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Dietary supplement

Quassia 4:1 Extract Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Quassia 4:1 Extract Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Quassia 4:1 Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Quassia 4:1 Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for loss of appetite, digestive upset, head lice (topical).Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Quassia Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Quassia 4:1 Extract Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Quassia 4:1 Extract Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Quassia 4:1 Extract Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: quassia extract in powder form, a 4:1 concentration. There are no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Quassia product and its label doesn't state a use — see Quassia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for quassia's effectiveness in treating seborrheic dermatitis, lice, or rosacea is insufficient to rate. We don't have reliable data showing this product works for these purposes.

The evidence, ingredient by ingredient Quassia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Quassia taken by mouth can irritate mucous membranes and cause nausea and vomiting, especially at medicinal doses. Long-term use may cause vision changes and even blindness.

Smaller amounts used in foods are generally well tolerated. Quassia is rated likely unsafe during pregnancy because of traditional concerns and lack of safety data.

It's also rated likely unsafe while breastfeeding — there isn't enough information to know it's safe, so avoid it during nursing. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Quassia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Quassia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on diabetes medications (risk of low blood sugar), diuretics (risk of potassium loss), digoxin or other heart medications, or any acid-reducing drug including H2-blockers, antacids, or proton pump inhibitors.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Quassia extract is mainly used topically (on skin) where it appears well tolerated; taking it by mouth carries real risks, especially if you take diabetes drugs, diuretics, digoxin, or acid-reducing medications. Avoid it entirely during pregnancy or breastfeeding.

If you're interested in this product for any reason, talk it over with your doctor or pharmacist first — they can assess whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Quassia 4:1 Extract Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435212278
Net contents 4 Ounce(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 289816
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Quassia 4:1 Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
113
UPC/BARCODE
064435212278
IngredientAmount% DV
Quassia Extract, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Quassia 4:1 Extract Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Quassia 4:1 Extract Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Quassia 4:1 Extract Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container113 Amounts shown are per serving.

Quassia Extract, Powder

Interacts with
198 drugs
1000 mg per serving

Quassia is a tropical wood known for its very bitter taste, traditionally used as a digestive bitter and as a folk remedy for parasites and head lice....

Quassia Extract, Powder monograph & interactions
Interaction report

Quassia 4:1 Extract Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Quassia 4:1 Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
198Drugs
162 Moderate 36 Minor

Ingredients driving the most interactions

Quassia Extract, Powder 198

Individual Drug Interactions

The ingredients in Quassia 4:1 Extract Powder interact with 198 drugs. Click any drug to see the details.

1 of the 1 ingredient in Quassia 4:1 Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Quassia Extract, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Quassia 4:1 Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Quassia Extract, Powder6 drug types · 198 drugs

Antidiabetes Drugs

In animals, quassia extract reduced levels of fasting glucose. Theoretically, quassia might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, concomitant use with cardiac medications might increase the risk of therapeutic and adverse effects.

Likelihood Possible Evidence D
Diuretic Drugs

Overuse of quassia might compound diuretic-induced potassium loss. There is some concern that people taking quassia along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients.
Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), and hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Antacids

Theoretically, due to reports that quassia increases stomach acid, quassia might decrease the effectiveness of antacids.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, due to reports that quassia increases stomach acid, quassia might decrease the effectiveness of H2-blockers. The H2 blockers include cimetidine (Tagamet), ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid).

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, due to reports that quassia increases stomach acid, quassia might decrease the effectiveness of PPIs. PPIs include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium).

Likelihood Possible Evidence D
Quassia Extract, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Quassia 4:1 Extract Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Quassia 4:1 Extract Powder by TerraVita Premium Collection: Common Questions

Does Quassia 4:1 Extract Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Quassia 4:1 Extract Powder has a known interaction with 198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Quassia 4:1 Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does quassia extract do?
Quassia has been studied for skin conditions like seborrheic dermatitis, lice, and rosacea, but the evidence isn't strong enough yet to say whether it really works for these uses. It's most commonly applied to skin rather than taken by mouth.
Can I take this if I'm pregnant or breastfeeding?
No — quassia is rated likely unsafe during pregnancy because of traditional concerns and lack of safety data. It's also not safe while breastfeeding. Talk with your doctor or pharmacist about alternatives if you're pregnant or nursing.
What side effects might I notice?
Taken by mouth, quassia can irritate your throat and mouth and cause nausea and vomiting, especially at medicinal doses. Long-term use may cause vision changes and even blindness. When applied to skin, it's generally well tolerated with no reported adverse effects.
Is this powder safe to take long-term?
The safety data doesn't support long-term use by mouth. Large or prolonged doses can irritate your digestive tract and may cause serious side effects like vision problems. If you're considering ongoing use, discuss it with your doctor or pharmacist.
Does quassia work for lice?
The evidence for quassia treating lice is insufficient to rate — we don't have reliable data showing it works. If you need to treat lice, talk with your doctor or pharmacist about proven options.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Quassia 4:1 Extract Powder label
Go deeper

The Full Monographs Behind Quassia 4:1 Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Quassia

Interacts with 198 drugs

Quassia is a tropical wood known for its very bitter taste, traditionally used as a digestive bitter and as a folk remedy for parasites and head lice. Human evidence for these uses is limite...

Read the full Quassia monograph →
Sources

Sources & How We Checked

Quassia 4:1 Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Quassia 8 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Robbers JE, Speedie MK, Tyler VE. Pharmacognosy and Pharmacobiotechnology. Baltimore, MD: Williams & Wilkins, 1996.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Jensen O, Nielsen AO, Bjerregaard P. Pediculosis capitis treated with quassia tincture. Acta Derm Venereol 1978;58:557-9. DOI
  6. Diehl C, Ferrari A. Efficacy of topical 4% Quassia amara gel in facial seborrheic dermatitis:a randomized, double-blind, comparative study. J Drugs Dermatol. 2013;12(3):312-5.
  7. Ferrari A, Diehl C. Evaluation of the efficacy and tolerance of a topical gel with 4% quassia extract in the treatment of rosacea. J Clin Pharmacol. 2012;52(1):84-8. PubMed
  8. Husain GM, Singh PN, Singh RK, Kumar V. Antidiabetic activity of standardized extract of Quassia amara in nicotinamide-streptozotocin-induced diabetic rats. Phytother Res. 2011;25(12):1806-12.

See these in context on the Quassia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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