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Dietary supplement

Riboflavin Vitamin B-2 100 mg Ingredients & Drug Interactions

by Basic Vitamins

Riboflavin Vitamin B-2 100 mg label
See full label image
Tablet Or Pill Category: Vitamin
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Riboflavin Vitamin B-2 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Riboflavin Vitamin B-2 100 mg is a dietary supplement by Basic Vitamins with 1 active ingredient. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Riboflavin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Riboflavin Vitamin B-2 100 mg by Basic Vitamins

Ask about any prescription or over-the-counter medication and we check it for interactions with Riboflavin Vitamin B-2 100 mg by Basic Vitamins — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Riboflavin Vitamin B-2 100 mg by Basic Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: riboflavin, a B vitamin also known as vitamin B-2. It delivers 100 mg per tablet.

The tablet also contains inactive ingredients — microcrystalline cellulose, hypromellose, magnesium stearate, silicon dioxide, polyethylene glycol, hydroxypropyl cellulose, and carnauba wax — which are standard binders, coatings, and fillers that help hold the tablet together and make it easier to swallow.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Riboflavin product and its label doesn't state a use — see Riboflavin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The effectiveness data for this product isn't established in our records. If you're considering riboflavin for a specific reason — whether that's energy, migraines, eye health, or something else — talk with your doctor or pharmacist about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Riboflavin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Riboflavin is very well tolerated overall; any excess your body doesn't use is simply removed in your urine. The most common side effects are dose-related nausea and bright yellow urine — both harmless.

Rarely, diarrhea or increased urination has been reported, mainly at higher doses. During pregnancy and breastfeeding, riboflavin is considered likely safe at recommended amounts because your body actually needs it.

If you're thinking about taking a high-dose supplement while pregnant or nursing, check with your doctor or pharmacist first to make sure the amount is right for you.

Side effects, ingredient by ingredient Riboflavin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Riboflavin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before you start if you take tetracycline antibiotics (like doxycycline or minocycline) — riboflavin may reduce their effectiveness. Talk with your pharmacist about whether you need to space out doses, adjust timing, or make any other changes to your routine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This straightforward B-vitamin supplement is a good choice if you need extra riboflavin and don't take tetracycline antibiotics. If you do take one of those antibiotics, confirm with your doctor or pharmacist that timing or spacing out the doses won't be an issue.

It's generally well tolerated with minimal side effects at this dose.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Riboflavin Vitamin B-2 100 mg, straight from the product label.

Brand Basic Vitamins
Barcode (UPC) 307610032200
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 292242
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Riboflavin Vitamin B-2 100 mg by Basic Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
100
UPC/BARCODE
307610032200
IngredientAmount% DV
Riboflavin100 mg7692%

Other ingredients: Microcrystalline Cellulose, Hypromellose, Magnesium Stearate, Silicon Dioxide, Polyethylene Glycol, Hydroxypropyl Cellulose, Carnauba Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of the reach of children.

Do not use if inner seal is missing or broken.

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Store in dry place at room temperature.

FDA Statement of Identity

Dietary Supplement

General Statements

High Quality Basics

Formulation

Gluten Free

Free of: Yeast, Gluten, Milk, Lactose, Sugar, Preservatives, Artificial Color, Artificial Flavor. Sodium Free.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one tablet daily or as directed by your healthcare practitioner.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Riboflavin Vitamin B-2 100 mg by Basic Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Riboflavin Vitamin B-2 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Riboflavin Vitamin B-2 100 mg by Basic Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.

Riboflavin

Interacts with
20 drugs
100 mg per serving Form: Vitamin B2

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Magnesium Stearate, Silicon Dioxide, Polyethylene Glycol, Hydroxypropyl Cellulose, Carnauba Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Riboflavin Vitamin B-2 100 mg by Basic Vitamins Drug Interactions

Want to check YOUR meds against Riboflavin Vitamin B-2 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
20Drugs
20 Moderate

Ingredients driving the most interactions

Riboflavin 20

Individual Drug Interactions

The ingredients in Riboflavin Vitamin B-2 100 mg interact with 20 drugs. Click any drug to see the details.

1 of the 1 ingredient in Riboflavin Vitamin B-2 100 mg interact with drugs. Each result below shows which ingredient is responsible. Riboflavin

Each ingredient & the kinds of drugs it affects

For each ingredient in Riboflavin Vitamin B-2 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
Riboflavin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Riboflavin Vitamin B-2 100 mg, from the product label.

Basic Vitamins

See all Basic Vitamins products
Name
Basic Drugs, Inc.
City
Vandalia
State
OH
ZipCode
45377
Phone Number
937-898-4010
Web Address
www.basicvitamins.com
Pharmacist Counseling Corner

Riboflavin Vitamin B-2 100 mg by Basic Vitamins: Common Questions

Does Riboflavin Vitamin B-2 100 mg by Basic Vitamins interact with any medications?
Yes. Based on its ingredients, Riboflavin Vitamin B-2 100 mg has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Riboflavin Vitamin B-2 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me nausea?
Nausea is dose-related, meaning it's more likely at higher doses than 100 mg. At this strength, most people tolerate it well. If you do feel queasy, taking it with food may help — ask your pharmacist if you're concerned.
Why will my urine turn yellow?
Bright yellow urine is harmless — it's just excess riboflavin your body is removing. It's a sign the vitamin is passing through, not that anything's wrong. The color will return to normal once you stop taking it.
Is this safe to take if I'm pregnant?
Riboflavin is considered likely safe during pregnancy at recommended amounts because your body needs it. If you're considering a high-dose supplement, talk with your doctor first to confirm the dose is appropriate for you.
Can I take this while breastfeeding?
Yes, riboflavin is considered likely safe while breastfeeding at recommended doses — it's actually needed. For higher-dose supplements, check with your provider about what's best for you and your baby.
What is riboflavin used for?
Riboflavin is a B vitamin your body needs for energy production and general health. The effectiveness of this product for specific conditions isn't established in our data — if you're taking it for a particular reason, talk with your doctor about whether the evidence supports that use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Riboflavin Vitamin B-2 100 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Riboflavin Vitamin B-2 100 mg label
Go deeper

The Full Monographs Behind Riboflavin Vitamin B-2 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph →
Sources

Sources & How We Checked

Riboflavin Vitamin B-2 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Riboflavin 5 references
  1. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
  4. MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
  5. Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.

See these in context on the Riboflavin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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