Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Sarpagandha Powder Ingredients & Drug Interactions

by Vedic Care

Sarpagandha Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sarpagandha Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Sarpagandha Powder is a dietary supplement by Vedic Care with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, anxiety and stress, insomnia.Based on those ingredients, 843 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sarpagandha root powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sarpagandha Powder by Vedic Care

Ask about any prescription or over-the-counter medication and we check it for interactions with Sarpagandha Powder by Vedic Care — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sarpagandha Powder by Vedic Care

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Sarpagandha Powder contains one active ingredient: Sarpagandha root powder, which is Indian snakeroot. This plant has been used in traditional medicine, though modern evidence for its effectiveness remains limited.

There are no inactive ingredients listed for this product.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Indian Snakeroot product and its label doesn't state a use — see Indian Snakeroot's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for Indian snakeroot is insufficient to establish whether it works for any of the conditions mentioned — abdominal pain, insomnia, insect bites, or psychosis. We don't have reliable data in hand to say whether it helps or doesn't.

If you're considering this for a specific health concern, talk with your doctor about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Indian Snakeroot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Indian snakeroot contains potent alkaloids and should only be used under medical supervision. The product carries serious safety cautions: avoid it during pregnancy, as its alkaloids may harm the developing baby, and avoid it while breastfeeding, since reserpine (one of its active compounds) passes into breast milk.

Common side effects from oral use include abdominal pain, slow heartbeat, nasal congestion, diarrhea, low blood pressure, increased appetite, nightmares, drowsiness, and weight gain. Rare but serious adverse effects include irregular heartbeat, seizures, depression, and heart attack.

Depression is a particular concern, especially at higher doses or with longer use — though research suggests it's less likely if you take it for fewer than 40 days.

Side effects, ingredient by ingredient Indian Snakeroot

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Indian Snakeroot.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; Parkinson's medications.
  • For scale: 843 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Sarpagandha Powder, double-check with your doctor or pharmacist if you take beta-blockers, antipsychotic drugs, levodopa, digoxin, sedating medications, blood pressure medications, blood thinners or antiplatelet drugs, or any medications broken down by your liver's CYP2D6 pathway. Major-severity interactions are documented with the first four types.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a potent herbal product meant for use under medical supervision only, not as a self-directed supplement. It carries Major-severity interactions with heart medications, antipsychotics, and Parkinson's drugs, as well as Moderate risks with blood pressure and blood-thinning medications.

It's off-limits in pregnancy and breastfeeding. Talk with your doctor or pharmacist before adding this to your routine — especially if you take any prescription medications or have heart, blood pressure, or mood concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sarpagandha Powder, straight from the product label.

Brand Vedic Care
Barcode (UPC) 6860918216108
Net contents 100 Gram(s); 3.52 Ounce(s)
Market status On market
Date entered into DSLD May 22, 2021
DSLD ID 247730
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sarpagandha Powder by Vedic Care, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
50
UPC/BARCODE
6860918216108
IngredientAmount% DV
Sarpagandha root powder2 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Halal India www.Halalindia.com GMP Certified Good Manufacturing Practice

Formula

Halal India www.Halalindia.com

Indian Snakeroot Plant part used - root

Ingredients: Each 100 g Contains- Sarpagandha (rauvolfia serpentina) root powder - 100 g

Formulation

GMO free Paraben free

Suitable for vegetarians

Pure & natural Manufactured in India

"Product tested for heavy metals in accordance with permissible limits outlined by American National Standards Institute"

Heavy metal tested

Extreme fine granularity

General Statements

C.No. RA574-AYU

For comments/feedback: [email protected] 1-612-88-VEDIC

Health tip: Practicing mindfulness has lasting physical and psychological benefits that are very much in line with the benefits of yoga. You will feel more calm and relaxed and less stressed and anxious.

Storage

Store in a cool dark place and in an air-tight container. Avoid exposure to moisture.

Precautions

Keep out of reach of children.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for use: Take 1.0g - 2.0g with warm water up to twice daily.

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sarpagandha Powder by Vedic Care label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sarpagandha Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sarpagandha Powder by Vedic Care

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Sarpagandha root powder

Interacts with
843 drugs
2 Gram(s) per serving

Indian snakeroot is a traditional Ayurvedic plant that contains reserpine, a compound with real blood-pressure-lowering and sedative effects. Because...

Sarpagandha root powder monograph & interactions
Interaction report

Sarpagandha Powder by Vedic Care Drug Interactions

Want to check YOUR meds against Sarpagandha Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
843Drugs
83 Major 760 Moderate

Ingredients driving the most interactions

Sarpagandha root powder 843

Individual Drug Interactions

The ingredients in Sarpagandha Powder interact with 843 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sarpagandha Powder interact with drugs. Each result below shows which ingredient is responsible. Sarpagandha root powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Sarpagandha Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sarpagandha root powder13 drug types · 843 drugs

Antipsychotic Drugs

Theoretically, concomitant use might increase the risk of adverse effects.
Concomitant use of neuroleptics with Indian snakeroot may potentiate the effects of these drugs, as well as the alkaloid constituents of Indian snakeroot.

Likelihood Probable Evidence D
Beta-Blockers

Theoretically, taking Indian snakeroot with beta-blockers might increase the risk of bradycardia and/or hypotension.
Indian snakeroot contains small amounts of reserpine. Reserpine causes catecholamine-depletion. Concomitant use of Indian snakeroot and beta-blockers might increase the risk or bradycardia and/or hypotension.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, taking Indian snakeroot with digoxin might increase the risk of bradycardia.
Bradycardia has been reported in clinical trials using Indian snakeroot. Concomitant use of digoxin with Indian snakeroot might potentiate this effect.

Likelihood Probable Evidence D
Levodopa

Theoretically, taking Indian snakeroot with levodopa may reduce the effectiveness of levodopa.
Extrapyramidal motor symptoms and Parkinson-like symptoms have been reported in clinical trials using Indian snakeroot. Concomitant use of Indian snakeroot with levodopa may reduce the effectiveness of levodopa and increase extrapyramidal motor symptoms.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, taking Indian snakeroot might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Indian snakeroot contains small amounts of the drug yohimbine. In vitro research shows that yohimbine inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of Indian snakeroot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that Indian snakeroot lowers blood glucose levels. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of Indian snakeroot and antihypertensive drugs might increase the risk of hypotension.
Indian snakeroot, which contains reserpine, can reduce both systolic and diastolic blood pressure.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, taking Indian snakeroot might cause additive sedative effects.
Sedation and drowsiness have been reported in clinical trials using Indian snakeroot.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Indian snakeroot might inhibit CYP2D6 enzymes and reduce the metabolism of CYP2D6 substrates.
Indian snakeroot contains small amounts of the drug yohimbine. In vitro research shows that yohimbine inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Ephedrine

Theoretically, taking Indian snakeroot with ephedrine might alter the effects and side effects of ephedrine.
Indian snakeroot contains small amounts of reserpine. Reserpine reduces indirect sympathomimetic drug activity. However, another constituent of Indian snakeroot, yohimbine, has stimulant activity and may increase the risk of adverse effects with ephedrine.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking Indian snakeroot with MAOIs might cause additive effects.
Yohimbine, a constituent of Indian snakeroot, has MAO inhibitory effects. At high doses, yohimbine is a non-selective inhibitor of MAO.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, concomitant use might cause additive effects.
Yohimbine, a constituent of Indian snakeroot, has sympathomimetic effects and increases blood pressure in a dose-dependent manner. Theoretically, taking Indian snakeroot with stimulant drugs can have additive stimulant and hypertensive effects.

Likelihood Possible Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, concomitant use might alter the effects of Indian snakeroot and increase the risk of adverse effects.
A small clinical study in patients taking TCAs for at least 4 weeks shows that receiving doses of intravenous yohimbine, a constituent of Indian snakeroot, 2.5-20 mg daily for up to 7 days precipitates severe anxiety, agitation, and tremor. Also, concomitant use of TCAs with Indian snakeroot may decrease the effects of other rauwolfia alkaloids.

Likelihood Possible Evidence D
Sarpagandha root powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sarpagandha Powder, from the product label.

Vedic Care

See all Vedic Care products
Name
Vedic Care, USA
City
New Brunswick
State
NJ
ZipCode
08901
Phone Number
1-612-888-3342
Web Address
www.thevedicstore.com
Pharmacist Counseling Corner

Sarpagandha Powder by Vedic Care: Common Questions

Does Sarpagandha Powder by Vedic Care interact with any medications?
Yes. Based on its ingredients, Sarpagandha Powder has a known interaction with 843 medications, including 83 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sarpagandha Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — the product should be avoided during pregnancy because its alkaloids may harm your developing baby, and avoided while breastfeeding because reserpine passes into breast milk. If you're planning pregnancy or are currently pregnant or breastfeeding, talk with your doctor before considering any herbal supplement.
What are the most common side effects?
The most common side effects are abdominal pain, slow heartbeat, nasal congestion, diarrhea, low blood pressure, increased appetite, nightmares, drowsiness, and weight gain. Rare but serious effects include irregular heartbeat, seizures, depression, and heart attack.
Does it cause depression?
Yes — Indian snakeroot can trigger depression, especially in people with a history of mood problems. This appears dose-related and may worsen with longer use, though research suggests depression is less likely if you take it for fewer than 40 days.
Is there proof this actually works?
No — the evidence for Indian snakeroot is insufficient for abdominal pain, insomnia, insect bites, and psychosis. We don't have reliable data showing whether it helps these conditions.
Why does this need medical supervision?
Indian snakeroot contains potent alkaloids that can cause serious side effects, including heart problems and depression. It also interacts with many common medications in ways that can be dangerous. These risks mean it should only be used under a doctor's direct oversight, not on your own.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sarpagandha Powder label
Go deeper

The Full Monographs Behind Sarpagandha Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Indian Snakeroot

Interacts with 843 drugs

Indian snakeroot is a traditional Ayurvedic plant that contains reserpine, a compound with real blood-pressure-lowering and sedative effects. Because its potent alkaloids can cause serious s...

Read the full Indian Snakeroot monograph →
Sources

Sources & How We Checked

Sarpagandha Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 43 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indian Snakeroot 43 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  5. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Young DS. Effects of Drugs on Clinical Laboratory Tests 4th ed. Washington: AACC Press, 1995.
  8. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  9. Teloken C, Rhoden EL, Sogari P, et al. Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction. J Urol 1998;159:122-4. PubMed
  10. Jacobsen FM. Fluoxetine-induced sexual dysfunction and an open trial of yohimbine. J Clin Psychiatry 1992;53:119-22.
  11. Hollander E, McCarley A. Yohimbine treatment of sexual side effects induced by serotonin reuptake blockers. J Clin Psychiatry 1992;53:207-9.
  12. Sandler B, Aronson P. Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Urol 1993;41:343-5. PubMed
  13. Kearney T, Tu N, Haller C. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Ann Pharmacother 2010;44:1022-9. PubMed
  14. VandenBrink, B. M., Foti, R. S., Rock, D. A., Wienkers, L. C., and Wahlstrom, J. L. Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition. Drug Metab Dispos. 2012;40(1):47-53. PubMed
  15. Mustonen, P., Savola, J., and Lassila, R. Atipamezole, an imidazoline-type alpha(2)-adrenoceptor inhibitor, binds to human platelets and inhibits their adrenaline-induced aggregation more effectively than yohimbine. Thromb.Res 8-1-2000;99(3):231-237.
  16. Bagheri, H., Schmitt, L., Berlan, M., and Montastruc, J. L. Effect of 3 weeks treatment with yohimbine on salivary secretion in healthy volunteers and in depressed patients treated with tricyclic antidepressants. Br J Clin Pharmacol 1992;34(6):555-558. PubMed
  17. Swann, A. C., Birnbaum, D., Jagar, A. A., Dougherty, D. M., and Moeller, F. G. Acute yohimbine increases laboratory-measured impulsivity in normal subjects. Biol.Psychiatry 5-15-2005;57(10):1209-1211. PubMed
  18. Adeniyi, A. A., Brindley, G. S., Pryor, J. P., and Ralph, D. J. Yohimbine in the treatment of orgasmic dysfunction. Asian J Androl 2007;9(3):403-407. PubMed
  19. Giampreti, A., Lonati, D., Locatelli, C., Rocchi, L., and Campailla, M. T. Acute neurotoxicity after yohimbine ingestion by a body builder. Clin Toxicol.(Phila) 2009;47(8):827-829. PubMed
  20. Myers, A. and Barrueto, F., Jr. Refractory priapism associated with ingestion of yohimbe extract. J Med Toxicol. 2009;5(4):223-225.
  21. Berlin, I., Crespo-Laumonnier, B., Cournot, A., Landault, C., Aubin, F., Legrand, J. C., and Puech, A. J. The alpha 2-adrenergic receptor antagonist yohimbine inhibits epinephrine-induced platelet aggregation in healthy subjects. Clin Pharmacol.Ther. 199
  22. Swann, A. C. Mechanisms of impulsivity in bipolar disorder and related illness. Epidemiol.Psichiatr.Soc. 2010;19(2):120-130.
  23. Landis, E. and Shore, E. Yohimbine-induced bronchospasm. Chest 1989;96(6):1424. PubMed
  24. Susset, J. G., Tessier, C. D., Wincze, J., Bansal, S., Malhotra, C., and Schwacha, M. G. Effect of yohimbine hydrochloride on erectile impotence: a double-blind study. J Urol. 1989;141(6):1360-1363. PubMed
  25. Braddock, L., Cowen, P. J., Elliott, J. M., Fraser, S., and Stump, K. Binding of yohimbine and imipramine to platelets in depressive illness. Psychol.Med 1986;16(4):765-773. PubMed
  26. Charney, D. S., Heninger, G. R., and Sternberg, D. E. Assessment of alpha 2 adrenergic autoreceptor function in humans: effects of oral yohimbine. Life Sci 6-7-1982;30(23):2033-2041.
  27. Boon, N. A., Elliott, J. M., Grahame-Smith, D. G., John-Green, T., and Stump, K. A comparison of alpha 2-adrenoreceptor binding characteristics of intact human platelets identified by [3H]-yohimbine and [3H]- dihydroergocryptine. J Auton.Pharmacol 1983;3
  28. Siddiqui, M. A., More-O'Ferrall, D., Hammod, R. S., Baime, R. V., and Staddon, A. P. Agranulocytosis associated with yohimbine use. Arch.Intern.Med 6-10-1996;156(11):1235-1237.
  29. Mann, K., Klingler, T., Noe, S., Roschke, J., Muller, S., and Benkert, O. Effects of yohimbine on sexual experiences and nocturnal penile tumescence and rigidity in erectile dysfunction. Arch.Sex Behav. 1996;25(1):1-16. PubMed
  30. Riley AJ, Goodman R, Kellett JM, and et al. Double blind trial of yohimbine hydrochloride in the treatment of erection inadequacy. Sexual Marital Ther 1989;4(1):17-26. DOI
  31. Ruck B, Shih RD, Marcus SM. Hypertensive crisis from herbal treatment of impotence. Am J Emerg Med. 1999;17:317-318. PubMed
  32. Wylie KR. Yohimbine and sinusitis. Br J Psychiatry. 1996;169(3):384-5. PubMed
  33. Lobay D. Rauwolfia in the Treatment of Hypertension. Integr Med (Encinitas). 2015 Jun;14(3):40-6.
  34. Lowinger P. Rauwolfia serpentina in the control of anxiety. Psychiatr Q. 1957 Jul;31(3):445-53. PubMed
  35. Sheldon MB, Kotte JH. Effect of Rauwolfia serpentina and reserpine on the blood pressure in essential hypertension; a long-term double-blind study. Circulation. 1957 Aug;16(2):200-6.
  36. Vakil RJ. A clinical trial of Rauwolfia serpentina in essential hypertension. Br Heart J. 1949 Oct;11(4):350-5. PubMed
  37. Azmi MB, Qureshi SA. Methanolic Root Extract of Rauwolfia serpentina Benth Improves the Glycemic, Antiatherogenic, and Cardioprotective Indices in Alloxan-Induced Diabetic Mice. Adv Pharmacol Sci. 2012;2012:376429.
  38. Azmi MB, Qureshi SA. Rauwolfia serpentina improves altered glucose and lipid homeostasis in fructose-induced type 2 diabetic mice. Pak J Pharm Sci. 2016 Sep;29(5):1619-1624.
  39. Achor RW, Hanson NO, Gifford RW Jr. Hypertension treated with Rauwolfia serpentina (whole root) and with reserpine; controlled study disclosing occasional severe depression. J Am Med Assoc. 1955 Oct 29;159(9):841-5. PubMed
  40. Wilkins RW, Judson WE. The use of Rauwolfia serpentina in hypertensive patients. N Engl J Med. 1953 Jan 8;248(2):48-53.
  41. Ryan JJ, Hanes DA, Corroon J, Taylor J, Bradley R. Prospective safety evaluation of a cardiovascular health dietary supplement in adults with prehypertension and stage I hypertension. J Altern Complement Med 2019;25(2):249-56. doi:10.1089/acm.2018.0311. PubMed
  42. Bharucha AE, Skaar T, Andrews CN, et al Relationship of cytochrome P450 pharmacogenetics to the effects of yohimbine on gastrointestinal transit and catecholamines in healthy subjects. Neurogastroenterol Motil. 2008;20(8):891-9. PubMed
  43. Schmauss M, Laakmann G, Dieterle D. Effects of alpha 2-receptor blockade in addition to tricyclic antidepressants in therapy-resistant depression. J Clin Psychopharmacol. 1988;8(2):108-11.

See these in context on the Indian Snakeroot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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