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Dietary supplement

Royal Jelly 750 mg Ingredients & Drug Interactions

by Simply Supplements

Royal Jelly 750 mg label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Royal Jelly 750 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Royal Jelly 750 mg is a dietary supplement by Simply Supplements with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, skin health and wound care, immune support.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Royal Jelly Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Royal Jelly 750 mg by Simply Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Royal Jelly 750 mg by Simply Supplements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Royal Jelly 750 mg by Simply Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: royal jelly extract at 750 mg per tablet. Royal jelly is a nutrient-rich secretion produced by honeybees; it's been used traditionally in supplements for various health purposes.

The tablet also includes three inactive ingredients — dicalcium phosphate, microcrystalline cellulose, and magnesium stearate — which serve as fillers and binders to hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Royal Jelly's overall clinical evidence instead.

Moderate

Some clinical evidence supports Royal Jelly for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Menopausal symptoms — rated "Possibly Effective" (Natural Medicines).

The evidence for royal jelly's effectiveness is mixed and limited. It's rated possibly effective for menopausal symptoms — meaning some evidence suggests it may help, but more research is needed to be sure.

For allergic rhinitis (hay fever), physical performance, and diabetes, the evidence suggests it's probably not effective. For hair loss (androgenic alopecia), there simply isn't enough reliable evidence to say either way.

The evidence, ingredient by ingredient Royal Jelly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Royal jelly is generally well tolerated in most people. The biggest safety concern is allergic reaction, especially in people with a history of asthma or atopy (a tendency toward allergic conditions).

Common allergic symptoms include itching, hives, eczema, swelling of the eyelids or face, and shortness of breath. Rarely, it can cause serious reactions like anaphylaxis or a severe asthma attack.

There's also one case report of hemorrhagic colitis (bleeding in the colon) with abdominal pain and bloody diarrhea after royal jelly use, though symptoms resolved within two weeks of stopping it. Because there isn't enough safety information, the data advises against use during pregnancy and while breastfeeding — talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Royal Jelly

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Royal Jelly.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on warfarin (Coumadin) or any other blood thinner — royal jelly may increase bleeding risk. Also confirm if you're taking antihypertensive drugs (blood pressure medications), as royal jelly might lower your blood pressure further and cause dizziness or weakness.

No interactions are documented for the inactive ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Royal Jelly 750 mg may appeal to someone looking for support with menopausal symptoms, though the evidence is limited. If you take warfarin or other blood thinners, or medications for high blood pressure, you'll want to check with your doctor or pharmacist first — the interaction risk is real.

Anyone with a history of asthma or allergies should be especially cautious. Have a conversation with your own doctor or pharmacist before starting this supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Royal Jelly 750 mg, straight from the product label.

Brand Simply Supplements
Barcode (UPC) 5060208411720
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 22069
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Royal Jelly 750 mg by Simply Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
UPC/BARCODE
5060208411720
IngredientAmount% DV
Royal Jelly Extract250 mg--

Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

CODE S824

Suggested/Recommended/Usage/Directions

DIRECTIONS Take one to two tablets daily as a food supplement or as directed by a healthcare professional.

Storage

Store in a cool dry place.

Precautions

Do not use if the seal is broken. Do not exceed stated dose.

Keep away from children at all times.

Pregnant and Lactating women should consult a Doctor before use.

Food supplement: This product should not be used as a substitute for a varied diet. Caution: If under medical supervision please consult a Doctor before use. Discontinue use if adverse reactions occur.

General Statements

PRICE MATCH GUARANTEE! Lowest Price in the UK or we will refund the difference plus 10%!

AUTODESPATCH Save 10% by having your supplements conveniently scheduled and delivered automatically. SAME DAY DESPATCH We will ensure your order is despatched on the day of receipt (before 12.30pm) and that all orders after 12.30pm are despatched within 24 hours. All sent 1st class!

BUY ONE GET ONE FREE on everything!

Seals/Symbols

SimplySupplements(TM) High Quality Vitamins & Minerals

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Royal Jelly 750 mg by Simply Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Royal Jelly 750 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Royal Jelly 750 mg by Simply Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Royal Jelly Extract

Interacts with
174 drugs
250 mg per serving

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune su...

Royal Jelly Extract monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Royal Jelly 750 mg by Simply Supplements Drug Interactions

Want to check YOUR meds against Royal Jelly 750 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Royal Jelly Extract 174

Individual Drug Interactions

The ingredients in Royal Jelly 750 mg interact with 174 drugs. Click any drug to see the details.

1 of the 1 ingredient in Royal Jelly 750 mg interact with drugs. Each result below shows which ingredient is responsible. Royal Jelly Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Royal Jelly 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Royal Jelly Extract2 drug types · 174 drugs

Antihypertensive Drugs

Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that royal jelly might lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.

Likelihood Possible Evidence D
Royal Jelly Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Royal Jelly 750 mg, from the product label.

Simply Supplements

See all Simply Supplements products
Name
Simply Supplements
Street Address
PO Box 204
City
Guernsey
ZipCode
GY1 3NB
Pharmacist Counseling Corner

Royal Jelly 750 mg by Simply Supplements: Common Questions

Does Royal Jelly 750 mg by Simply Supplements interact with any medications?
Yes. Based on its ingredients, Royal Jelly 750 mg has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Royal Jelly 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take royal jelly if I have asthma or allergies?
Royal jelly can trigger serious allergic reactions in people with a history of asthma or atopy (a tendency toward allergies), with symptoms ranging from itching and hives to shortness of breath and, in rare cases, anaphylaxis. If you have asthma or known allergies, talk with your doctor or pharmacist before starting this supplement.
Will royal jelly help my menopausal symptoms?
Royal jelly is rated possibly effective for menopausal symptoms, meaning some evidence suggests it may help, but research is still limited. It's worth discussing with your doctor to see if it's a reasonable option for your situation.
Can I take royal jelly if I'm pregnant or breastfeeding?
There isn't enough safety information to know whether royal jelly is safe during pregnancy or while breastfeeding. The data advises against use in both cases — talk with your doctor or pharmacist for personalized advice if you're in either situation.
What's the difference between royal jelly and bee pollen or honey?
Royal jelly is a nutrient-dense secretion made by honeybees specifically to feed the queen bee. Bee pollen and honey are different bee products with their own properties — this supplement contains only royal jelly extract.
Are there any side effects I should watch for?
Most people tolerate royal jelly well. The main concern is allergic symptoms — itching, hives, swelling, shortness of breath — especially if you have a history of allergies or asthma. Rarely, it can cause more serious reactions or, in one documented case, bleeding in the colon with bloody diarrhea.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Royal Jelly 750 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Royal Jelly 750 mg label
Go deeper

The Full Monographs Behind Royal Jelly 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Royal Jelly

Interacts with 174 drugs

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune support, but solid human evidence is limit...

Read the full Royal Jelly monograph →
Sources

Sources & How We Checked

Royal Jelly 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Royal Jelly 14 references
  1. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
  2. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
  3. Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
  4. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
  5. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
  6. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
  7. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
  8. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
  9. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  10. Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
  11. Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
  12. Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
  13. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
  14. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

See these in context on the Royal Jelly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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