Pygeum Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pygeum against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pygeum is a dietary supplement by NewtonEverett with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Pygeum by NewtonEverett
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: pygeum, an extract from the African cherry tree traditionally used for men's prostate health. The softgel itself is filled with pumpkin seed oil and includes gelatin, vegetable glycerin, soy lecithin, beeswax, and caramel color as inactive ingredients.
Does it work?
Strong evidence
Pygeum is rated likely effective for benign prostatic hyperplasia — that's enlarged prostate that causes trouble with urination. For other conditions listed on the label (Alzheimer disease, malaria, sexual desire, and psychosis), the evidence is insufficient to rate it one way or the other, so we can't say whether it works for those purposes.
How safe is it?
Well-documented data
Pygeum is generally well tolerated in short-term use, though quality and long-term safety data are limited. In clinical trials, some people reported nausea and abdominal pain, but these rates matched placebo — meaning they occurred at similar rates in the control group.
Because it's used for men's prostate health and safety in pregnancy and breastfeeding hasn't been established, it should be avoided by pregnant women and those breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for pygeum. Run your specific medications through the checker on this page to be certain, but we hold no interaction monograph for this ingredient.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you're a man dealing with prostate symptoms, pygeum may be worth discussing with your doctor — the evidence supports it for benign prostatic hyperplasia. If you're pregnant or breastfeeding, skip it.
And if you're on any regular medications, check with your pharmacist before you start, even though documented interactions aren't on file.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pygeum, straight from the product label.
| Brand | NewtonEverett |
|---|---|
| Barcode (UPC) | 689076031479 |
| Net contents | 120 Softgel(s); 100 mg |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2014 |
| DSLD ID | 34789 |
| Product type | Botanical With Nutrients |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult Male (18-50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pygeum by NewtonEverett, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pygeum | 100 mg | -- |
Other ingredients: Pumpkin seed Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, yellow Beeswax, natural Caramel color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Pure - Potent - Bioavailable We are driven to deliver highly potent, ultra-pure nutritional products with uncompromised quality. Our premium-grade liquid softgels are designed to provide an ideal delivery vehicle for maximum absorption and enhanced bioavailability.
Not suitable for vegetarians.
Made in USA
FDA Statement of Identity
dietary supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take one (1) softgel twice daily, preferably with a meal.
Precautions
If you are taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Not intended for use by persons under the age of 18.KEEP OUT OF REACH OF CHILDREN.
Warning: This product is intended for use by men and is not intended for use by women.
Storage
Store at room temperature.
Formulation
No artificial flavor or sweetener, preservatives, sugar, starch, milk, lactose, gluten, wheat, yeast or fish. Sodium free.
Seals/Symbols
newtoneverett(R)
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pygeum by NewtonEverett label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pygeum by NewtonEverett
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.
Pygeum
No knowninteractions
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...
Pygeum monograph & interactionsOther (inactive) ingredients: Pumpkin seed Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Yellow Beeswax, Natural Caramel color. These complete the product’s ingredient list but are not active constituents.
Pygeum by NewtonEverett Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Pygeum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Pygeum, from the product label.
NewtonEverett
See all NewtonEverett products- Name
- Newton-Everett Biotech
- Web Address
- www.newton-everett.com
Pygeum by NewtonEverett: Common Questions
Does Pygeum by NewtonEverett interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is pygeum used for?
What side effects might I notice?
Can I take this if I'm pregnant or breastfeeding?
How many active ingredients are in this softgel?
Is this safe to use long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pygeum is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pygeum’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pygeum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pygeum 3 references
- Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
- Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
- Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC