No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pygeum Bark 4500 mg Ingredients & Drug Interactions

by NusaPure

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum Bark 4500 mg is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum Bark 4500 mg by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pygeum bark extract at 4500 mg per capsule. Pygeum is a plant extract traditionally used for prostate health.

The capsule also contains inactive ingredients (cellulose, silica, magnesium stearate powder, and rice flour powder) that serve as binders and fillers.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: prostate health and urinary function.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Urinary symptoms, Prostate symptoms, Male urinary health.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum bark extract is likely effective for benign prostatic hyperplasia, or BPH — the enlargement of the prostate gland that can cause urinary symptoms in older men. For other uses listed in our data — Alzheimer disease, malaria, sexual desire, and psychosis — the evidence isn't established well enough to rate it.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum is generally well tolerated in short-term use, but quality and long-term safety data are limited. In clinical trials, some participants reported nausea and abdominal pain, though the rate was similar to placebo.

The safety data advises against use in pregnancy and breastfeeding, since this product is formulated for men's prostate health and there isn't enough data on safety for pregnant or nursing people.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, run your exact medications through the checker on this page before you start, or ask your pharmacist — it's always the safest move.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're a man with BPH symptoms looking for a plant-based option, pygeum bark extract is likely to help. Anyone concerned about long-term use should know the data here are sparse.

Talk with your pharmacist about whether this fits your health goals and how long you plan to take it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum Bark 4500 mg, straight from the product label.

Brand NusaPure
Barcode (UPC) X001WME1UB
Net contents 180 Veg Cap(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 307384
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum Bark 4500 mg by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
180
UPC/BARCODE
X001WME1UB
IngredientAmount% DV
Pygeum Bark Extract450 mg--

Other ingredients: Cellulose, Silica, Magnesium Stearate, Powder, Rice Flour, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one (1) capsules daily, preferably with a meal.

Precautions

Warning: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Do not eat freshness packet. Do not use if safety seal is damaged or missing. Discontinue use and consult your doctor if any adverse reactions occur.

Allergen information: Contains no artificial coloring, artificial flavors, yeast, corn starch, milk, or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, egg, wheat, fish, shellfish or tree nut ingredients. Produced in a facility that processes other ingredients containing these allergens.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium quality Assembled in USA GMO free Made with Non-GMO ingredients Gluten free FDA Registered Facility

Manufactured in a cGMP inspected facility

Formulation

GMO free Made with Non-GMO ingredients Gluten free FDA Registered Facility

Assembled in USA Tested Supports prostate & urinary health Supports sexual health Max strength

Allergen information: Contains no artificial coloring, artificial flavors, yeast, corn starch, milk, or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, egg, wheat, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

FDA Statement of Identity

Dietary Supplement

See for yourself

Pygeum Bark 4500 mg by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum Bark 4500 mg by NusaPure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Pygeum Bark Extract

No known
interactions
450 mg per serving Form: Pygeum africanum Bark Extract

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum Bark Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Silica, Magnesium Stearate, Powder, Rice Flour, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pygeum Bark 4500 mg by NusaPure Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum Bark 4500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum Bark 4500 mg, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central, LLC
Street Address
4700 Millenia Boulevard, Suite 175 PMB 92909
City
Orlando
State
FL
ZipCode
32839
Pharmacist Counseling Corner

Pygeum Bark 4500 mg by NusaPure: Common Questions

Does Pygeum Bark 4500 mg by NusaPure interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum Bark 4500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum Bark 4500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pygeum bark extract, and what's it used for?
Pygeum is an extract from the bark of an African tree. It's well established for helping with benign prostatic hyperplasia — the enlarged prostate that causes trouble urinating in older men.
Will this help with my sexual function or desire?
The evidence for pygeum on sexual desire isn't established enough to rate it yet. If that's your main concern, talk with your pharmacist about what the science supports.
Is this safe to take long-term?
Pygeum is generally well tolerated in the short term, but we don't have enough long-term safety data to say how it holds up over months or years. Discuss your timeline with your pharmacist.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against it. This product is formulated for men's prostate health, and there isn't enough safety information for pregnancy or breastfeeding.
What side effects did people report in trials?
Some participants reported nausea and abdominal pain, but the rate was about the same as placebo — so they're not common.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum Bark 4500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum Bark 4500 mg label
Go deeper

The Full Monographs Behind Pygeum Bark 4500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum Bark 4500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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