Rooibos Ingredients & Drug Interactions
by Alvita
What is this page for?
First and foremost: checking Rooibos against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Rooibos is a dietary supplement by Alvita with 1 active ingredient. Its ingredients are commonly taken for caffeine-free beverage, antioxidant support, heart health.Based on those ingredients, 879 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rooibos. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Rooibos by Alvita
Ask about any prescription or over-the-counter medication and we check it for interactions with Rooibos by Alvita — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Rooibos by Alvita
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Alvita Rooibos is a single-ingredient product: rooibos tea. There are no inactive ingredients listed.
Rooibos is a naturally caffeine-free herbal tea from South Africa, steeped as a beverage.
Does it work?
Couldn't assess
We hold no established evidence that rooibos works for any of the health claims linked to it—including age-related cognitive decline, hay fever, anxiety, cancer, heart disease, or diabetes. The effectiveness ratings in our data show insufficient reliable evidence for all of these conditions.
That doesn't mean it won't help, just that the science isn't there yet to say so.
How safe is it?
Well-documented data
Rooibos tea is generally well tolerated when you're drinking it in normal amounts as a beverage. Concentrated extracts haven't been well studied, so if you're considering one, check with your doctor or pharmacist first.
One case report described a man who drank 10 cups daily for over a year and developed liver problems and low platelet counts—a cautionary tale about very high, long-term intake. There's not enough data on rooibos in pregnancy or breastfeeding to say it's safe or unsafe; talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before using rooibos regularly if you take: ACE inhibitors or other blood pressure medications, atorvastatin or other cholesterol drugs, antidepressants, pain relievers, blood thinners, or any other prescription medication. Rooibos appears to slow your liver's ability to clear drugs processed through several enzyme pathways, which can raise drug levels and side effects.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Alvita Rooibos is a caffeine-free tea that's safe to drink occasionally. If you take prescription medications—especially blood pressure drugs, cholesterol medications, antidepressants, or blood thinners—you'll want to check with your doctor or pharmacist before making rooibos a regular habit, because it can slow how your liver clears certain drugs.
It's worth a quick conversation before you add it to your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Rooibos, straight from the product label.
| Brand | Alvita |
|---|---|
| Net contents | 24 Tea Bag(s); 1.83 Oz(s); 52 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jun 16, 2022 |
| DSLD ID | 268726 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Rooibos by Alvita, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Rooibos | 2.16 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Organic
A traditional South African antioxidant herbal tea
NSF Certified Gluten-Free Naturally caffeine free
Certified Organic by QAI.
Certified Gluten-Free by NSF.
Brand IP Statement(s)
Alvita Since 1922
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
NSF Certified Gluten-Free USDA Organic
Quality Assurance International Certified Organic Star-K (Kosher)
Suggested/Recommended/Usage/Directions
Preparation Place one tea bag in a cup and add 8 oz of water heated to 185 degrees. Cover and steep for 2 minutes. Gently squeeze tea bag and remove. Directions for use: We recommend 3 cups daily. Add sweetener if desired
How to brew 1. Pour 8 oz 2. Temp 185 degrees F 3. Steep 2 min
Formula
Star-K (Kosher)
Rooibos For more than 300 years, South Africans have brewed the fermented leaves of the rooibos shrub (Aspalathus linearis) into an herbal tea that is also commonly known as red bush tea. Its naturally sweet flavor and antioxidant content have earned rooibos tea a favored place among tea drinkers worldwide.
Alvita Rooibos Tea is made with premium-quality, organic rooibos leaves, and produces a mildly sweet flavor and aroma.
General Statements
The Alvita Story… In 1922, a new era for tea consumption began in America. The herb alfalfa, long known for its beneficial nutrients, was packaged in tea bags and sold to an emerging health food market. This product became known as Alvita and set the standard for future herbal teas. Today, Alvita represents more than forty single-ingredient teas, each one uniquely distinct, just like the individuals who drink them. Alvita chooses only the highest quality organic, wildcrafted, or cultivated botanicals, perfectly prepared to provide you with the best Mother Nature has to offer. Historical and scientific literature is painstakingly studied to ensure that the correct traditional plant and most appropriate servings are used, delivering premium flavor and quality. Herbs are gifts from the earth. Alvita takes its stewardship seriously by offering carefully harvested teas in earth-friendly packaging. Our beautifully illustrated boxes are made using recycled paperboard and our English, pillow style tea bags are oxygen bleached, not chlorine treated. You won’t find a better product, with a cleaner package… anywhere. Alvita… brewed with confidence, steeped in tradition.
100% Recycled Paperboard Recyclable
Precautions
Warning: If you are pregnant or nursing, taking any medication or have any medical condition, consult a healthcare professional before use.
Keep out of reach of children.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Rooibos by Alvita label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Rooibos by Alvita
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tea Bag(s) Dosage formOther (e.g. Tea Bag) Servings per container24 Amounts shown are per serving.
Rooibos
Interacts with879 drugs
Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early...
Rooibos monograph & interactionsRooibos by Alvita Drug Interactions
HelloPharmacist Interaction Report
Alvita Rooibos can interact with medications, mainly through rooibos's effects on liver enzymes that break down drugs.
The most serious concern is with drugs processed by CYP3A4 and CYP2C19 enzymes—rooibos appears to slow how your liver clears these medications, which can raise their levels in your blood and boost both their intended and unwanted effects. This includes atorvastatin (a cholesterol drug) and ACE inhibitors (blood pressure medications).
Read the full breakdown — every affected drug type, severity by severity
Rooibos also inhibits several other liver enzymes: CYP2D6, CYP1A2, and CYP2C9. Drugs metabolized by any of these pathways—antidepressants, some pain relievers, blood thinners, and many others—may build up to higher levels if you're drinking rooibos regularly.
In lab studies, the rooibos extract strongly blocked these enzyme systems.
Although most research here is in vitro (test-tube level), the clinical concern is real: in one small study, a single 400 mL cup of rooibos tea measurably inhibited the enzyme that controls blood pressure medications. If you take prescription medications regularly, run your exact drugs through the medication checker on this page before adding rooibos to your routine.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Rooibos?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Rooibos interact with 879 drugs. Click any drug to see the details.
1 of the 1 ingredient in Rooibos interact with drugs. Each result below shows which ingredient is responsible. Rooibos
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
Read the full Rooibos + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acalabrutinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Rooibos — through 1 ingredient. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Rooibos with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Rooibos
Ace Inhibitors (Aceis)
Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.
Atorvastatin (Lipitor)
Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.
Brand information
Manufacturer and brand details for Rooibos, from the product label.
Alvita
See all Alvita products- Name
- Twinlab Corporation
- City
- American Fork
- State
- UT
- ZipCode
- 84003
- Phone Number
- 1-800-645-5626
Rooibos by Alvita: Common Questions
Does Rooibos by Alvita interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is rooibos caffeine-free?
Can I drink rooibos if I'm pregnant or breastfeeding?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Rooibos’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Rooibos's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rooibos 4 references
- Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.
- Persson IA, Persson K, Hägg S, Andersson RG. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public Health Nutr. 2010;13(5):730-7. PubMed
- Reddy S, Mishra P, Qureshi S, Nair S, Straker T. Hepatotoxicity due to red bush tea consumption: a case report. J Clin Anesth. 2016;35:96-98. PubMed
- Patel O, Muller CJF, Joubert E, et al. Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Front Pharmacol. 2019;10:1243. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC