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Dietary supplement

Rooibos Ingredients & Drug Interactions

by Alvita

Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Rooibos is a dietary supplement by Alvita with 1 active ingredient. Its ingredients are commonly taken for caffeine-free beverage, antioxidant support, heart health.Based on those ingredients, 879 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rooibos. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Rooibos by Alvita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Alvita Rooibos is a single-ingredient product: rooibos tea. There are no inactive ingredients listed.

Rooibos is a naturally caffeine-free herbal tea from South Africa, steeped as a beverage.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: traditional South African antioxidant herbal tea.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no established evidence that rooibos works for any of the health claims linked to it—including age-related cognitive decline, hay fever, anxiety, cancer, heart disease, or diabetes. The effectiveness ratings in our data show insufficient reliable evidence for all of these conditions.

That doesn't mean it won't help, just that the science isn't there yet to say so.

The evidence, ingredient by ingredient Rooibos

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rooibos tea is generally well tolerated when you're drinking it in normal amounts as a beverage. Concentrated extracts haven't been well studied, so if you're considering one, check with your doctor or pharmacist first.

One case report described a man who drank 10 cups daily for over a year and developed liver problems and low platelet counts—a cautionary tale about very high, long-term intake. There's not enough data on rooibos in pregnancy or breastfeeding to say it's safe or unsafe; talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Rooibos

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rooibos.
  • The most serious interaction on file is rated Moderate.
  • For scale: 880 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using rooibos regularly if you take: ACE inhibitors or other blood pressure medications, atorvastatin or other cholesterol drugs, antidepressants, pain relievers, blood thinners, or any other prescription medication. Rooibos appears to slow your liver's ability to clear drugs processed through several enzyme pathways, which can raise drug levels and side effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Alvita Rooibos is a caffeine-free tea that's safe to drink occasionally. If you take prescription medications—especially blood pressure drugs, cholesterol medications, antidepressants, or blood thinners—you'll want to check with your doctor or pharmacist before making rooibos a regular habit, because it can slow how your liver clears certain drugs.

It's worth a quick conversation before you add it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rooibos, straight from the product label.

Brand Alvita
Net contents 24 Tea Bag(s); 1.83 Oz(s); 52 Gram(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 268726
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rooibos by Alvita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tea Bag(s)
Maximum serving Sizes:
1 Tea Bag(s)
Servings per container
24
IngredientAmount% DV
Rooibos2.16 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Organic

A traditional South African antioxidant herbal tea

NSF Certified Gluten-Free Naturally caffeine free

Certified Organic by QAI.

Certified Gluten-Free by NSF.

Brand IP Statement(s)

Alvita Since 1922

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

NSF Certified Gluten-Free USDA Organic

Quality Assurance International Certified Organic Star-K (Kosher)

Suggested/Recommended/Usage/Directions

Preparation Place one tea bag in a cup and add 8 oz of water heated to 185 degrees. Cover and steep for 2 minutes. Gently squeeze tea bag and remove. Directions for use: We recommend 3 cups daily. Add sweetener if desired

How to brew 1. Pour 8 oz 2. Temp 185 degrees F 3. Steep 2 min

Formula

Star-K (Kosher)

Rooibos For more than 300 years, South Africans have brewed the fermented leaves of the rooibos shrub (Aspalathus linearis) into an herbal tea that is also commonly known as red bush tea. Its naturally sweet flavor and antioxidant content have earned rooibos tea a favored place among tea drinkers worldwide.

Alvita Rooibos Tea is made with premium-quality, organic rooibos leaves, and produces a mildly sweet flavor and aroma.

General Statements

The Alvita Story… In 1922, a new era for tea consumption began in America. The herb alfalfa, long known for its beneficial nutrients, was packaged in tea bags and sold to an emerging health food market. This product became known as Alvita and set the standard for future herbal teas. Today, Alvita represents more than forty single-ingredient teas, each one uniquely distinct, just like the individuals who drink them. Alvita chooses only the highest quality organic, wildcrafted, or cultivated botanicals, perfectly prepared to provide you with the best Mother Nature has to offer. Historical and scientific literature is painstakingly studied to ensure that the correct traditional plant and most appropriate servings are used, delivering premium flavor and quality. Herbs are gifts from the earth. Alvita takes its stewardship seriously by offering carefully harvested teas in earth-friendly packaging. Our beautifully illustrated boxes are made using recycled paperboard and our English, pillow style tea bags are oxygen bleached, not chlorine treated. You won’t find a better product, with a cleaner package… anywhere. Alvita… brewed with confidence, steeped in tradition.

100% Recycled Paperboard Recyclable

Precautions

Warning: If you are pregnant or nursing, taking any medication or have any medical condition, consult a healthcare professional before use.

Keep out of reach of children.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Rooibos by Alvita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Rooibos by Alvita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tea Bag(s) Dosage formOther (e.g. Tea Bag) Servings per container24 Amounts shown are per serving.

Rooibos

Interacts with
879 drugs
2.16 Gram(s) per serving

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early...

Rooibos monograph & interactions
Interaction report

Rooibos by Alvita Drug Interactions

Want to check YOUR meds against Rooibos?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
879Drugs
879 Moderate

Ingredients driving the most interactions

Rooibos 879

Each ingredient & the kinds of drugs it affects

For each ingredient in Rooibos with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rooibos7 drug types · 879 drugs

Ace Inhibitors (Aceis)

Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Rooibos, from the product label.

Alvita

See all Alvita products
Name
Twinlab Corporation
City
American Fork
State
UT
ZipCode
84003
Phone Number
1-800-645-5626
Pharmacist Counseling Corner

Rooibos by Alvita: Common Questions

Does Rooibos by Alvita interact with any medications?
Yes. Based on its ingredients, Rooibos has a known interaction with 879 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rooibos contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is rooibos caffeine-free?
Yes. Rooibos is naturally caffeine-free, so you can drink it anytime without worrying about caffeine jitters or sleep disruption.
Can I drink rooibos if I'm pregnant or breastfeeding?
There isn't enough research data to say whether rooibos is safe or unsafe during pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice, especially if you're considering it as a regular habit rather than an occasional cup.
What happens if I drink a lot of rooibos?
In normal beverage amounts, it's generally well tolerated. One case report describes someone who drank 10 cups daily for over a year and developed liver problems and low platelet counts. Concentrated extracts haven't been studied as thoroughly, so use caution with those and check with your doctor or pharmacist before regular use.
Does rooibos help with anxiety or sleep?
The evidence we hold shows insufficient reliable evidence that rooibos works for anxiety. If you're considering it for sleep or stress, talk with your doctor or pharmacist about whether it's a good fit for your situation.
Can I use concentrated rooibos extract instead of tea?
Concentrated extracts haven't been well studied, so we don't have safety data for them. Check with your doctor or pharmacist before using one regularly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rooibos is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rooibos label
Sources

Sources & How We Checked

Rooibos's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rooibos 4 references
  1. Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.
  2. Persson IA, Persson K, Hägg S, Andersson RG. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public Health Nutr. 2010;13(5):730-7. PubMed
  3. Reddy S, Mishra P, Qureshi S, Nair S, Straker T. Hepatotoxicity due to red bush tea consumption: a case report. J Clin Anesth. 2016;35:96-98. PubMed
  4. Patel O, Muller CJF, Joubert E, et al. Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Front Pharmacol. 2019;10:1243. PubMed

See these in context on the Rooibos monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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