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Dietary supplement

Red Tea Rooibos 450 mg 4:1 Extract Ingredients & Drug Interactions

by TerraVita Premium Collection

Red Tea Rooibos 450 mg 4:1 Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Red Tea Rooibos 450 mg 4:1 Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Red Tea Rooibos 450 mg 4:1 Extract is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for caffeine-free beverage, antioxidant support, heart health.Based on those ingredients, 881 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Red Tea Rooibos Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: a concentrated rooibos extract at 450 mg per capsule in a 4:1 ratio, meaning the extract is four times more potent than the raw leaf material. Rooibos is a caffeine-free herbal tea from South Africa, traditionally brewed and now available here in capsule form as a dried, concentrated extract.

The capsule also contains gelatin and water as inactive ingredients (the materials that make up the capsule itself).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Rooibos product and its label doesn't state a use — see Rooibos's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on rooibos for six major health claims — age-related cognitive decline, hay fever, anxiety, cancer, heart disease, and diabetes — is not established enough for us to rate. That doesn't mean it doesn't work; it means the studies we have aren't solid enough yet to say one way or the other.

If you're considering this product for a specific condition, talk with your doctor about whether the research supports its use for your needs.

The evidence, ingredient by ingredient Rooibos

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rooibos tea is generally well tolerated in normal beverage amounts — the kind you'd brew from loose leaves or tea bags. However, concentrated extracts like this capsule haven't been studied much, so we can't say with confidence how safe long-term use at higher doses is.

One case report linked very heavy tea consumption (10 cups daily for over a year) to liver damage in a susceptible person; with a concentrated extract, the dose per dose is much higher, so talk with your provider before using this regularly. Pregnancy and lactation safety data on rooibos extracts isn't on file — check with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Rooibos

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rooibos.
  • The most serious interaction on file is rated Moderate.
  • For scale: 882 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist or doctor if you take any medications metabolized by your liver's main enzyme systems — that includes many blood pressure drugs, cholesterol medications, antidepressants, antihistamines, and beta-blockers. Also flag ACE inhibitors and atorvastatin specifically, as rooibos may increase their effects.

All of these interactions are rated Moderate in severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Rooibos extract may appeal to someone looking for a caffeine-free herbal supplement, but the concentrated form here interacts with a very large number of medications through liver enzyme inhibition. If you take any prescription drugs, clear this with your pharmacist or doctor first.

Because concentrated extracts haven't been well studied, it's worth discussing long-term or regular use with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Red Tea Rooibos 450 mg 4:1 Extract, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435212704
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 289451
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435212704
IngredientAmount% DV
Red Tea Rooibos Extract450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Red Tea Rooibos 450 mg 4:1 Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Red Tea Rooibos Extract

Interacts with
881 drugs
450 mg per serving

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early...

Red Tea Rooibos Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Red Tea Rooibos 450 mg 4:1 Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
881Drugs
881 Moderate

Ingredients driving the most interactions

Red Tea Rooibos Extract 881

Individual Drug Interactions

The ingredients in Red Tea Rooibos 450 mg 4:1 Extract interact with 881 drugs. Click any drug to see the details.

1 of the 1 ingredient in Red Tea Rooibos 450 mg 4:1 Extract interact with drugs. Each result below shows which ingredient is responsible. Red Tea Rooibos Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Red Tea Rooibos 450 mg 4:1 Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Red Tea Rooibos Extract7 drug types · 881 drugs

Ace Inhibitors (Aceis)

Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.

Likelihood Possible Evidence D
Red Tea Rooibos Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Red Tea Rooibos 450 mg 4:1 Extract, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection: Common Questions

Does Red Tea Rooibos 450 mg 4:1 Extract by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Red Tea Rooibos 450 mg 4:1 Extract has a known interaction with 881 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Red Tea Rooibos 450 mg 4:1 Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is rooibos caffeine-free?
Yes. Rooibos is naturally caffeine-free, so this extract won't give you the jolt or sleep disruption you'd get from caffeinated teas or coffee.
Can I take this if I'm on blood pressure or cholesterol medication?
Not without checking first. Rooibos interacts with ACE inhibitors (blood pressure drugs) and atorvastatin (a cholesterol drug) by potentially raising their levels in your body. Talk with your pharmacist or doctor before adding this supplement to see if it's safe for your specific medications.
What does 'concentrated 4:1 extract' mean?
It means the extract is four times more potent than the raw leaf — so each capsule delivers a lot more rooibos than you'd get brewing a cup of tea. That's why concentrated extracts carry more risk of interactions and side effects than casual tea drinking.
Does this help with anxiety or sleep?
The evidence we hold isn't strong enough to say. While rooibos is often marketed for relaxation, we don't have reliable data on whether it actually works for anxiety. If you're looking to treat anxiety, talk with your doctor about proven options.
Can I take this long-term?
Concentrated rooibos extracts haven't been studied much over the long haul, so we don't have solid safety data for regular use. One heavy tea drinker developed liver problems after very high consumption — talk with your provider before using this regularly to see what's right for you.
Is it safe in pregnancy?
We don't have enough data to know either way. While rooibos tea is considered safe as a casual beverage, we don't have safety information on concentrated extracts in pregnancy. Check with your doctor or pharmacist for personalized advice if you're pregnant or planning to be.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Red Tea Rooibos 450 mg 4:1 Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Red Tea Rooibos 450 mg 4:1 Extract label
Go deeper

The Full Monographs Behind Red Tea Rooibos 450 mg 4:1 Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rooibos

Interacts with 881 drugs

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early studies suggest possible benefits for he...

Read the full Rooibos monograph →
Sources

Sources & How We Checked

Red Tea Rooibos 450 mg 4:1 Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rooibos 4 references
  1. Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.
  2. Persson IA, Persson K, Hägg S, Andersson RG. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public Health Nutr. 2010;13(5):730-7. PubMed
  3. Reddy S, Mishra P, Qureshi S, Nair S, Straker T. Hepatotoxicity due to red bush tea consumption: a case report. J Clin Anesth. 2016;35:96-98. PubMed
  4. Patel O, Muller CJF, Joubert E, et al. Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Front Pharmacol. 2019;10:1243. PubMed

See these in context on the Rooibos monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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