raspberry Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in PureBerry+Purse with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Shepherd's Purse Aerial Parts extract2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, concomitant use may interfere with thyroid dysfunction therapy.

Likelihood Possible Evidence D
Shepherd's Purse Aerial Parts extract full monograph & interactions

Red Raspberry Leaf Extract2 drug types · 135 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that red raspberry leaf extract has antiplatelet activity and enhances the in vitro effects of the antiplatelet medication cangrelor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Insulin

Red raspberry leaf might reduce glucose levels in patients being treated with insulin.
In one case report, a 38-year-old patient with gestational diabetes, whose blood glucose was being controlled with medical nutrition therapy and insulin, developed hypoglycemia after consuming two servings of raspberry leaf tea daily for 3 days beginning at 32 weeks' gestation. The patient required an insulin dose reduction. The hypoglycemia was considered to be probably related to use of red raspberry leaf tea.

Likelihood Possible Evidence D
Red Raspberry Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PureBerry+Purse, from the product label.

Advanced Nutrition by Zahler

See all Advanced Nutrition by Zahler products
Name
Advanced Nutrition by Zahler
City
Brooklyn
State
NY
ZipCode
11230
Phone Number
877-275-9245
Web Address
www.zahlers.com
Pharmacist Counseling Corner

PureBerry+Purse by Advanced Nutrition by Zahler: Common Questions

Does PureBerry+Purse by Advanced Nutrition by Zahler interact with any medications?
Yes. Based on its ingredients, PureBerry+Purse has a known interaction with 380 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PureBerry+Purse contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
The safety data we have is mixed for red raspberry leaf—some sources call it likely safe, others possibly safe, and still others likely unsafe, so we can't give you a clear answer. Shepherd's Purse should be avoided in pregnancy because it may stimulate the uterus. Talk with your provider or pharmacist for advice tailored to your situation.
Can I take this while breastfeeding?
We don't hold enough information to know whether red raspberry leaf is safe while breastfeeding. Shepherd's Purse should be avoided because we don't have enough safety data. Check with your pharmacist or doctor before starting it.
What does red raspberry leaf do?
We don't have established evidence that it works for aging skin, heart disease, respiratory infections, heart failure, or diabetes. The data we hold on its effectiveness just isn't solid enough to confirm a benefit.
What does shepherd's purse do?
We don't have established evidence that it works for postpartum complications or heavy menstrual bleeding. The research data we hold doesn't support those uses.
Will this product lower my blood sugar if I'm on insulin?
Red raspberry leaf might reduce blood sugar levels in people taking insulin. One case report documented low blood sugar after someone consumed raspberry leaf tea daily. If you're on insulin, check with your pharmacist before starting this product.
What are the most common side effects?
For red raspberry leaf, diarrhea, gastrointestinal upset, and upper abdominal pain are the most commonly reported—though they don't happen often at typical doses. Shepherd's purse is generally well tolerated in short-term use, though safety data are limited overall.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PureBerry+Purse is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PureBerry+Purse label
Go deeper

The Full Monographs Behind PureBerry+Purse’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Red Raspberry

Interacts with 135 drugs

Red raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scientific evidence for these uses is limited. It is gene...

Read the full Red Raspberry monograph → Herb & supplement monograph

Shepherd's Purse

Interacts with 264 drugs

Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is very limited. Because it may affect blood c...

Read the full Shepherd's Purse monograph →
Sources

Sources & How We Checked

PureBerry+Purse's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Red Raspberry 8 references
  1. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  2. Parsons M, Simpson M, Ponton T. Raspberry leaf and its effects on labour: safety and efficacy. Aust Coll Midwives Inc J 1999;12:20-5.
  3. Simpson M, Parsons M, Greenwood J, Wade K. Raspberry leaf in pregnancy: its safety and efficacy in labor. J Midwifery Womens Health 2001;46:51-9.. PubMed
  4. Mullen W, McGinn J, Lean ME, et al. Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties. J Agric Food Chem 2002;50:5191-6.. PubMed
  5. Sherson, D., Andersen, B., Hansen, I., and Kjoller, H. Occupational asthma due to freeze-dried raspberry. Ann Allergy Asthma Immunol. 2003;90(6):660-663. PubMed
  6. Cheang KI, Nguyen TT, Karjane NW, Salley KE. Raspberry Leaf and Hypoglycemia in Gestational Diabetes Mellitus. Obstet Gynecol. 2016;128(6):1421-4. PubMed
  7. Dudzinska D, Bednarska K, Boncler M, Luzak B, Watala C. The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils. Platelets. 2016;27(5):433-9.
  8. Henrotin Y, Cozannet RL, Fança-Berthon P, et al. Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial. BMC Musculoskelet Disord 2022;23(1):650. PubMed

See these in context on the Red Raspberry monograph →

Shepherd's Purse 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Naafe M, Kariman N, Keshavarz Z, et al. Effect of hydroalcoholic extracts of Capsella bursa-pastoris on heavy menstrual bleeding: A randomized clinical trial. J Altern Complement Med. 2018;24(7):694-700. PubMed
  4. Ghalandari S, Kariman N, Sheikhan Z, et al. Effect of hydroalcoholic extract of Capsella bursa pastoris on early postpartum hemorrhage: A clinical trial study. J Altern Complement Med. 2017;23(10):794-799.

See these in context on the Shepherd's Purse monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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