Pycnogenol 25 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pycnogenol 25 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pycnogenol 25 mg is a dietary supplement by Natural Factors with 1 active ingredient. Its ingredients are commonly taken for circulation and vein health, antioxidant support, skin health and aging.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pycnogenol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Pycnogenol 25 mg by Natural Factors
Ask about any prescription or over-the-counter medication and we check it for interactions with Pycnogenol 25 mg by Natural Factors — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Pycnogenol 25 mg by Natural Factors
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Pycnogenol” is listed as a grouped ingredient — the label gives one combined amount (25 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pycnogenol 25 mg, straight from the product label.
| Brand | Natural Factors |
|---|---|
| Barcode (UPC) | 068958020907 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 23, 2017 |
| DSLD ID | 75398 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Seniors/Mature (>50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pycnogenol 25 mg by Natural Factors, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Procyanidins | 15 mg | -- |
| Pycnogenol | 25 mg | -- |
Other ingredients: Microcrystalline Cellulose, Vegetarian Capsule, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
isura Non-GMO - Mass spec Documentation - Lab tested
Purity & potency guaranteed
Suggested/Recommended/Usage/Directions
Suggested Usage: 1 capsule 1–2 times per day or as directed by a health professional.
Precautions
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.
Keep out of the reach of children.
Sealed for your protection. Do not use if seal is broken.
General Statements
Pycnogenol French maritime pine bark extract is extracted from the bark of pine trees (Pinus pinaster) grown exclusively in Les Landes de Gascogne forest in southwest France near the famous Bordeaux region.
May help provide support for healthy joint function and maintenance. May support natural inflammation transition from acute to resolution state. Helps reduce (climacteric) symptoms associated with peri-menopause including hot flashes, restlessness (difficulty falling asleep), and poor mental concentration and focus.
Provides antioxidants for the maintenance of good health.
Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada
Product of Canada Recyclable container and label.
Healthy aging
Formulation
The forest is an unspoiled and natural plantation with no pesticides and no herbicides.
Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.
Suitable for vegetarians/vegans.
Formula
Helps support cognitive health in an aging population (>60 years of age).
French maritime pine bark extract
Storage
For freshness, store in a cool, dry place.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Pycnogenol is a registered trademark of Horphag Research Management SA. Use of this product is protected by one or more of U.S. patents and other international patents.
General
R7
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pycnogenol 25 mg by Natural Factors label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pycnogenol 25 mg by Natural Factors
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.
Pycnogenol
Interacts with327 drugs
Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research...
Pycnogenol monograph & interactions- › Procyanidins
Other (inactive) ingredients: Microcrystalline Cellulose, Vegetarian Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Pycnogenol 25 mg by Natural Factors Drug Interactions
Pycnogenol 25 mg contains a single active ingredient, and it has known interactions with 327 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Pycnogenol 25 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Pycnogenol 25 mg interact with 327 drugs. Click any drug to see the details.
1 of the 1 ingredient in Pycnogenol 25 mg interact with drugs. Each result below shows which ingredient is responsible. Pycnogenol
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pycnogenol + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pycnogenol + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pycnogenol + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Alemtuzumab interactionAlogliptinNesina
How Alogliptin interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pycnogenol + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pycnogenol + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pycnogenol + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pycnogenol + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with Pycnogenol 25 mg — through 1 ingredient. Tap an ingredient for the detail:
PycnogenolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pycnogenol + Anisindione interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Pycnogenol 25 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Pycnogenol
Anticoagulant/Antiplatelet Drugs
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Clinical research suggests that maritime pine bark extract inhibits platelet aggregation. However, the clinical significance of this effect is unclear.
Antidiabetes Drugs
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
One clinical study shows that maritime pine bark extract decreases blood sugar in patients with diabetes being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Immunosuppressants
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
In vitro and animal research suggests that maritime pine bark extract has immunostimulant activity. This effect has not been reported in humans.
Brand information
Manufacturer and brand details for Pycnogenol 25 mg, from the product label.
Pycnogenol 25 mg by Natural Factors: Common Questions
Does Pycnogenol 25 mg by Natural Factors interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pycnogenol 25 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pycnogenol 25 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pycnogenol 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 14 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Maritime Pine 14 references
- Rice-Evans CA, Packer L, eds. Flavonoids in Health and Disease. Manhattan, NY: Marcel Dekker, Inc., 1998.
- Liu FJ, Zhang YX, Lau BH. Pycnogenol enhances immune and haemopoietic functions in senescence-accelerated mice. Cell Mol Life Sci 1998;54:1168-72. PubMed
- Putter M, Grotemeyer KH, Wurthwein G, et al. Inhibition of smoking-induced platelet aggregation by aspirin and pycnogenol. Thromb Res 1999;95:155-61. PubMed
- Kohama T, Inoue M. Pycnogenol alleviates pain associated with pregnancy. Phytother Res 2006;20:232-4.
- Liu X, Zhou HJ, Rohdewald P. French maritime pine bark extract pycnogenol dose-dependently lowers glucose in type 2 diabetic patients (letter). Diabetes Care 2004;27:839. PubMed
- Liu X, Wei J, Tan F, et al. Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II. Life Sci 2004;75:2505-13. PubMed
- Wilson D, Evans M, Guthrie N et al. A randomized, double-blind, placebo-controlled exploratory study to evaluate the potential of pycnogenol for improving allergic rhinitis symptoms. Phytother Res 2010;24:1115-9.
- Araghi-Niknam, M., Hosseini, S., Larson, D., Rohdewald, P., and Watson, R. R. Pine bark extract reduces platelet aggregation. Integr.Med. 3-21-2000;2(2):73-77. PubMed
- Trebaticka, J., Kopasova, S., Hradecna, Z., Cinovsky, K., Skodacek, I., Suba, J., Muchova, J., Zitnanova, I., Waczulikova, I., Rohdewald, P., and Durackova, Z. Treatment of ADHD with French maritime pine bark extract, Pycnogenol. Eur.Child Adolesc.Psychi PubMed
- Suzuki, N., Uebaba, K., Kohama, T., Moniwa, N., Kanayama, N., and Koike, K. French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study
- Cisar, P., Jany, R., Waczulikova, I., Sumegova, K., Muchova, J., Vojtassak, J., Durackova, Z., Lisy, M., and Rohdewald, P. Effect of pine bark extract (Pycnogenol) on symptoms of knee osteoarthritis. Phytother.Res. 2008;22(8):1087-1092.
- Enseleit, F., Sudano, I., Periat, D., Winnik, S., Wolfrum, M., Flammer, A. J., Frohlich, G. M., Kaiser, P., Hirt, A., Haile, S. R., Krasniqi, N., Matter, C. M., Uhlenhut, K., Hogger, P., Neidhart, M., Luscher, T. F., Ruschitzka, F., and Noll, G. Effects
- Schoonees, A., Visser, J., Musekiwa, A., and Volmink, J. Pycnogenol(R) (extract of French maritime pine bark) for the treatment of chronic disorders. Cochrane.Database.Syst.Rev. 2012;4:CD008294.
- Wang S, Tan D Zhao Y et al. The effect of pycnogenol on the microcirculation, platelet function and ischemic myocardium in patients with coronary artery diseases. Eur Bull Drug Res 1999;7:19-25.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC