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Dietary supplement

Riboflavin 100 mg Ingredients & Drug Interactions

by Swanson

Riboflavin 100 mg label
See full label image
Capsule Category: Vitamin
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Riboflavin 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Riboflavin 100 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Riboflavin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Riboflavin 100 mg by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Riboflavin 100 mg by Swanson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Riboflavin 100 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: riboflavin (vitamin B2), a B vitamin your body uses to convert food into energy and maintain healthy skin and eyes. The capsule also holds inactive ingredients — rice flour, gelatin, and calcium palmitate — which are standard fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Riboflavin product and its label doesn't state a use — see Riboflavin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness ratings on file for riboflavin. The evidence for its role in specific health conditions isn't established in our data.

The evidence, ingredient by ingredient Riboflavin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Riboflavin is generally well tolerated. Excess amounts are simply cleared through your urine.

The most common side effects are dose-related nausea and bright yellow urine discoloration (which is harmless). At very high doses, some people have reported diarrhea or increased urination, though these are rare.

Riboflavin is considered likely safe during pregnancy and breastfeeding at recommended amounts — in fact, your body needs it during both. If you're pregnant or breastfeeding and want to use a higher-dose supplement like this one, talk it over with your doctor or pharmacist first.

Side effects, ingredient by ingredient Riboflavin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Riboflavin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Tetracycline antibiotics are the main medication type to double-check before taking this product. These are commonly used for bacterial infections and acne.

If you're on any tetracycline, run it through the search tool on this page and confirm with your doctor or pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Riboflavin 100 mg is a straightforward B vitamin supplement that most people tolerate well. If you take tetracycline antibiotics (or any other prescription medications), check them against the interaction tool on this page before starting, then confirm with your own doctor or pharmacist.

Pregnant or breastfeeding? Touch base with your provider about whether this dose is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Riboflavin 100 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614010182
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD May 28, 2019
DSLD ID 202273
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Riboflavin 100 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
087614010182
IngredientAmount% DV
Riboflavin100 mg7692%

Other ingredients: Rice Flour, Gelatin, Calcium Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Aids in energy metabolism Supports healthy thyroid function Essential nutrient for vision health

Science-Backed Quality Since 1969

Energy and metabolism

100 mg per capsule

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one capsule per day with food and water.

Precautions

Warning: For adults only.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Vitamin B-2

FDA Statement of Identity

Vitamin Supplement

General

SW018 Rev 1 09 28 18

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Riboflavin 100 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Riboflavin 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Riboflavin 100 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Riboflavin

Interacts with
20 drugs
100 mg per serving Form: Vitamin B2

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin, Calcium Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Riboflavin 100 mg by Swanson Drug Interactions

Want to check YOUR meds against Riboflavin 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
20Drugs
20 Moderate

Ingredients driving the most interactions

Riboflavin 20

Individual Drug Interactions

The ingredients in Riboflavin 100 mg interact with 20 drugs. Click any drug to see the details.

1 of the 1 ingredient in Riboflavin 100 mg interact with drugs. Each result below shows which ingredient is responsible. Riboflavin

Each ingredient & the kinds of drugs it affects

For each ingredient in Riboflavin 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
Riboflavin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Riboflavin 100 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Riboflavin 100 mg by Swanson: Common Questions

Does Riboflavin 100 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Riboflavin 100 mg has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Riboflavin 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will riboflavin turn my urine yellow?
Yes — bright yellow urine is a normal, harmless side effect at higher doses like 100 mg. It's just excess riboflavin being cleared from your body and will stop once you stop taking it.
Is riboflavin safe during pregnancy?
Riboflavin is considered likely safe at recommended amounts during pregnancy, and your body actually needs it. If you're pregnant and want to take a 100 mg supplement, check with your doctor or pharmacist first to make sure the dose is right for you.
Can I take this while breastfeeding?
Riboflavin is likely safe while breastfeeding at standard doses — you need it for milk production. For a 100 mg supplement, ask your provider about whether that dose works for you.
What does riboflavin actually do?
Riboflavin (vitamin B2) helps your body turn food into energy and keeps your skin and eyes healthy. We don't have specific condition-related evidence on file for this product, but riboflavin is an essential nutrient.
Is riboflavin safe if I take it long-term?
Riboflavin is considered very safe — your body just clears excess through urine. Long-term use at normal doses is generally well tolerated, though nausea and yellow urine may occur at higher intakes.
What's in this capsule besides the riboflavin?
The capsule contains rice flour, gelatin, and calcium palmitate — these are inactive ingredients used as fillers and binders to hold the supplement together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Riboflavin 100 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Riboflavin 100 mg label
Go deeper

The Full Monographs Behind Riboflavin 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph →
Sources

Sources & How We Checked

Riboflavin 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Riboflavin 5 references
  1. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
  4. MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
  5. Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.

See these in context on the Riboflavin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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