Qing Hao Alcohol Free Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Qing Hao Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Qing Hao Alcohol Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for malaria (traditional), fever, inflammation.Based on those ingredients, 892 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Artemisia annua Herb Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Qing Hao Alcohol Free by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Qing Hao Alcohol Free by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Qing Hao Alcohol Free by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: Artemisia annua herb extract, dry, which our data links to the Sweet Annie monograph. It is the herb extract the product is built around, and the research on it covers allergic rhinitis (hay fever), malaria, nonalcoholic fatty liver disease, and osteoarthritis.
The remaining listed ingredients are inactive: glycerin and water. These are not active ingredients, and the product's full formulation beyond what is listed here is not something our data covers.
Does it work?
Moderate evidence
For allergic rhinitis (hay fever), the evidence is rated Possibly Effective. For nonalcoholic fatty liver disease, malaria, and osteoarthritis, the rating is Insufficient Reliable Evidence To Rate, which means the evidence for those uses is not established in the data we hold.
These ratings describe the research on Artemisia annua, and they do not guarantee results from this specific liquid.
How safe is it?
Well-documented data
Sweet Annie is generally well tolerated, with nausea and vomiting as the most common side effects. Serious liver harm (hepatotoxicity) is listed as a rare side effect.
In one reported case, a 52-year-old taking artemisinin developed hepatitis, and symptoms resolved within two weeks of stopping, though it is not certain the supplement caused the liver disease. A mild allergic reaction with rash and cough has also been reported, and some people allergic to Sweet Annie have reported numbness of the tongue and throat itching with low sublingual doses.
Our safety notes say it is generally used short-term, that quality and dose vary widely, and that it should not replace proven treatments. The notes advise avoiding it during pregnancy because of possible harm to the developing baby, and say there is not enough safety information to use it while breastfeeding, so avoiding it is advised there as well.
Meds to double-check
Moderate interaction found
Double-check with your own doctor or pharmacist before taking this product if you use hepatotoxic drugs (medicines that can harm the liver), CYP3A4 substrates, or CYP2B6 substrates. Each of these interaction types is rated Moderate, and no interaction is rated more seriously for this product.
Your prescriber or pharmacist can review your exact medications.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This product may be of interest to people looking into Sweet Annie for allergic rhinitis, where the evidence is rated Possibly Effective. People who take medications processed by the liver, or who have liver concerns, should be especially careful, given the documented interactions and liver effects.
If you are pregnant or breastfeeding, our safety notes advise avoiding it, so please talk it over with your own doctor or pharmacist before deciding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Qing Hao Alcohol Free, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7439500661672 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 326907 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Qing Hao Alcohol Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Artemisia annua Herb Extract, Dry | 1156 mg | -- |
Other ingredients: Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
No alcohol (ethyl), artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Artemisia annua
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA
General Statements
Organic raw material.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Qing Hao Alcohol Free by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Qing Hao Alcohol Free by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Artemisia annua Herb Extract, Dry
Interacts with892 drugs
Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studie...
Artemisia annua Herb Extract, Dry monograph & interactionsOther (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Qing Hao Alcohol Free by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Herbal Terra's Qing Hao Alcohol Free interacts with a number of medications, and its single ingredient, Artemisia annua herb extract (also called Sweet Annie), is the reason.
Its most serious documented interaction is rated Moderate, with hepatotoxic drugs (medicines that can harm the liver). Because Sweet Annie can adversely affect the liver, taking it alongside these drugs may add to liver effects.
Read the full breakdown — every affected drug type, severity by severity
Sweet Annie may also change how your body processes drugs broken down by two liver enzymes, CYP3A4 and CYP2B6 (cytochrome P450 enzymes). Both are rated Moderate.
Lab research suggests its artemisinin content can speed these enzymes up, while the extract appears to slow them down, so the overall effect on any given drug is hard to predict and could make a medication work more or less strongly than intended.
Altogether, these interactions span 893 individual medications.
To see whether a specific medication is affected, use the search tool on this page to check your exact drugs, and talk with your own doctor or pharmacist before combining them.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Qing Hao Alcohol Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Qing Hao Alcohol Free interact with 892 drugs. Click any drug to see the details.
1 of the 1 ingredient in Qing Hao Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Artemisia annua Herb Extract, Dry
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Beclomethasone Dipropionate interactionBedaquilineSirturo
How Bedaquiline interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Bedaquiline interactionBelinostatBeleodaq
How Belinostat interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Belinostat interactionBelladona Extract, PhenobarbitalChardonna-2
How Belladona Extract, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
Read the full Artemisia Annua Herb Extract, Dry + Belladona Extract, Phenobarbital interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna Alkaloids, PhenobarbitalBarbidonna, Donnatal
How Belladonna Alkaloids, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna Alkaloids, Phenobarbital interactionBelladonna Extract, PhenobarbitalBelap
How Belladonna Extract, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna Extract, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, Ergotamine Tartrate, Phenobarbital
How Belladonna, Ergotamine Tartrate, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 2b6 (cyp2b6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Ergotamine, PhenobarbitalBellergal-S
How Belladonna, Ergotamine, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna, Ergotamine, Phenobarbital interactionBelladonna, PhenobarbitalBellophen, Susano
How Belladonna, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
Read the full Artemisia Annua Herb Extract, Dry + Belladonna, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBellafoline, PhenobarbitalBelladenal, Belladenal-S
How Bellafoline, Phenobarbital interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
Read the full Artemisia Annua Herb Extract, Dry + Bellafoline, Phenobarbital interactionBelumosudil MesylateRezurock
How Belumosudil Mesylate interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Belumosudil Mesylate interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Bendamustine Hydrochloride interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Benzhydrocodone, Acetaminophen interactionBepridilVascor
How Bepridil interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Bepridil interactionBexaroteneTargretin
How Bexarotene interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Bexarotene interactionBictegravir, Emtricitabine, Tenofovir AlafenamideBiktarvy
How Bictegravir, Emtricitabine, Tenofovir Alafenamide interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Bictegravir, Emtricitabine, Tenofovir Alafenamide interactionBimekizumab-bkzxBimzelx
How Bimekizumab-bkzx interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Bimekizumab-bkzx interactionBinimetinibMektovi
How Binimetinib interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Binimetinib interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBoceprevirVictrelis
How Boceprevir interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Herb Extract, Dry + Boceprevir interactionBortezomibVelcade
How Bortezomib interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Bortezomib interactionBosentanTracleer
How Bosentan interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Bosentan interactionBosutinibBosulif
How Bosutinib interacts with Qing Hao Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Herb Extract, DryHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Herb Extract, Dry + Bosutinib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Qing Hao Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Artemisia annua Herb Extract, Dry
Cytochrome P450 2B6 (Cyp2B6) Substrates
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP2B6, possibly increasing CYP2B6 activity by 1.6-fold. However, Sweet Annie extract seems to inhibit the activity of CYP2B6 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP2B6 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP3A4, possibly increasing CYP3A4 activity by 1.9-fold. However, Sweet Annie extract seems to inhibit the activity of CYP3A4 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP3A4 substrates.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
There is some concern that Sweet Annie can adversely affect the liver.
Brand information
Manufacturer and brand details for Qing Hao Alcohol Free, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Qing Hao Alcohol Free by Herbal Terra: Common Questions
Does Qing Hao Alcohol Free by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take during pregnancy?
What are the side effects?
Does it work for hay fever?
What is the active ingredient for?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Qing Hao Alcohol Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Qing Hao Alcohol Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Qing Hao Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sweet Annie 11 references
- Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects. J Ethnopharmacol 2000;73:487-93. PubMed
- Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop Med Hyg 2004;70:128-32. DOI
- Centers for Disease Control and Prevention (CDC). Hepatitis temporally associated with an herbal supplement containing artemisinin-Washington, 2008. MMWR Morb Mortal Wkly Rep 2009;58:854-8.
- Xing J, Kirby BJ, Whittington D, et al. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug Metabl Dispos 2012;40(9):1757-64. PubMed
- Savage RL, Hill GR, Barnes J, Kenyon SH, Tatley MV. Suspected hepatotoxicity with a supercritical carbon dioxide extract of Artemisia annua in grapeseed oil used in New Zealand. Front Pharmacol. 2019;10:1448. PubMed
- Ruperti-Repilado FJ, Haefliger S, Rehm S, et al. Danger of herbal tea: a case of acute cholestatic hepatitis due to Artemisia annua tea. Front Med (Lausanne). 2019;6:221. PubMed
- Yang J, Shen Z, Liu L, et al. Clinical efficacy and safety of Artesimia annua-Sublingual immunotherapy in seasonal allergic rhinitis patients based on different intervention time. Int Arch Allergy Immunol 2022;183(8):852-859.
- Kane NF, Kiani BH, Desrosiers MR, Towler MJ, Weathers PJ. Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro. J Ethnopharmacol 2022. DOI
- Feng Y, Cao Y, Liu Y, et al. Clinical efficacy and safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia-induced rhinoconjunctivitis. Am J Otolaryngol 2023;44(5):103942. PubMed
- Yang J, Wang W, Shen Z, et al. Efficacy and safety of Artemisia annua sublingual immunotherapy in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. Eur Arch Otorhinolaryngol. 2023;280(11):4939-4947. PubMed
- Shen Z, Zhang P, Kang W, et al. Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals. Am J Otolaryngol 2023;44(6):104002. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC