SAMe 400 mg By Source Naturals Overview & Drug Interactions
Check For Interactions With SAMe 400 mg
Supplement: SAMe 400 mg by Source Naturals
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
SAMe
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding SameIngredient Group | SAMe |
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Category | non-nutrient/non-botanical |
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SAMe Disulfate Tosylate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Drugs that interact with SAMe 400 mg by Source Naturals
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
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Minimum serving Sizes: |
1 Tablet(s)
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Maximum serving Sizes: |
1 Tablet(s)
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Servings per container | 30 |
UPC/BARCODE | 021078014003 |
Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
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SAMe |
400 mg
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SAMe |
--
|
SAMe Disulfate Tosylate |
800 mg
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SAMe |
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Other Ingredients: |
Cellulose
Mannitol
Hydroxypropyl Methylcellulose Phthalate
Citric Acid
Silica
Stearic Acid
Triacetin
Sodium Starch Glyconate
Croscarmellose Sodium
Titanium Dioxide
yellow Ochre
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Label Statments:
Formulation |
- Double Strength
- Supports joint comfort, function and mobility
- Suitable for vegetarians.
- Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, preservatives, or artificial flavor or fragrance.
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FDA Statement of Identity |
- Dietary Supplement
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Formula |
- S-adenosyl-L-methionine
- Source Naturals SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients.
Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. SAMe helps to form proteoglycans, which are used to renew the matrix of cartilage.
The studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier, where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe also plays a role in transmethylation. Transmethylation reactions affect the synthesis, activation, and metabolism of various biological molecules.
Some compounds that SAMe methylates are phospholipids. This is a fundamental step in the mediation of cell to cell communication.
SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. However, levels of SAMe tend to decline with age.
- S-adenosyl-L-methionine
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Suggested/Recommended/Usage/Directions |
- Suggested Use: 1 tablet 1 to 3 times daily. Take tablets on an empty stomach.
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Precautions |
- Warning: If you are pregnant, may become pregnant, breastfeeding or are taking antidepressant medication, consult your physician before using this product.
- Use this product under medical supervision if you have bipolar disorder. In small percentage of people this product may cause nausea or gastrointestinal upset. If you experience discomfort, discontinue use.
Do not use if either tamper-evident seal is broken or missing.
- Keep out of the reach of children.
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Brand IP Statement(s) |
- Copyright Source Naturals, Inc.
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FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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Brand Information
Manufactured for | |
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Name | Source Naturals, Inc. |
Street Address | P. O. Box 2118 |
City | Santa Cruz |
State | CA |
ZipCode | 95062 |
Web Address | www.sourcenaturals.com |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.