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Dietary supplement

Rosemary Ingredients & Drug Interactions

by Zongle Therapeutics

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Rosemary is a dietary supplement by Zongle Therapeutics with 1 active ingredient. Its ingredients are commonly taken for memory and concentration, digestive upset, hair growth.Based on those ingredients, 372 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rosemary. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Rosemary by Zongle Therapeutics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: rosemary. It's a liquid form of the herb, prepared with steam-distilled rosemary oil.

In traditional and culinary use, rosemary has been valued for its flavor and aroma; here it's being used in concentrated form as a supplement.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: healthy digestion and respiratory function.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Digestive support, Respiratory health.
  • The closest evidence on file: Rosemary is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI) (Natural Medicines).

The only effectiveness rating we have for rosemary is for memory support — the evidence rates it as possibly effective. For other uses listed in our data (age-related cognitive decline, alopecia areata, and fatty liver disease), the evidence is insufficient to make a rating.

The data we hold doesn't establish effectiveness for other potential uses you may have heard about.

The evidence, ingredient by ingredient Rosemary

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rosemary is generally well tolerated in normal culinary amounts. Concentrated extracts and undiluted essential oils call for caution.

Food amounts are likely fine during pregnancy and breastfeeding, but medicinal or large doses should be avoided in pregnancy, and there isn't enough safety data on medicinal doses during breastfeeding to know either way — talk with your pharmacist or doctor about what's right for you. Side effects can occur, especially with topical use or when the herb is inhaled or used in the mouth.

Allergic reactions (including allergic contact dermatitis), lip and gum swelling, and occupational asthma have been reported. The undiluted oil and rosemary's camphor content might trigger seizures in susceptible individuals.

Topical use can cause photosensitivity (sun sensitivity) and skin reactions in some people.

Side effects, ingredient by ingredient Rosemary

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rosemary.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 372 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check your medications if you're on blood thinners or antiplatelet drugs (moderate risk of bleeding), diabetes medication (moderate risk of low blood sugar), aspirin, or salicylate-containing pain relievers like Trilisate or Disalcid (moderate risk of additive effects). Also flag any medications processed by your liver's CYP1A2 enzyme (minor risk of reduced drug levels) — your pharmacist can look those up.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, diabetes medication, or salicylate pain relievers, check with us before starting this product. The evidence supports rosemary for memory, but it's not established for other uses.

Keep it to culinary amounts if you're pregnant or breastfeeding, and watch for allergic skin reactions or sensitivity to sun. Your pharmacist can help you weigh whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rosemary, straight from the product label.

Brand Zongle Therapeutics
Net contents 0.5 Fluid Ounce(s); 15 mL
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 277117
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rosemary by Zongle Therapeutics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
250
IngredientAmount% DV
Rosemary60 mg--

Other ingredients: Rosemary Oil, Steam-Distilled

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

For aromatic, topical or internal use.

For internal use dilute one drop in 4 fl. oz. of liquid.

Formulation

Promotes healthy digestion Promotes healthy respiratory function Helps reduce nervous tension and fatigue

100% pure

Therapeutic Grade

Origin: Spain Bottled in USA

Artificial ingredients free GMO free Gluten free Preservatives free Paraben free

Vegan

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: Possible skin sensitivity.

Keep out of reach of children.

If you are pregnant, nursing, or under a doctor's care, consult your physician.

Avoid contact with eyes, inner ears, and sensitive areas.

Formula

Rosmarinus officinalis

FDA Statement of Identity

Essential Oil Supplement

See for yourself

Rosemary by Zongle Therapeutics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Rosemary by Zongle Therapeutics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container250 Amounts shown are per serving.

Rosemary

Interacts with
372 drugs
60 mg per serving Form: Rosemary, Rosemary

Rosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory...

Rosemary monograph & interactions

Other (inactive) ingredients: Rosemary Oil, Steam-Distilled. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rosemary by Zongle Therapeutics Drug Interactions

Want to check YOUR meds against Rosemary?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
372Drugs
212 Moderate 160 Minor

Ingredients driving the most interactions

Rosemary 372

Each ingredient & the kinds of drugs it affects

For each ingredient in Rosemary with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rosemary6 drug types · 372 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that rosemary inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that rosemary extract can decrease blood glucose levels in diabetic models. However, research in humans is conflicting. Although rosemary powder decreased blood glucose levels in healthy adults, no change in blood glucose levels was seen in adults with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
Aspirin

Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Rosemary is reported to contain salicylates.

Likelihood Possible Evidence D
Choline Magnesium Trisalicylate (Trilisate)

Theoretically, rosemary might have additive effects with salicylate-containing drugs such as choline magnesium trisalicylate.
Rosemary is reported to contain salicylate.

Likelihood Possible Evidence D
Salsalate (Disalcid)

Theoretically, rosemary might have additive effects with salicylate-containing drugs such as salsalate.
Rosemary is reported to contain salicylate.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that rosemary induces CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for Rosemary, from the product label.

Zongle Therapeutics

See all Zongle Therapeutics products
Name
Zongle Therapeutics
Web Address
www.zongletherapeutics.com
Pharmacist Counseling Corner

Rosemary by Zongle Therapeutics: Common Questions

Does Rosemary by Zongle Therapeutics interact with any medications?
Yes. Based on its ingredients, Rosemary has a known interaction with 372 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rosemary contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does rosemary actually work for memory?
The evidence rates rosemary as possibly effective for memory support. For other uses like age-related cognitive decline or fatty liver disease, we don't have enough reliable evidence to say whether it works.
Can I use this if I'm pregnant?
Food amounts are likely fine, but medicinal or large doses should be avoided in pregnancy. If you're thinking about taking this as a supplement, talk with your doctor or pharmacist first — they can give you personalized advice based on your situation.
Can I use this while breastfeeding?
Food amounts are likely fine, but there isn't enough safety data on medicinal doses during breastfeeding to know either way. Check with your pharmacist or doctor before taking this as a supplement.
What side effects might I notice?
Allergic reactions can happen, especially on the skin or in the mouth — swelling of the lips and gums has been reported. If you inhale rosemary dust at work, occupational asthma is a rare but documented risk. The undiluted oil might trigger seizures in susceptible people, and some individuals experience sun sensitivity with topical use.
Is this safe to use every day?
In normal culinary amounts, rosemary is generally well tolerated. Concentrated extracts and undiluted essential oils require caution with regular use. If you're considering daily supplemental use, talk with your pharmacist or doctor first, especially if you take any medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rosemary is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rosemary label
Sources

Sources & How We Checked

Rosemary's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rosemary 20 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  5. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  6. Cartier LC, Lehrer A, Malo JL. Occupational asthma caused by aromatic herbs. Allergy 1996;51:647-9. DOI
  7. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
  8. Swain AR, Dutton SP, Truswell AS. Salicylates in foods. J Am Diet.Assoc 1985;85(8):950-60. DOI
  9. Zhu BT, Loder DP, Cai MX, et al. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. Carcinogenesis 1998;19(10):1821-7. PubMed
  10. Debersac P, Heydel JM, Amiot MJ, et al. Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns. Food Chem Toxicol 2001;39(9):907-18. PubMed
  11. Debersac P, Vernevaut MF, Amiot MJ, et al. Effects of a water-soluble extract of rosemary and its purified component rosmarinic acid on xenobiotic-metabolizing enzymes in rat liver. Food Chem Toxicol 2001;39(2):109-17. PubMed
  12. Lee JJ, Jin YR, Lee JH, et al. Antiplatelet activity of carnosic acid, a phenolic diterpene from Rosmarinus officinalis. Planta Med 2007;73(2):121-7.
  13. Yamamoto J, Yamada K, Naemura A, et al. Testing various herbs for antithrombotic effect. Nutrition 2005;21(5):580-7. PubMed
  14. Naemura A, Ura M, Yamashita T, et al. Long-term intake of rosemary and common thyme herbs inhibits experimental thrombosis without prolongation of bleeding time. Thromb Res 2008;122(4):517-22. PubMed
  15. Lee JJ, Jin YR, Lim Y, et al. Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. Vascul Pharmacol 2006;45:148-53. PubMed
  16. Bakirel, T., Bakirel, U., Keles, O. U., Ulgen, S. G., and Yardibi, H. In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. J Ethnopharmacol 2-28-2008;116(1):64-73. PubMed
  17. Erenmemisoglu, A., Saraymen, R., and Ustun, S. Effect of a Rosmarinus officinalis leave extract on plasma glucose levels in normoglycaemic and diabetic mice. Pharmazie 1997;52(8):645-646.
  18. Valones MAA, Silva ICG, Gueiros LAM, Leão JC, Caldas AF Jr, Carvalho AAT. Clinical assessment of rosemary-based toothpaste (Rosmarinus officinalis Linn.): A randomized controlled double-blind study. Braz Dent J. 2019;30(2):146-151. PubMed
  19. Quirarte-Báez SM, Zamora-Perez AL, Reyes-Estrada CA, et al. A shortened treatment with rosemary tea (rosmarinus officinalis) instead of glucose in patients with diabetes mellitus type 2 (TSD). J Popul Ther Clin Pharmacol. 2019;26(4):e18-e28.
  20. Al Jamal A. Effect of rosemary (Rosmarinus officinalis) on lipid profiles and blood glucose in human diabetic patients (type-2). African J. Biochem. Res. 2014;8(8):147-50. DOI

See these in context on the Rosemary monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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