Selenium 200 mcg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Selenium 200 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Selenium 200 mcg is a dietary supplement by Sundown Naturalist with 1 active ingredient. Its ingredients are commonly taken for thyroid health support, antioxidant support, immune support.Based on those ingredients, 321 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Selenium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Selenium 200 mcg by Sundown Naturalist
Ask about any prescription or over-the-counter medication and we check it for interactions with Selenium 200 mcg by Sundown Naturalist — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Selenium 200 mcg by Sundown Naturalist
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: selenium at 200 micrograms per tablet. Selenium is a mineral your body needs in small amounts for thyroid function, immune health, and antioxidant protection.
The inactive ingredients are brewer's yeast, cellulose, croscarmellose, stearic acid, silica, and vegetable magnesium stearate — standard tablet binders and fillers.
Does it work?
Couldn't assess
The evidence supports selenium for treating selenium deficiency — that's a likely effective use. For Kashin-Beck disease (a joint and bone condition linked to low selenium), autoimmune thyroiditis (inflammation of the thyroid), and pre-eclampsia (high blood pressure in pregnancy), the evidence is promising but not conclusive — possibly effective.
For dyslipidemia (abnormal blood lipids), the evidence suggests it's not effective at improving those levels.
How safe is it?
Well-documented data
Selenium at your dose of 200 mcg is generally well tolerated when you stay below the daily upper limit of 400 mcg. The most common side effects at normal doses are mild — gastric discomfort, headache, and rash.
However, excess selenium is toxic. High doses can cause hair loss, skin rashes, fatigue, nail changes, nausea, vomiting, and weight loss; in rare cases, very high amounts have caused multi-organ failure.
Long-term excess exposure may also increase the risk of amyotrophic lateral sclerosis (ALS), a serious nerve disorder. Research also shows selenium supplements increase the risk of squamous cell skin cancer and may not prevent basal cell carcinoma.
For pregnancy, the safety data is mixed — there's some evidence it's possibly unsafe, though dietary amounts appear acceptable. For breastfeeding, the limited data suggests it's possibly safe.
Because of the conflicting pregnancy information, talk with your doctor or pharmacist about whether this dose is right for you if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
Moderate interaction found
Before starting, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (Moderate risk of increased bleeding), barbiturates (Moderate risk of prolonged sedation), warfarin (Moderate risk of interference with its blood-thinning effect), or immunosuppressants (Moderate risk of reduced effectiveness). Minor interactions also exist with oral contraceptives and niacin.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This selenium supplement is suitable for people with a documented selenium deficiency or those at risk for one. If you take blood thinners, immunosuppressants, barbiturates, warfarin, oral contraceptives, or niacin, you should check with your doctor or pharmacist before adding it.
Don't exceed 400 mcg per day, and avoid high-dose supplementation unless your healthcare provider directs it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Selenium 200 mcg, straight from the product label.
| Brand | Sundown Naturalist |
|---|---|
| Barcode (UPC) | 030768001063 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Sep 22, 2016 |
| DSLD ID | 64895 |
| Product type | Mineral |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Selenium 200 mcg by Sundown Naturalist, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Selenium | 200 mcg | 286% |
Other ingredients: Brewer's Yeast, Cellulose, Croscarmellose, Stearic Acid, Silica, Vegetable Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
IMPORTANT FACTS YOU SHOULD KNOW Selenium is an essential trace mineral that is important for wellness.* As an antioxidant, Selenium helps fight against cell-damaging free radicals in the body.* Selenium also supports the immune system.*
Quality Guaranteed Lab Tested Laboratory tested to meet strict quality control standards for potency, purity and disintegration. 100% Quality Guaranteed.
Actual size
Supports Prostate & Immune System Health*
Suggested/Recommended/Usage/Directions
DIRECTIONS: FOR ADULTS, TAKE ONE (1) TABLET DAILY, PREFERABLY WITH A MEAL.
Formulation
No milk or milk derivatives, lactose, sugar, preservatives, soy, artificial color, artificial flavor, sodium.
Vegetarian Formula
Precautions
WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Avoid this product if you are allergic to yeast.
Discontinue use and consult your doctor if any adverse reactions occur.
KEEP OUT OF REACH OF CHILDREN.
TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.
Contains wheat ingredients.
Storage
STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
2016
General
Prod. No. 44639 10F B51846
Seals/Symbols
100% Quality Assurance Laboratory Tested
FDA Statement of Identity
Dietary Supplement
Formula
Contains wheat ingredients.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Selenium 200 mcg by Sundown Naturalist label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Selenium 200 mcg by Sundown Naturalist
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
Selenium
Interacts with321 drugs
Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...
Selenium monograph & interactionsOther (inactive) ingredients: Brewer's Yeast, Cellulose, Croscarmellose, Stearic Acid, Silica, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Selenium 200 mcg by Sundown Naturalist Drug Interactions
HelloPharmacist Interaction Report
Sundown Naturalist Selenium 200 mcg interacts with several medication types through its single active ingredient, selenium.
The most serious documented interaction is with blood thinners (anticoagulants) and antiplatelet drugs — selenium may increase bleeding risk by enhancing the antiplatelet effect, which is a Moderate severity concern.
Read the full breakdown — every affected drug type, severity by severity
Selenium also carries Moderate interactions with immunosuppressants (it may reduce their effectiveness by stimulating your immune system), barbiturates (it may prolong their sedating effects by slowing how your liver breaks them down), and warfarin specifically (it may interfere with warfarin's activity, possibly by displacing it from binding sites or affecting vitamin K-dependent clotting factors). There are also Minor interactions with oral contraceptives (which may raise your selenium levels, though the clinical significance isn't clear) and niacin (selenium might reduce niacin's beneficial effects on HDL cholesterol).
Additionally, selenium has no interactions documented beyond those listed above. Altogether, these interactions span 321 individual medications.
Check your exact medications with the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Selenium 200 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Selenium 200 mcg interact with 321 drugs. Click any drug to see the details.
1 of the 1 ingredient in Selenium 200 mcg interact with drugs. Each result below shows which ingredient is responsible. Selenium
Betamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Betamethasone Dipropionate, Calcipotriene interactionBetamethasone ValerateLuxiq
How Betamethasone Valerate interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Betamethasone Valerate interactionBetrixabanBevyxxa
How Betrixaban interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Betrixaban interactionBimekizumab-bkzxBimzelx
How Bimekizumab-bkzx interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Bimekizumab-bkzx interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Bivalirudin interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Bromfenac Sodium interactionButabarbital SodiumButisol Sodium, Sarisol #2
How Butabarbital Sodium interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butabarbital Sodium interactionButabarbital, Hyoscyamine, PhenazopyridinePyridium Plus
How Butabarbital, Hyoscyamine, Phenazopyridine interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butabarbital, Hyoscyamine, Phenazopyridine interactionButabarbital, Phenobarbital, SecobarbitalS.B.P.
How Butabarbital, Phenobarbital, Secobarbital interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butabarbital, Phenobarbital, Secobarbital interactionButalbital, Phenobarbital, SecobarbitalTribarb
How Butalbital, Phenobarbital, Secobarbital interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butalbital, Phenobarbital, Secobarbital interactionCabliviCablivi
How Cablivi interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Cablivi interactionCamphor, Hyoscyamine, Passif, Phenobarbital, Scopolamine, ValerianNevrotose #3
How Camphor, Hyoscyamine, Passif, Phenobarbital, Scopolamine, Valerian interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Camphor, Hyoscyamine, Passif, Phenobarbital, Scopolamine, Valerian interactionCangrelorKengreal
How Cangrelor interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Cangrelor interactionCiclesonideAlvesco, Omnaris, Zetonna
How Ciclesonide interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Ciclesonide interactionCilostazolPletal
How Cilostazol interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Cilostazol interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cisplatin interactionCladribineLeustatin, Mavenclad
How Cladribine interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cladribine interactionClopidogrelPlavix
How Clopidogrel interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Clopidogrel interactionCopanlisibAliqopa
How Copanlisib interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Copanlisib interactionCortisone AcetateCortisone Tablets, Cortone
How Cortisone Acetate interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cortisone Acetate interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cyclophosphamide interactionCyclosporineCequa, Ciclosporine, Gengraf, Neoral, Sandimmune, Verkazia +1 more
How Cyclosporine interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cyclosporine interactionDaclizumabZenapax, Zinbryta
How Daclizumab interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Daclizumab interactionDalteparinFragmin
How Dalteparin interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Dalteparin interactionDanaparoidOrgaran
How Danaparoid interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Danaparoid interactionDefibrotide SodiumDefitelio
How Defibrotide Sodium interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Defibrotide Sodium interactionDeflazacortEmflaza
How Deflazacort interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Deflazacort interactionDehydrocholic Acid, Homatropine Methylbromide, PhenobarbitalG.B.S.
How Dehydrocholic Acid, Homatropine Methylbromide, Phenobarbital interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Dehydrocholic Acid, Homatropine Methylbromide, Phenobarbital interactionDenosumabProlia, XGEVA
How Denosumab interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Denosumab interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Selenium 200 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Selenium
Anticoagulant/Antiplatelet Drugs
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.
Barbiturates
Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.
Immunosuppressants
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.
Warfarin (Coumadin)
Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.
Contraceptive Drugs
Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.
Niacin
Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.
Brand information
Manufacturer and brand details for Selenium 200 mcg, from the product label.
Sundown Naturalist
See all Sundown Naturalist products- Name
- Rexall Sundown, Inc.
- City
- Boca Raton
- State
- FL
- ZipCode
- 33487
- Phone Number
- 1-888-848-2435
Selenium 200 mcg by Sundown Naturalist: Common Questions
Does Selenium 200 mcg by Sundown Naturalist interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is selenium used for?
Is 200 mcg of selenium safe?
Can selenium cause side effects?
Does selenium interact with my blood thinner?
Can I take this while pregnant?
Will this interfere with my warfarin?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Selenium 200 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Selenium 200 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Selenium 200 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Selenium 36 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Trafikowska U, Zachara BA, Wiacek M, et al. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. Acta Paediatr 1996;85:1143-5. PubMed
- Duffield-Lillico AJ, Slate EH, Reid ME, et al. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. J Natl Cancer Inst 2003;95:1477-81.. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Schiavon R, Freeman GE, Guidi GC, et al. Selenium enhances prostacyclin production by cultured endothelial cells: possible explanation for increased bleeding times in volunteers taking selenium as a dietary supplement. Thromb Res 1984;34:389-96. PubMed
- Davila JC, Edds GT, Osuna O, Simpson CF. Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium. Am J Vet Res 1983;44:1877-83. DOI
- Heese HD, Lawrence MA, Dempster WS, Pocock F. Reference concentrations of serum selenium and manganese in healthy nulliparas. S Afr Med J 1988;73:163-5.
- Lloyd B, Lloyd RS, Clayton BE. Effect of smoking, alcohol and other factors on the selenium status of a healthy population. J Epidemiol Commun Health 1983;37:213-7. PubMed
- Capel ID, Jenner M, Williams DC, et al. The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. J Steroid Biochem 1981;14:729-32. PubMed
- Contempre B, Dumont JE, Ngo B, et al. Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium. J Clin Endocrinol PubMed
- Hofbauer LC, Spitzweg C, Magerstadt RA, Heufelder AE. Selenium-induced thyroid dysfunction. Postgrad Med J 1997;73:103-4. PubMed
- Debski B, Milner JA. Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem 2004;15:548-53. PubMed
- Ishikawa M, Sasaki M, Koiwai K, et al. Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. J Pharmacobiodyn 1992;15:377-85. PubMed
- Lippmann SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the selenium and vitamin E cancer prevention trial (SELECT). JAMA 2009;301:39-51. DOI
- Reid SM, Middleton P, Cossich MC, Crowther CA. Interventions for clinical and subclinical hypothyroidism in pregnancy. Cochrane Database Syst Rev 2010;(7):CD007752. PubMed
- Vinceti, M., Wei, E. T., Malagoli, C., Bergomi, M., and Vivoli, G. Adverse health effects of selenium in humans. Rev.Environ.Health 2001;16(4):233-251. PubMed
- Abrams, C. K., Siram, S. M., Galsim, C., Johnson-Hamilton, H., Munford, F. L., and Mezghebe, H. Selenium deficiency in long-term total parenteral nutrition. Nutr Clin Pract 1992;7(4):175-178. PubMed
- Spiller, H. A. and Pfiefer, E. Two fatal cases of selenium toxicity. Forensic Sci Int 8-24-2007;171(1):67-72. PubMed
- Negro, R., Greco, G., Mangieri, T., Pezzarossa, A., Dazzi, D., and Hassan, H. The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol.Metab 2007;92(4):1263-1268. PubMed
- Alexander, J. Selenium. Novartis.Found.Symp 2007;282:143-149.
- Salonen, J. T., Salonen, R., Seppanen, K., Rinta-Kiikka, S., Kuukka, M., Korpela, H., Alfthan, G., Kantola, M., and Schalch, W. Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial
- Kupka, R., Mugusi, F., Aboud, S., Msamanga, G. I., Finkelstein, J. L., Spiegelman, D., and Fawzi, W. W. Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and chil
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- Peretz, A., Neve, J., Desmedt, J., Duchateau, J., Dramaix, M., and Famaey, J. P. Lymphocyte response is enhanced by supplementation of elderly subjects with selenium-enriched yeast. Am.J Clin.Nutr. 1991;53(5):1323-1328. PubMed
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