Serenaid Ingredients & Drug Interactions
by Klaire Labs
What is this page for?
First and foremost: checking Serenaid against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Serenaid is a dietary supplement by Klaire Labs with 1 active ingredient.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Serenaid by Klaire Labs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Serenaid contains six active enzymes that work in your digestive tract. Protease and lactase are the two with documented safety and effectiveness profiles.
Lactase helps break down lactose, the natural sugar in milk and dairy products. Protease is a digestive enzyme that breaks down proteins.
The product also contains peptidase, dipeptidyl peptidase-IV, endopeptidase, exopeptidase, and a proprietary enzyme blend — all meant to support protein digestion. The capsule itself is vegetarian, and the inactive ingredients are microcrystalline cellulose and ascorbyl palmitate (a form of vitamin C).
Does it work?
Strong evidence
Lactase in this product is effective for lactose intolerance — the condition where you have trouble digesting milk sugar. For colic and prematurity, the evidence isn't established enough to rate it.
We don't hold effectiveness data for protease or the other digestive enzymes in Serenaid, so we can't speak to how well they work.
How safe is it?
Well-documented data
Protease and lactase are generally well tolerated in adults when used as directed. Both can occasionally cause digestive upset or allergic reactions — rarely, some people have reported contact dermatitis or allergic rhinoconjunctivitis (nasal and eye itching) from exposure to powdered forms in occupational settings.
For pregnancy, protease safety has not been established and is best avoided unless prescribed by your doctor. Lactase is likely safe in pregnancy, though checking with your doctor first is wise.
During breastfeeding, there's limited safety data for protease, so medical advice is recommended before use; lactase acts only in the gut and is safer, but still worth discussing with your pharmacist first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we hold no interaction data for peptidase, dipeptidyl peptidase-IV, endopeptidase, exopeptidase, or the proprietary enzyme blends in this product — if you take any prescription medications, ask your pharmacist to review them against these specific ingredients.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Serenaid is a digestive enzyme blend that may help if you struggle with dairy or protein digestion. If you're pregnant or breastfeeding, or take any regular medications, talk to your pharmacist before starting — we couldn't check all the ingredients for drug interactions, and protease safety isn't established in pregnancy.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Serenaid, straight from the product label.
| Brand | Klaire Labs |
|---|---|
| Barcode (UPC) | 790616123186 |
| Net contents | 180 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 19, 2022 |
| DSLD ID | 264721 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Serenaid by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Protease | 0 NP | -- |
| Lactase | 20 mg | -- |
| Peptidase | 0 NP | -- |
| Dipeptidyl Peptidase-IV | 0 NP | -- |
| Endopeptidase | 0 NP | -- |
| Exopeptidase | 0 NP | -- |
| Exorphinase Proprietary Enzyme Blend | 455 mg | -- |
| Peptidase and Protease Enzymes | 0 NP | -- |
Other ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Ascorbyl Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
A Multi-enzyme
Free of the following common allergens: Milk/casein, eggs, fish, shellfish, tree nuts, peanuts, and gluten. Contains no artificial colors, flavors, or preservatives.
Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.
FDA Statement of Identity
Dietary Supplement
Formula
ITH DPP-IV activity
Precautions
Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product.
Keep out of reach of children.
Do not use if shrinkwrap is broken or missing.
Suggested/Recommended/Usage/Directions
Suggested Use: 2 capsules at the beginning of each meal or as directed by a healthcare professional.
General Statements
Units are those used in the Food Chemicals Codex (FCC).
Storage
Store in a cool, dry place (59 degrees F - 85 degrees F) away from direct light.
Brand IP Statement(s)
SFI
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Serenaid by Klaire Labs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Serenaid by Klaire Labs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Exorphinase Proprietary Enzyme Blend
- › Peptidase and Protease Enzymes
Other (inactive) ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.
Serenaid by Klaire Labs Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Serenaid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Serenaid, from the product label.
Klaire Labs
See all Klaire Labs products- Name
- SFI USA
- City
- Reno
- State
- NV
- ZipCode
- 89521
- Web Address
- Klaire.com
Serenaid by Klaire Labs: Common Questions
Does Serenaid by Klaire Labs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will Serenaid help me digest dairy?
Is it safe to take Serenaid while pregnant?
Can I take this while breastfeeding?
What are these enzymes supposed to do?
Could I be allergic to this product?
Are there any fillers in Serenaid?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Serenaid is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
Serenaid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC